Methemoglobinemia other diagnostic studies: Difference between revisions
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It consist of placing couple of drops of blood on white filter paper, and check for change in the color of the blood when you expose the paper to oxygen. Simply deoxygenated hemoglobin will change its color from dark red to bright red, whereas methemoglobin will not. <ref name="pmid19818531">{{cite journal| author=Shihana F, Dissanayake DM, Buckley NA, Dawson AH| title=A simple quantitative bedside test to determine methemoglobin. | journal=Ann Emerg Med | year= 2010 | volume= 55 | issue= 2 | pages= 184-9 | pmid=19818531 | doi=10.1016/j.annemergmed.2009.07.022 | pmc=2977536 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19818531 }} </ref> | It consist of placing couple of drops of blood on white filter paper, and check for change in the color of the blood when you expose the paper to oxygen. Simply deoxygenated hemoglobin will change its color from dark red to bright red, whereas methemoglobin will not. <ref name="pmid19818531">{{cite journal| author=Shihana F, Dissanayake DM, Buckley NA, Dawson AH| title=A simple quantitative bedside test to determine methemoglobin. | journal=Ann Emerg Med | year= 2010 | volume= 55 | issue= 2 | pages= 184-9 | pmid=19818531 | doi=10.1016/j.annemergmed.2009.07.022 | pmc=2977536 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19818531 }} </ref> | ||
==References== | ==References== | ||
Revision as of 13:14, 15 June 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Template:Aksiniya K. Stevasarova, M.D.
Overview
Congenital (Hereditary) Methemoglobinemia
There are three main congenital conditions that lead to methemoglobinemia:
1. Cytochrome b5 reductase deficiency and pyruvate kinase deficiency
2. G6PD deficiency
3. Presence of abnormal hemoglobin.
Acquired or Acute Methemoglobinemia
Most common cause include different oxidant drugs, toxins or chemicals
Other diagnostic studies
One additional bedside methods exists for detection of methemoglobin in the blood.
It consist of placing couple of drops of blood on white filter paper, and check for change in the color of the blood when you expose the paper to oxygen. Simply deoxygenated hemoglobin will change its color from dark red to bright red, whereas methemoglobin will not. [1]
References
- ↑ Shihana F, Dissanayake DM, Buckley NA, Dawson AH (2010). "A simple quantitative bedside test to determine methemoglobin". Ann Emerg Med. 55 (2): 184–9. doi:10.1016/j.annemergmed.2009.07.022. PMC 2977536. PMID 19818531.