Hydrocephalus pathophysiology: Difference between revisions

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Hydrocephalus mostly results due to CSF flow [[obstruction]], hindering the free passage of cerebrospinal fluid through the ventricular system and it can also be caused by overproduction of cerebrospinal fluid (relative obstruction).
Hydrocephalus mostly results due to CSF flow [[obstruction]], hindering the free passage of cerebrospinal fluid through the ventricular system and it can also be caused by overproduction of cerebrospinal fluid (relative obstruction).
==Pathophysiology==
==Pathophysiology==
* In a normal healthy person, [[CSF]] continuously circulates through the brain and its ventricles and the [[spinal cord]] and is continuously drained away into the circulatory system.  
* The pathophysiology of hydrocephalus is given below:.<ref>[http://www.ninds.nih.gov/disorders/hydrocephalus/detail_hydrocephalus.htm "Hydrocephalus Fact Sheet"], National Institute of Neurological Disorders and Stroke. (August 2005).</ref> 
* Hydrocephalus is usually due to blockage of [[cerebral spinal fluid]] ([[CSF]]) outflow in the brain ventricles or in the [[subarachnoid space]] over the brain.
**In a normal healthy person, [[CSF]] continuously circulates through the brain and its ventricles and the [[spinal cord]].
* If the foramina (''pl.'') of the [[fourth ventricle]] or the [[cerebral aqueduct]] are blocked, cereobrospinal fluid (CSF) can accumulate within the ventricles. This condition is called '''internal hydrocephalus'''
**[[CSF]] is continuously drained into the circulatory system.  
* Alternatively, the condition may result from an overproduction of the CSF fluid, from a congenital malformation blocking normal drainage of the fluid, or from complications of [[head injuries]] or infections.<ref>[http://www.ninds.nih.gov/disorders/hydrocephalus/detail_hydrocephalus.htm "Hydrocephalus Fact Sheet"], National Institute of Neurological Disorders and Stroke. (August 2005).</ref> 
**Hydrocephalus is usually due to blockage of [[cerebral spinal fluid]] ([[CSF]]) outflow in the brain ventricles or in the [[subarachnoid space]] over the brain.
* In a hydrocephalic situation, the fluid accumulates in the ventricles, and the [[skull]] may become enlarged because of the great volume of fluid pressing against the brain and skull.  
**If the foramina of the [[fourth ventricle]] or the [[cerebral aqueduct]] are blocked, [[cereobrospinal fluid]] ([[CSF]]) can accumulate within the [[ventricles]]. This condition is called [[Internal hydrocephalus]].
* Infants and young children with hydrocephalus typically have abnormally large heads, because the pressure of the fluid causes the individual skull bones which have not knitted with each other yet to bulge outward at their juncture points.
**The another condition that causes increase in [[CSF]] is from an overproduction of the CSF fluid.
* The [[elevated intracranial pressure]] may cause compression of the brain, leading to brain damage and other complications. Conditions among affected individual vary widely.  Children who have had hydrocephalus may have very small ventricles.
**It is due to the congenital malformation of the tract that causes blockage of the normal [[CSF]] drainage.
* Compression of the nervous tissue usually results in [[irreversible brain damage]].
**Another condition causes increase in [[CSF]] is due the complications of [[head injuries]] and [[infections]]
**In patient with hydrocephalus, the [[CSF]] accumulates in the ventricles, which compresses the skull and brain which results in increase [[skull size]].
**The [[elevated intracranial pressure]] may cause compression of the brain, leading to brain damage and other complications.
**Children who have had hydrocephalus may have very small ventricles.
**Compression of the nervous tissue usually results in [[irreversible brain damage]].


== References ==
== References ==
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Revision as of 18:43, 13 August 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor-In-Chief: Cafer Zorkun M.D., PhD.,Kalsang Dolma, M.B.B.S.[2]

Overview

Hydrocephalus mostly results due to CSF flow obstruction, hindering the free passage of cerebrospinal fluid through the ventricular system and it can also be caused by overproduction of cerebrospinal fluid (relative obstruction).

Pathophysiology

  • The pathophysiology of hydrocephalus is given below:.[1]

References

  1. "Hydrocephalus Fact Sheet", National Institute of Neurological Disorders and Stroke. (August 2005).


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