Minimal change disease diagnostic study of choice: Difference between revisions
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== Overview == | == Overview == | ||
The diagnostic study of choice for minimal change disease is renal biopsy. | |||
== Diagnostic Study of choice == | == Diagnostic Study of choice == | ||
* | * The diagnostic study of choice for minimal change disease is renal biopsy.<ref name="pmid27940460">{{cite journal |vauthors=Vivarelli M, Massella L, Ruggiero B, Emma F |title=Minimal Change Disease |journal=Clin J Am Soc Nephrol |volume=12 |issue=2 |pages=332–345 |date=February 2017 |pmid=27940460 |pmc=5293332 |doi=10.2215/CJN.05000516 |url=}}</ref> | ||
* With four weeks of treatment with steroid therapy, most of the patients with minimal change disease (MCD) will respond positively. | * With four weeks of treatment with steroid therapy, most of the patients with minimal change disease (MCD) will respond positively. | ||
* Before considering renal biopsy steroid therapy can be initiated in patients who fulfill the following criteria because of the invasive process of the biopsy. | * Before considering renal biopsy steroid therapy can be initiated in patients who fulfill the following criteria because of the invasive process of the biopsy. | ||
Revision as of 14:54, 13 June 2018
Overview
The diagnostic study of choice for minimal change disease is renal biopsy.
Diagnostic Study of choice
- The diagnostic study of choice for minimal change disease is renal biopsy.[1]
- With four weeks of treatment with steroid therapy, most of the patients with minimal change disease (MCD) will respond positively.
- Before considering renal biopsy steroid therapy can be initiated in patients who fulfill the following criteria because of the invasive process of the biopsy.
- Patients must be older than 1 year and less than 12 years.
- Normal complement levels No signs of hypertension, gross hematuria, or a marked increase in serum creatinine.
- By following this protocol in patients with minimal change disease we can avoid unnecessary invasive approach in almost 80% of the patients.
- ↑ Vivarelli M, Massella L, Ruggiero B, Emma F (February 2017). "Minimal Change Disease". Clin J Am Soc Nephrol. 12 (2): 332–345. doi:10.2215/CJN.05000516. PMC 5293332. PMID 27940460.