Cavernous sinus thrombosis laboratory findings: Difference between revisions
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Laboratory findings consistent with the diagnosis of cavernous sinus thrombosis include: | Laboratory findings consistent with the diagnosis of cavernous sinus thrombosis include: | ||
* | *Neutrophilic-predominant leukocytosis<ref name="pmid26722163">{{cite journal| author=Syed A, Bell B, Hise J, Philip J, Spak C, Opatowsky MJ| title=Bilateral cavernous sinus and superior ophthalmic vein thrombosis in the setting of facial cellulitis. | journal=Proc (Bayl Univ Med Cent) | year= 2016 | volume= 29 | issue= 1 | pages= 36-8 | pmid=26722163 | doi= | pmc=4677848 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26722163 }} </ref> | ||
*Lumbar puncture may be used to detect possible meningitis | *Lumbar puncture may be used to detect possible meningitis<ref name="pmid15455548">{{cite journal| author=Chang CS, Liou CW, Huang CC, Lui CC, Chang KC| title=Cavernous sinus thrombosis and cerebral infarction caused by Fusobacterium nucleatum infection. | journal=Chang Gung Med J | year= 2004 | volume= 27 | issue= 6 | pages= 459-63 | pmid=15455548 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15455548 }} </ref> | ||
*Blood culture | *Blood culture may be positive<ref name="pmid27781123">{{cite journal| author=Arian M, Kamali A, Tabatabaeichehr M, Arashnia P| title=Septic Cavernous Sinus Thrombosis: A Case Report. | journal=Iran Red Crescent Med J | year= 2016 | volume= 18 | issue= 8 | pages= e34961 | pmid=27781123 | doi=10.5812/ircmj.34961 | pmc=5068248 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27781123 }} </ref><ref name="pmid26041393">{{cite journal| author=Nishida A, Ogata T, Kudo M, Fukuhara K, Fukae J, Tsuboi Y| title=[A case with both infectious cavernous sinus thrombosis and Lemierre syndrome due to intraoral resident flora]. | journal=Rinsho Shinkeigaku | year= 2015 | volume= 55 | issue= 7 | pages= 483-9 | pmid=26041393 | doi=10.5692/clinicalneurol.cn-000676 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26041393 }} </ref><ref name="pmid17380002">{{cite journal| author=Hoshino C, Satoh N, Sugawara S, Kuriyama C, Kikuchi A, Ohta M| title=Septic cavernous sinus thrombosis complicated by narrowing of the internal carotid artery, subarachnoid abscess and multiple pulmonary septic emboli. | journal=Intern Med | year= 2007 | volume= 46 | issue= 6 | pages= 317-23 | pmid=17380002 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17380002 }} </ref> | ||
* | *Metabolic acidosis<ref name="pmid26722163">{{cite journal| author=Syed A, Bell B, Hise J, Philip J, Spak C, Opatowsky MJ| title=Bilateral cavernous sinus and superior ophthalmic vein thrombosis in the setting of facial cellulitis. | journal=Proc (Bayl Univ Med Cent) | year= 2016 | volume= 29 | issue= 1 | pages= 36-8 | pmid=26722163 | doi= | pmc=4677848 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26722163 }} </ref> | ||
*Hypernatremia<ref name="pmid26722163">{{cite journal| author=Syed A, Bell B, Hise J, Philip J, Spak C, Opatowsky MJ| title=Bilateral cavernous sinus and superior ophthalmic vein thrombosis in the setting of facial cellulitis. | journal=Proc (Bayl Univ Med Cent) | year= 2016 | volume= 29 | issue= 1 | pages= 36-8 | pmid=26722163 | doi= | pmc=4677848 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26722163 }} </ref> | |||
*Elevated ESR and CRP<ref name="pmid27781123">{{cite journal| author=Arian M, Kamali A, Tabatabaeichehr M, Arashnia P| title=Septic Cavernous Sinus Thrombosis: A Case Report. | journal=Iran Red Crescent Med J | year= 2016 | volume= 18 | issue= 8 | pages= e34961 | pmid=27781123 | doi=10.5812/ircmj.34961 | pmc=5068248 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27781123 }} </ref><ref name="pmid24605316">{{cite journal| author=Pant B, Joshi HC, Isser DK| title=Atypical Presentation of Cavernous Sinus Infection with Intracavernous ICA Aneurysm. | journal=Indian J Otolaryngol Head Neck Surg | year= 2014 | volume= 66 | issue= 1 | pages= 118-21 | pmid=24605316 | doi=10.1007/s12070-012-0560-3 | pmc=3938714 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24605316 }} </ref> | |||
==References== | ==References== | ||
Revision as of 16:13, 5 July 2018
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Differentiating Cavernous sinus thrombosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Laboratory Findings
Laboratory findings consistent with the diagnosis of cavernous sinus thrombosis include:
- Neutrophilic-predominant leukocytosis[1]
- Lumbar puncture may be used to detect possible meningitis[2]
- Blood culture may be positive[3][4][5]
- Metabolic acidosis[1]
- Hypernatremia[1]
- Elevated ESR and CRP[3][6]
References
- ↑ 1.0 1.1 1.2 Syed A, Bell B, Hise J, Philip J, Spak C, Opatowsky MJ (2016). "Bilateral cavernous sinus and superior ophthalmic vein thrombosis in the setting of facial cellulitis". Proc (Bayl Univ Med Cent). 29 (1): 36–8. PMC 4677848. PMID 26722163.
- ↑ Chang CS, Liou CW, Huang CC, Lui CC, Chang KC (2004). "Cavernous sinus thrombosis and cerebral infarction caused by Fusobacterium nucleatum infection". Chang Gung Med J. 27 (6): 459–63. PMID 15455548.
- ↑ 3.0 3.1 Arian M, Kamali A, Tabatabaeichehr M, Arashnia P (2016). "Septic Cavernous Sinus Thrombosis: A Case Report". Iran Red Crescent Med J. 18 (8): e34961. doi:10.5812/ircmj.34961. PMC 5068248. PMID 27781123.
- ↑ Nishida A, Ogata T, Kudo M, Fukuhara K, Fukae J, Tsuboi Y (2015). "[A case with both infectious cavernous sinus thrombosis and Lemierre syndrome due to intraoral resident flora]". Rinsho Shinkeigaku. 55 (7): 483–9. doi:10.5692/clinicalneurol.cn-000676. PMID 26041393.
- ↑ Hoshino C, Satoh N, Sugawara S, Kuriyama C, Kikuchi A, Ohta M (2007). "Septic cavernous sinus thrombosis complicated by narrowing of the internal carotid artery, subarachnoid abscess and multiple pulmonary septic emboli". Intern Med. 46 (6): 317–23. PMID 17380002.
- ↑ Pant B, Joshi HC, Isser DK (2014). "Atypical Presentation of Cavernous Sinus Infection with Intracavernous ICA Aneurysm". Indian J Otolaryngol Head Neck Surg. 66 (1): 118–21. doi:10.1007/s12070-012-0560-3. PMC 3938714. PMID 24605316.