Myasthenia gravis electrocardiogram: Difference between revisions

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==Electrocardiogram==
==Electrocardiogram==
There is controversy about ECG changes in MG.<ref name="pmid1099888">{{cite journal |vauthors=Gibson TC |title=The heart in myasthenia gravis |journal=Am. Heart J. |volume=90 |issue=3 |pages=389–96 |date=September 1975 |pmid=1099888 |doi= |url=}}</ref> these changes are mostly non specific but the fact that they will regress after treatment of MG will rise this suspicion that MG causes these abnormalities.<ref name="pmid14280896">{{cite journal |vauthors=KOHN PM, TUCKER HJ, KOZOKOFF NJ |title=THE CARDIAC MANIFESTATIONS OF MYASTHENIA GRAVIS WITH PARTICULAR REFERENCE TO ELECTROCARDIOGRAPHIC ABNORMALITIES |journal=Am. J. Med. Sci. |volume=249 |issue= |pages=561–70 |date=May 1965 |pmid=14280896 |doi= |url=}}</ref><ref name="pmid139069">{{cite journal |vauthors=Büyüköztürk K, Ozdemir C, Kohen D |title=Electrocardiographic findings in 24 patients with myasthenia gravis |journal=Acta Cardiol |volume=31 |issue=4 |pages=301–5 |date=1976 |pmid=139069 |doi= |url=}}</ref> These abnormalities include  arrhythmias (which can increase the risk of sudden cardiac death<ref name="pmid6507031">{{cite journal |vauthors=Hofstad H, Ohm OJ, Mørk SJ, Aarli JA |title=Heart disease in myasthenia gravis |journal=Acta Neurol. Scand. |volume=70 |issue=3 |pages=176–84 |date=September 1984 |pmid=6507031 |doi= |url=}}</ref>, Q-T prolongation<ref name="pmid139069">{{cite journal |vauthors=Büyüköztürk K, Ozdemir C, Kohen D |title=Electrocardiographic findings in 24 patients with myasthenia gravis |journal=Acta Cardiol |volume=31 |issue=4 |pages=301–5 |date=1976 |pmid=139069 |doi= |url=}}</ref>, conduction disturbances and ST-T changes.<ref name="pmid14280896">{{cite journal |vauthors=KOHN PM, TUCKER HJ, KOZOKOFF NJ |title=THE CARDIAC MANIFESTATIONS OF MYASTHENIA GRAVIS WITH PARTICULAR REFERENCE TO ELECTROCARDIOGRAPHIC ABNORMALITIES |journal=Am. J. Med. Sci. |volume=249 |issue= |pages=561–70 |date=May 1965 |pmid=14280896 |doi= |url=}}</ref><ref name="pmid139069">{{cite journal |vauthors=Büyüköztürk K, Ozdemir C, Kohen D |title=Electrocardiographic findings in 24 patients with myasthenia gravis |journal=Acta Cardiol |volume=31 |issue=4 |pages=301–5 |date=1976 |pmid=139069 |doi= |url=}}</ref><ref name="pmid5371909">{{cite journal |vauthors=Luomanmäki K, Hokkanen E, Heikkilä J |title=Electrocardiogram in myasthenia gravis. Analysis of a series of 97 patients |journal=Ann. Clin. Res. |volume=1 |issue=4 |pages=236–45 |adate=December 1969 |pmid=5371909 |doi= |url=}}</ref>
* There is controversy about ECG changes in MG.<ref name="pmid1099888">{{cite journal |vauthors=Gibson TC |title=The heart in myasthenia gravis |journal=Am. Heart J. |volume=90 |issue=3 |pages=389–96 |date=September 1975 |pmid=1099888 |doi= |url=}}</ref> These changes are mostly non specific but the fact that they will regress after treatment of MG will rise this suspicion that MG causes these abnormalities.<ref name="pmid14280896">{{cite journal |vauthors=KOHN PM, TUCKER HJ, KOZOKOFF NJ |title=THE CARDIAC MANIFESTATIONS OF MYASTHENIA GRAVIS WITH PARTICULAR REFERENCE TO ELECTROCARDIOGRAPHIC ABNORMALITIES |journal=Am. J. Med. Sci. |volume=249 |issue= |pages=561–70 |date=May 1965 |pmid=14280896 |doi= |url=}}</ref><ref name="pmid139069">{{cite journal |vauthors=Büyüköztürk K, Ozdemir C, Kohen D |title=Electrocardiographic findings in 24 patients with myasthenia gravis |journal=Acta Cardiol |volume=31 |issue=4 |pages=301–5 |date=1976 |pmid=139069 |doi= |url=}}</ref>  
* These abnormalities include  arrhythmias (which can increase the risk of sudden cardiac death<ref name="pmid6507031">{{cite journal |vauthors=Hofstad H, Ohm OJ, Mørk SJ, Aarli JA |title=Heart disease in myasthenia gravis |journal=Acta Neurol. Scand. |volume=70 |issue=3 |pages=176–84 |date=September 1984 |pmid=6507031 |doi= |url=}}</ref>, Q-T prolongation<ref name="pmid139069">{{cite journal |vauthors=Büyüköztürk K, Ozdemir C, Kohen D |title=Electrocardiographic findings in 24 patients with myasthenia gravis |journal=Acta Cardiol |volume=31 |issue=4 |pages=301–5 |date=1976 |pmid=139069 |doi= |url=}}</ref>, conduction disturbances and ST-T changes.<ref name="pmid14280896">{{cite journal |vauthors=KOHN PM, TUCKER HJ, KOZOKOFF NJ |title=THE CARDIAC MANIFESTATIONS OF MYASTHENIA GRAVIS WITH PARTICULAR REFERENCE TO ELECTROCARDIOGRAPHIC ABNORMALITIES |journal=Am. J. Med. Sci. |volume=249 |issue= |pages=561–70 |date=May 1965 |pmid=14280896 |doi= |url=}}</ref><ref name="pmid139069">{{cite journal |vauthors=Büyüköztürk K, Ozdemir C, Kohen D |title=Electrocardiographic findings in 24 patients with myasthenia gravis |journal=Acta Cardiol |volume=31 |issue=4 |pages=301–5 |date=1976 |pmid=139069 |doi= |url=}}</ref><ref name="pmid5371909">{{cite journal |vauthors=Luomanmäki K, Hokkanen E, Heikkilä J |title=Electrocardiogram in myasthenia gravis. Analysis of a series of 97 patients |journal=Ann. Clin. Res. |volume=1 |issue=4 |pages=236–45 |adate=December 1969 |pmid=5371909 |doi= |url=}}</ref>


==References==
==References==

Revision as of 16:15, 28 November 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Electrocardiogram

  • There is controversy about ECG changes in MG.[1] These changes are mostly non specific but the fact that they will regress after treatment of MG will rise this suspicion that MG causes these abnormalities.[2][3]
  • These abnormalities include  arrhythmias (which can increase the risk of sudden cardiac death[4], Q-T prolongation[3], conduction disturbances and ST-T changes.[2][3][5]

References

  1. ↑ Gibson TC (September 1975). "The heart in myasthenia gravis". Am. Heart J. 90 (3): 389–96. PMID 1099888.
  2. ↑ 2.0 2.1 KOHN PM, TUCKER HJ, KOZOKOFF NJ (May 1965). "THE CARDIAC MANIFESTATIONS OF MYASTHENIA GRAVIS WITH PARTICULAR REFERENCE TO ELECTROCARDIOGRAPHIC ABNORMALITIES". Am. J. Med. Sci. 249: 561–70. PMID 14280896.
  3. ↑ 3.0 3.1 3.2 Büyüköztürk K, Ozdemir C, Kohen D (1976). "Electrocardiographic findings in 24 patients with myasthenia gravis". Acta Cardiol. 31 (4): 301–5. PMID 139069.
  4. ↑ Hofstad H, Ohm OJ, Mørk SJ, Aarli JA (September 1984). "Heart disease in myasthenia gravis". Acta Neurol. Scand. 70 (3): 176–84. PMID 6507031.
  5. ↑ Luomanmäki K, Hokkanen E, Heikkilä J. "Electrocardiogram in myasthenia gravis. Analysis of a series of 97 patients". Ann. Clin. Res. 1 (4): 236–45. PMID 5371909. Unknown parameter |adate= ignored (help)


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