Hydrocephalus medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Ahsan Hussain, M.D.[2]

Medical Therapy

• Hydrocephalus is a medical emergency and requires prompt treatment.
• The mainstay of treatment for hydrocephalus is Furosemide.

• Resuscitation:
  • Oxygen.
  • B.P management.
  • End organ perfusion.

• Preferred regimen (1): Hypertonic saline in bolus 250 mL/kg IV.

• Preferred regimen (2): Furosemide 0.5 to 1.0 mg/kg IV q6-12h.

• Preferred regimen (3): Mannitol 0.5-1g/kg in 20% solution IV q6-12h.

• Alternative regimen (1): Glucocorticoids.

• Alternative regimen (2): Pentobarbital 5-20 mg/kg as a bolus followed by 1-4 mg/kg/hr.

• Alternative regimen (3): Acetaminophen 500 mg PO q6h for 7-14 days.