Sideroblastic anemia epidemiology and demographics: Difference between revisions
Nazia Fuad (talk | contribs) |
Nazia Fuad (talk | contribs) No edit summary |
||
| Line 3: | Line 3: | ||
=== Incidence === | === Incidence === | ||
* | * [[Incidence]] of sideroblastic anemia is approximately [number range] per 100,000 individuals worldwide. | ||
* In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide. | * In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide. | ||
=== Prevalence === | === Prevalence === | ||
* The prevalence of sideroblastic anemia is approximately 800 per 100,000 individuals worldwide. | * The [[prevalence]] of sideroblastic anemia is approximately 800 per 100,000 individuals worldwide. | ||
* In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide. | * In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide. | ||
* The prevalence of [disease/malignancy] is estimated to be [number] cases annually. | * The prevalence of [disease/malignancy] is estimated to be [number] cases annually. | ||
=== Case-fatality rate/Mortality rate === | === Case-fatality rate/Mortality rate === | ||
* In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a | * In [year], the [[incidence]] of [disease name] is approximately [number range] per 100,000 individuals with a [[mortality rate]] of [number range]%. | ||
* The case-fatality rate/mortality rate of [disease name] is approximately [number range]. | * The case-fatality rate/mortality rate of [disease name] is approximately [number range]. | ||
=== Age === | === Age === | ||
* Patients of all age groups may develop sideroblastic anemia. | * Patients of all age groups may develop sideroblastic anemia. | ||
* Congenital X-linked sideroblastic anemia due to ''ALAS'' mutation can remain undiagnosed and then present late in the fourth to eighth decades of life. | * [[Congenital]] X-linked sideroblastic anemia due to ''ALAS'' mutation can remain undiagnosed and then present late in the fourth to eighth decades of life. | ||
* The incidence of acquired sideroblastic anemia increases with age; the median age at diagnosis is 74 years. | * The incidence of acquired sideroblastic anemia increases with age; the median age at diagnosis is 74 years. | ||
* Chronic sideroblastic anemia is usually first diagnosed among middle and older age group.<ref name="pmid18772852">{{cite journal |vauthors=Hadnagy C |title=Primary acquired sideroblastic anemia and myelodysplastic syndrome from a geriatric point of view |journal=Z Gerontol |volume=24 |issue=2 |pages=105–9 |date=1991 |pmid=1877285 |doi= |url=}}</ref> | * Chronic sideroblastic anemia is usually first diagnosed among middle and older age group.<ref name="pmid18772852">{{cite journal |vauthors=Hadnagy C |title=Primary acquired sideroblastic anemia and [[myelodysplastic syndrome]] from a geriatric point of view |journal=Z Gerontol |volume=24 |issue=2 |pages=105–9 |date=1991 |pmid=1877285 |doi= |url=}}</ref> | ||
=== Race === | === Race === | ||
Revision as of 16:52, 7 August 2018
|
Sideroblastic anemia Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Sideroblastic anemia epidemiology and demographics On the Web |
|
American Roentgen Ray Society Images of Sideroblastic anemia epidemiology and demographics |
|
Sideroblastic anemia epidemiology and demographics in the news |
|
Risk calculators and risk factors for Sideroblastic anemia epidemiology and demographics |
Incidence
- Incidence of sideroblastic anemia is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
Prevalence
- The prevalence of sideroblastic anemia is approximately 800 per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
- The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
Case-fatality rate/Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
- Patients of all age groups may develop sideroblastic anemia.
- Congenital X-linked sideroblastic anemia due to ALAS mutation can remain undiagnosed and then present late in the fourth to eighth decades of life.
- The incidence of acquired sideroblastic anemia increases with age; the median age at diagnosis is 74 years.
- Chronic sideroblastic anemia is usually first diagnosed among middle and older age group.[1]
Race
- There is no racial predilection to sideroblastic anemia.
Gender
- Males are more commonly affected than females in X-linked recessive types of sideroblastic anemia.
- A female would have to inherit 1 abnormal chromosome from each parent to acquire the sideroblastic anemia.
- Primary acquired sideroblastic anemia was found in 60.4% male and 39.6% female.[1]
Region
- The majority of [disease name] cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
Developing Countries
Epidemiology and Demographics
Hereditary sideroblastic anemia, being sex-linked, primarily affects males.
• Primary acquired sideroblastic anemia is usually a disease of the elderly.In 25 bone marrow biopsies of children younger than 13 years from Atlanta, Georgia (United States), with anemia, the prevalence of ringed sideroblasts was 8%. [50]
In France, the prevalence of ringed sideroblasts was 57% in patients with primary MDS. [51] In the United Kingdom, amongst healthy volunteers undergoing bone marrow biopsy, siderotic granules (not ring sideroblasts) were present in 29% of men and 19% of women. [52]
Although usually manifested in childhood, congenital X-linked sideroblastic anemia due to ALAS mutation can remain undiagnosed and then present late in the fourth to eighth decades of life. [53, 54] The median age of occurrence of primary acquired sideroblastic anemia is 74 years. [55]
X-linked recessive types of sideroblastic anemia occur more commonly in males. A female would have to inherit 1 abnormal chromosome from each parent to acquire the disease. Progesterone and pregnancy have been reported to induce relapse of sideroblastic anemia. [
References
- ↑ 1.0 1.1 Hadnagy C (1991). "Primary acquired sideroblastic anemia and myelodysplastic syndrome from a geriatric point of view". Z Gerontol. 24 (2): 105–9. PMID 1877285.