Myasthenia gravis laboratory findings: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{CMG}} | {{CMG}} | ||
{{Myasthenia gravis}} | {{Myasthenia gravis}} | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
Laboratory findings consistent with the diagnosis of myasthenia gravis include: | |||
=== | ==== Acetylcholine receptor antibodies: ==== | ||
One of the most important steps in confirming the diagnosis of myasthenia gravis is detecting AchR-Ab. About 85 percent of patients with generalized myasthenia gravis are seropositive for this Abs.(8-9) these antybodies are specific for myasthenia gravis but in rare cases we have false positive such as lambert-eaton, motor neuron disease, polymyositis(10-15-16) and even in the disease not related to myasthenia such as primary biliary cholangitis and systemic lupus erythematosus.(17-18) since the patient can become seronegative after immune modulating therapy, this test should be done before treatment. (12) | |||
=== | ==== MuSK antibodies: ==== | ||
==References== | ==References== |
Revision as of 14:35, 19 June 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Myasthenia gravis Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Myasthenia gravis laboratory findings On the Web |
American Roentgen Ray Society Images of Myasthenia gravis laboratory findings |
Risk calculators and risk factors for Myasthenia gravis laboratory findings |
Laboratory Findings
Laboratory findings consistent with the diagnosis of myasthenia gravis include:
Acetylcholine receptor antibodies:
One of the most important steps in confirming the diagnosis of myasthenia gravis is detecting AchR-Ab. About 85 percent of patients with generalized myasthenia gravis are seropositive for this Abs.(8-9) these antybodies are specific for myasthenia gravis but in rare cases we have false positive such as lambert-eaton, motor neuron disease, polymyositis(10-15-16) and even in the disease not related to myasthenia such as primary biliary cholangitis and systemic lupus erythematosus.(17-18) since the patient can become seronegative after immune modulating therapy, this test should be done before treatment. (12)