Sideroblastic anemia epidemiology and demographics: Difference between revisions
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=== Age === | === Age === | ||
* Patients of all age groups may develop sideroblastic anemia. | * Patients of all age groups may develop sideroblastic anemia. | ||
* [[Congenital]] X-linked sideroblastic anemia due to ''ALAS'' mutation can remain undiagnosed and then present late in the fourth to eighth decades of life. | * [[Congenital]] X-linked sideroblastic anemia due to ''ALAS'' [[mutation]] can remain undiagnosed and then present late in the fourth to eighth decades of life. | ||
* The incidence of acquired sideroblastic anemia increases with age; the median age at diagnosis is 74 years. | * The incidence of acquired sideroblastic [[anemia]] increases with age; the median age at diagnosis is 74 years. | ||
* Chronic sideroblastic anemia is usually first diagnosed among middle and older age group.<ref name="pmid18772852">{{cite journal |vauthors=Hadnagy C |title=Primary acquired sideroblastic anemia and [[myelodysplastic syndrome]] from a geriatric point of view |journal=Z Gerontol |volume=24 |issue=2 |pages=105–9 |date=1991 |pmid=1877285 |doi= |url=}}</ref> | * Chronic sideroblastic anemia is usually first diagnosed among middle and older age group.<ref name="pmid18772852">{{cite journal |vauthors=Hadnagy C |title=Primary acquired sideroblastic anemia and [[myelodysplastic syndrome]] from a geriatric point of view |journal=Z Gerontol |volume=24 |issue=2 |pages=105–9 |date=1991 |pmid=1877285 |doi= |url=}}</ref> | ||
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=== Gender === | === Gender === | ||
* Males are more commonly affected than females in X-linked recessive types of sideroblastic anemia. | * Males are more commonly affected than females in X-linked recessive types of sideroblastic anemia. | ||
* A female would have to inherit 1 abnormal chromosome from each parent to acquire the sideroblastic anemia. | * A female would have to inherit 1 abnormal [[chromosome]] from each parent to acquire the sideroblastic anemia. | ||
* Primary acquired sideroblastic anemia was found in 60.4% male and 39.6% female.<ref name="pmid18772852" /> | * Primary acquired sideroblastic anemia was found in 60.4% male and 39.6% female.<ref name="pmid18772852" /> | ||
Latest revision as of 14:42, 14 August 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nazia Fuad M.D.
Overview
Patients of all age groups may develop sideroblastic anemia. The incidence of acquired sideroblastic anemia increases with age; the median age at diagnosis is 74 years. Chronic sideroblastic anemia is usually first diagnosed among middle and older age group. There is no racial predilection to sideroblastic anemia. Males are more commonly affected than females in X-linked recessive types of sideroblastic anemia.
Epidemiology and Demographics
Age
- Patients of all age groups may develop sideroblastic anemia.
- Congenital X-linked sideroblastic anemia due to ALAS mutation can remain undiagnosed and then present late in the fourth to eighth decades of life.
- The incidence of acquired sideroblastic anemia increases with age; the median age at diagnosis is 74 years.
- Chronic sideroblastic anemia is usually first diagnosed among middle and older age group.[1]
Race
- There is no racial predilection to sideroblastic anemia.
Gender
- Males are more commonly affected than females in X-linked recessive types of sideroblastic anemia.
- A female would have to inherit 1 abnormal chromosome from each parent to acquire the sideroblastic anemia.
- Primary acquired sideroblastic anemia was found in 60.4% male and 39.6% female.[1]
Region
- Sideroblastic anemia is more prevalent in European countries,in peadiatric population.
References
- ↑ 1.0 1.1 Hadnagy C (1991). "Primary acquired sideroblastic anemia and myelodysplastic syndrome from a geriatric point of view". Z Gerontol. 24 (2): 105–9. PMID 1877285.