Sideroblastic anemia differential diagnosis: Difference between revisions

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Revision as of 14:53, 2 August 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nazia Fuad M.D.

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Overview

Differential Diagnosis

Sideroblastic anemia must be differentiated from other causes of microcytic hypochromic anemia: iron deficiency anemia, thalassemia, anemia of chronic disease, lead poisoning, and blood loss.

• Tissue iron overload from sideroblastic anemia may act similar to hereditary hemochromatosis with liver cirrhosis, diabetes, congestive heart failure, and cardiac arrhythmias.

ALA Dehydratase Deficiency Porphyria
Acute Myeloid Leukemia (AML)
Congenital Erythropoietic Porphyria
Hereditary Coproporphyria
Iron Deficiency Anemia
Myelodysplastic Syndrome
Secondary Thrombocytosis

On the basis [symptom 1], [symptom 2], and [symptom 3], [disease name] must be differentiated from [disease 1], [disease 2], [disease 3], [disease 4], [disease 5], and [disease 6].

		Symptoms			Physical examination			Lab Findings			Imaging			Histopathology
Diseases		Clinical manifestations						Para-clinical findings							Gold standard	Additional findings
		Symptoms			Physical examination			Para-clinical findings
		Symptom 1	Symptom 2	Symptom 3	Physical exam 1	Physical exam 2	Physical exam 3	Lab 1	Lab 2	Lab 3	Imaging 1	Imaging 2	Imaging 3	Histopathology
Microcytic hypochromic anemia	Iron deficiency anemia
	Thalasemia
	Anemia of chronic disease
	Lead poisoning
	Blood loss
Diseases		Symptom 1	Symptom 2	Symptom 3	Physical exam 1	Physical exam 2	Physical exam 3	Lab 1	Lab 2	Lab 3	Imaging 1	Imaging 2	Imaging 3	Histopathology	Gold standard	Additional findings
Tissue iron overload

References

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@@ Line 23: / Line 23: @@
 {|
 |- style="background: #4479BA; color: #FFFFFF; text-align: center;"
-! rowspan="4"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Diseases
+! colspan="2" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
-| colspan="6" rowspan="1"  style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Clinical manifestations'''
+| colspan="6" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Clinical manifestations'''
-! colspan="7" rowspan="2"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Para-clinical findings
+! colspan="7" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para-clinical findings
-| colspan="1" rowspan="4"  style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Gold standard'''
+| colspan="1" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Gold standard'''
-! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;|Additional findings
+! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Additional findings
 |-
-| colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Symptoms'''
+| colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Symptoms'''
-! colspan="3" rowspan="2"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical examination
+! colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical examination
 |-
-! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab Findings
+! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings
-! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging
+! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
-! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|Histopathology
+! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology
 |-
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 1
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptom 1
-! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 2
+! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptom 2
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 3
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptom 3
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 1
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam 1
-! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 2
+! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam 2
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 3
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam 3
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 1
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 1
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 2
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 2
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 3
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 3
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 1
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 1
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 2
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 2
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 3
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 3
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 1
+| rowspan="5" style="background: #DCDCDC; padding: 5px; text-align: center;" |Microcytic hypochromic
+anemia
+|Iron deficiency anemia
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 66: / Line 68: @@
 | style="background: #F5F5F5; padding: 5px;" |
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 2
+|Thalasemia
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 83: / Line 85: @@
 | style="background: #F5F5F5; padding: 5px;" |
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 3
+|Anemia of chronic disease
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 99: / Line 101: @@
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
+|-
+|Lead poisoning
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|-
+|Blood loss
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|
+|
 |- style="background: #4479BA; color: #FFFFFF; text-align: center;"
-!Diseases
+! colspan="2" |Diseases
 !Symptom 1
 ! colspan="1" rowspan="1" |Symptom 2
@@ Line 117: / Line 153: @@
 !Additional findings
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 4
+| rowspan="3" style="background: #DCDCDC; padding: 5px; text-align: center;" |Tissue iron overload
+|
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 134: / Line 171: @@
 | style="background: #F5F5F5; padding: 5px;" |
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 5
+|
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |
@@ Line 151: / Line 188: @@
 | style="background: #F5F5F5; padding: 5px;" |
 |-
-| style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 6
+|
 | style="background: #F5F5F5; padding: 5px;" |
 | style="background: #F5F5F5; padding: 5px;" |

Sideroblastic anemia differential diagnosis: Difference between revisions

Revision as of 14:53, 2 August 2018

Overview

Differential Diagnosis

References

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