Focal segmental glomerulosclerosis history and symptoms: Difference between revisions
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The hallmark of focal segmental glomerulosclerosis is nephrotic-range proteinuria.<ref name="pmid7702047">{{cite journal| author=Rydel JJ, Korbet SM, Borok RZ, Schwartz MM| title=Focal segmental glomerular sclerosis in adults: presentation, course, and response to treatment. | journal=Am J Kidney Dis | year= 1995 | volume= 25 | issue= 4 | pages= 534-42 | pmid=7702047 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7702047}} </ref> | The hallmark of focal segmental glomerulosclerosis is nephrotic-range proteinuria.<ref name="pmid7702047">{{cite journal| author=Rydel JJ, Korbet SM, Borok RZ, Schwartz MM| title=Focal segmental glomerular sclerosis in adults: presentation, course, and response to treatment. | journal=Am J Kidney Dis | year= 1995 | volume= 25 | issue= 4 | pages= 534-42 | pmid=7702047 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7702047}} </ref> | ||
===History=== | ===History=== | ||
Patients with focal segmental glomerulosclerosis may have a positive history of: | Patients with focal segmental glomerulosclerosis may have a positive history of:<ref name="pmid22187987">{{cite journal |vauthors=D'Agati VD, Kaskel FJ, Falk RJ |title=Focal segmental glomerulosclerosis |journal=N. Engl. J. Med. |volume=365 |issue=25 |pages=2398–411 |date=December 2011 |pmid=22187987 |doi=10.1056/NEJMra1106556 |url=}}</ref> | ||
*Positive family history of FSGN | *Positive family history of FSGN | ||
*Heroin abuse | *Heroin abuse | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
History and Symptoms
The hallmark of focal segmental glomerulosclerosis is nephrotic-range proteinuria.[1]
History
Patients with focal segmental glomerulosclerosis may have a positive history of:[2]
- Positive family history of FSGN
- Heroin abuse
- Chronic viral infections such as hepatitis B
- Medications such as bisphosphonates
Common Symptoms
Common symptoms of focal segmental glomerulosclerosis include:[3][4]
- Proteinuria
- Hematuria
- Anasarca
- Headache and blurry vision which is suggestive of high blood pressure
Less Common Symptoms
Less common symptoms of [disease name] include
- Fatigue
- Malaise
- Symptoms of chronic renal failure such as anuria, edema
References
- ↑ Rydel JJ, Korbet SM, Borok RZ, Schwartz MM (1995). "Focal segmental glomerular sclerosis in adults: presentation, course, and response to treatment". Am J Kidney Dis. 25 (4): 534–42. PMID 7702047.
- ↑ D'Agati VD, Kaskel FJ, Falk RJ (December 2011). "Focal segmental glomerulosclerosis". N. Engl. J. Med. 365 (25): 2398–411. doi:10.1056/NEJMra1106556. PMID 22187987.
- ↑ Choy BY, Chan TM, Lai KN (November 2006). "Recurrent glomerulonephritis after kidney transplantation". Am. J. Transplant. 6 (11): 2535–42. doi:10.1111/j.1600-6143.2006.01502.x. PMID 16939521.
- ↑ Baum MA, Ho M, Stablein D, Alexander SR (December 2002). "Outcome of renal transplantation in adolescents with focal segmental glomerulosclerosis". Pediatr Transplant. 6 (6): 488–92. PMID 12453201.