Sideroblastic anemia physical examination: Difference between revisions
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== Physical Examination == | == Physical Examination == | ||
Patients with sideroblastic anemia may exibit following signs.<ref name="pmid26637696">{{cite journal |vauthors=Cazzola M, Malcovati L |title=Diagnosis and treatment of sideroblastic anemias: from defective heme synthesis to abnormal RNA splicing |journal=Hematology Am Soc Hematol Educ Program |volume=2015 |issue= |pages=19–25 |date=2015 |pmid=26637696 |doi=10.1182/asheducation-2015.1.19 |url=}}</ref> | |||
=== Appearance of the Patient === | === Appearance of the Patient === | ||
Revision as of 20:24, 13 August 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nazia Fuad M.D.
Overview
Patients usually presents with signs of anemia with pale skin, dyspnea, tachycardia. Growth retardation is seen in children. Other signs include hypothermia, lead line on teeth margins, photosensitivity, petechiae, optic atrophy, ataxia, incoordination. Hepatosplenomegaly is common patients with iron overload.
Physical Examination
Patients with sideroblastic anemia may exibit following signs.[1]
Appearance of the Patient
- Patients with sideroblastic anemia usually appear pale
- Growth retardation in children
Vital Signs
Skin
HEENT
- HEENT examination of patients with sideroblastic anemia is usually normal except
- Oral - Lead line on teeth margins
- Eyes - Optic atrophy (associated with DIDMOAD syndrome)
Neck
Lungs
Heart
- Arrythmias
- Heart failure
- Chest pain
- S3 gallop
Abdomen
Back
- Back examination of patients with sideroblastic anemia is usually normal.
Genitourinary
- Genitourinary examination of patients with sideroblastic anemia is usually normal except
- Pink staining of diapers in childrens from porphyrins in urine
Neuromuscular
Extremities
- Extremities examination of patients with sideroblastic anemia is usually normal.
References
- ↑ Cazzola M, Malcovati L (2015). "Diagnosis and treatment of sideroblastic anemias: from defective heme synthesis to abnormal RNA splicing". Hematology Am Soc Hematol Educ Program. 2015: 19–25. doi:10.1182/asheducation-2015.1.19. PMID 26637696.