Sideroblastic anemia physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nazia Fuad M.D.

Physical Examination

Appearance of the Patient

• Patients with sideroblastic anemia usually appear pale
• Growth retardation in children

Vital Signs

• Hypothermia

Skin

• Photosensitivity (porphyria)
• Petechiae (myelodysplastic syndrome)

HEENT

• HEENT examination of patients with sideroblastic anemia is usually normal except
• Oral - Lead line on teeth margins
• Eyes - Optic atrophy (associated with DIDMOAD syndrome)

Neck

• Jugular venous distension.

Lungs

• Pulmonary examination of patients with sideroblastic anemia is usually normal except
• Shortness of breath
• Rales

Heart

• Arrythmias
• Heart failure
• Chest pain
• S3 gallop

Abdomen

• Splenomegaly

• Diarrhea
• Hepatomegaly

Back

• Back examination of patients with sideroblastic anemia is usually normal.

Genitourinary

• Genitourinary examination of patients with sideroblastic anemia is usually normal except
• Pink staining of diapers in childrens from porphyrins in urine

Neuromuscular

• Ataxia,
• Hyporeflexia
• Incoordination

Extremities

• Extremities examination of patients with sideroblastic anemia is usually normal.