Vitamin B12 deficiency causes: Difference between revisions

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*Insufficient diet
*Insufficient diet
*[[Malabsorption syndrome]]
*[[Malabsorption syndrome]]
*[[Gastrectomy]]
*[[Gastrectomy]] <ref name="pmid28457771">{{cite journal |vauthors=Camarero-Shelly M, Pellitero S, Martínez E, Puig R, Leis A, Zavala R, Granada ML, Pastor C, Moreno P, Tarascó J, Balibrea J, Puig-Domingo M |title=[Vitamin B12 levels in the patient population attending an urban health centre in Madrid] |language=Spanish; Castilian |journal=Semergen |volume=44 |issue=3 |pages=161–167 |date=April 2018 |pmid=28457771 |doi=10.1016/j.semerg.2017.03.006 |url=}}</ref>
*[[Gastritis]]
*[[Gastritis]]
*[[Ileal resection]]
*[[Ileal resection]]
Line 22: Line 22:


===Causes by Organ System===
===Causes by Organ System===
{|style="width:80%; height:100px" border="1"
{| style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular'''
| style="width:25%" bgcolor="LightSteelBlue" ; border="1" |'''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes
| style="width:75%" bgcolor="Beige" ; border="1" | No underlying causes
|-
|-
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning'''
| bgcolor="LightSteelBlue" | '''Chemical/Poisoning'''
|bgcolor="Beige"| [[Nitroux oxide abuse]]
| bgcolor="Beige" | [[Nitroux oxide abuse]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Dental'''
| '''Dental'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Dermatologic'''
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| '''Drug Side Effect'''
|bgcolor="Beige"| [[Cimetidine]],  [[Glyburide ]],  [[Metformin hydrochloride]],  [[Neomycin]],  [[Omeprazole]],  [[Pantoprazole]],  [[Prolonged antiacid use]],  [[Rabeprazole]],  [[Ranitidine hydrochloride]],  [[Saxagliptin hydrochloride ]]
| bgcolor="Beige" | [[Cimetidine]],  [[Glyburide ]] ,  [[Metformin hydrochloride]],  [[Neomycin]],  [[Omeprazole]],  [[Pantoprazole]],  [[Prolonged antiacid use]],  [[Rabeprazole]],  [[Ranitidine hydrochloride]],  [[Saxagliptin hydrochloride ]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Ear Nose Throat'''
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Endocrine'''
| '''Endocrine'''
|bgcolor="Beige"| [[Graves' disease]]
| bgcolor="Beige" | [[Graves' disease]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Environmental'''
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| '''Gastroenterologic'''
|bgcolor="Beige"| [[Achlorhydria]],  [[Atrophic gastritis]],  [[Bariatric surgery]],  [[Blind loop syndrome]],  [[Bothriocephalosis]],  [[Celiac disease]],  [[Chronic pancreatitis]],  [[Cobalamin malabsorption]],  [[Crohn's disease]],  [[Gastrectomy]],  [[Gastritis]],  [[Grasbeck-imerslund disease]],  [[Ileal resection]],  [[Imerslund-najman-grasbeck anemia]],  [[Malabsorption syndrome]],  [[Pancreatic insufficiency]],  [[Pancreatitis]],  [[Postgastrectomy syndrome]],  [[Small bowel disease]]
| bgcolor="Beige" | [[Achlorhydria]],  [[Atrophic gastritis]],  [[Bariatric surgery]],  [[Blind loop syndrome]],  [[Bothriocephalosis]],  [[Celiac disease]],  [[Chronic pancreatitis]],  [[Cobalamin malabsorption]],  [[Crohn's disease]],  [[Gastrectomy]],  [[Gastritis]],  [[Grasbeck-imerslund disease]],  [[Ileal resection]],  [[Imerslund-najman-grasbeck anemia]],  [[Malabsorption syndrome]],  [[Pancreatic insufficiency]],  [[Pancreatitis]],  [[Postgastrectomy syndrome]],  [[Small bowel disease]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Genetic'''
| '''Genetic'''
|bgcolor="Beige"| [[Homocystinuria]],  [[Mthfr deficiency]]
| bgcolor="Beige" | [[Homocystinuria]],  [[Mthfr deficiency]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Hematologic'''
| '''Hematologic'''
|bgcolor="Beige"| [[Grasbeck-imerslund disease]],  [[Imerslund-najman-grasbeck anemia]],  [[Intrinsic factor deficiency ]],  [[Juvenile megaloblastic anemia]],  [[Macrocytic anemia]],  [[Megaloblastic anemia]],  [[Pernicious anemia]],  [[Transcobalamin deficiency]]
| bgcolor="Beige" | [[Grasbeck-imerslund disease]],  [[Imerslund-najman-grasbeck anemia]],  [[Intrinsic factor deficiency ]] ,  [[Juvenile megaloblastic anemia]],  [[Macrocytic anemia]],  [[Megaloblastic anemia]],  [[Pernicious anemia]],  [[Transcobalamin deficiency]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Iatrogenic'''
| '''Iatrogenic'''
|bgcolor="Beige"| [[Bariatric surgery]],  [[Gastrectomy]],  [[Ileal resection]],  [[N2o anesthesia ]],  [[Postgastrectomy syndrome]]
| bgcolor="Beige" | [[Bariatric surgery]],  [[Gastrectomy]],  [[Ileal resection]],  [[N2o anesthesia ]] ,  [[Postgastrectomy syndrome]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Infectious Disease'''
| '''Infectious Disease'''
|bgcolor="Beige"| [[Bothriocephalosis]],  [[Diphyllobothrium latum]]
| bgcolor="Beige" | [[Bothriocephalosis]],  [[Diphyllobothrium latum]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Neurologic'''
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| [[Cobalamin malabsorption]],  [[Excessive alcohol consumption]],  [[Insufficient diet]],  [[Veganism]],  [[Vegetarianism]]
| bgcolor="Beige" | [[Cobalamin malabsorption]],  [[Excessive alcohol consumption]],  [[Insufficient diet]],  [[Veganism]],  [[Vegetarianism]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Oncologic'''
| '''Oncologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Ophthalmologic'''
| '''Ophthalmologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Overdose/Toxicity'''
| '''Overdose/Toxicity'''
|bgcolor="Beige"| [[Excessive alcohol consumption]],  [[Nitroux oxide abuse]]
| bgcolor="Beige" | [[Excessive alcohol consumption]],  [[Nitroux oxide abuse]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Psychiatric'''
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Pulmonary'''
| '''Pulmonary'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
| '''Renal/Electrolyte'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Rheumatology/Immunology/Allergy'''
| '''Rheumatology/Immunology/Allergy'''
|bgcolor="Beige"| [[Crohn's disease]],  [[Systemic lupus erythematosus]]
| bgcolor="Beige" | [[Crohn's disease]],  [[Systemic lupus erythematosus]]
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Sexual'''
| '''Sexual'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Trauma'''
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Urologic'''
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
| bgcolor="Beige" | No underlying causes
|-
|-
|-bgcolor="LightSteelBlue"
|- bgcolor="LightSteelBlue"
| '''Miscellaneous'''
| '''Miscellaneous'''
|bgcolor="Beige"| [[Idiopathic]]
| bgcolor="Beige" | [[Idiopathic]]
|-
|-
|}
|}

Revision as of 18:09, 6 June 2018

Vitamin B12 deficiency Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Common causes of vitamin B12 deficiency include insufficient dietary intake, as well as diseases and iatrogenic procedures causing problems in absorption. It is common in individuals adhering to vegetarian or vegan diets without external supplementation, due to primary sources including animal products such as meat, eggs, and dairy.

Causes

Common Causes

Causes by Organ System

Cardiovascular No underlying causes
Chemical/Poisoning Nitroux oxide abuse
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect Cimetidine, Glyburide , Metformin hydrochloride, Neomycin, Omeprazole, Pantoprazole, Prolonged antiacid use, Rabeprazole, Ranitidine hydrochloride, Saxagliptin hydrochloride
Ear Nose Throat No underlying causes
Endocrine Graves' disease
Environmental No underlying causes
Gastroenterologic Achlorhydria, Atrophic gastritis, Bariatric surgery, Blind loop syndrome, Bothriocephalosis, Celiac disease, Chronic pancreatitis, Cobalamin malabsorption, Crohn's disease, Gastrectomy, Gastritis, Grasbeck-imerslund disease, Ileal resection, Imerslund-najman-grasbeck anemia, Malabsorption syndrome, Pancreatic insufficiency, Pancreatitis, Postgastrectomy syndrome, Small bowel disease
Genetic Homocystinuria, Mthfr deficiency
Hematologic Grasbeck-imerslund disease, Imerslund-najman-grasbeck anemia, Intrinsic factor deficiency , Juvenile megaloblastic anemia, Macrocytic anemia, Megaloblastic anemia, Pernicious anemia, Transcobalamin deficiency
Iatrogenic Bariatric surgery, Gastrectomy, Ileal resection, N2o anesthesia , Postgastrectomy syndrome
Infectious Disease Bothriocephalosis, Diphyllobothrium latum
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic Cobalamin malabsorption, Excessive alcohol consumption, Insufficient diet, Veganism, Vegetarianism
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity Excessive alcohol consumption, Nitroux oxide abuse
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy Crohn's disease, Systemic lupus erythematosus
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous Idiopathic

Cause in Alphabetical Order

The unnamed parameter 2= is no longer supported. Please see the documentation for {{columns-list}}.
3

References

  1. ↑ Camarero-Shelly M, Pellitero S, Martínez E, Puig R, Leis A, Zavala R, Granada ML, Pastor C, Moreno P, Tarascó J, Balibrea J, Puig-Domingo M (April 2018). "[Vitamin B12 levels in the patient population attending an urban health centre in Madrid]". Semergen (in Spanish; Castilian). 44 (3): 161–167. doi:10.1016/j.semerg.2017.03.006. PMID 28457771.

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