Myasthenia gravis MRI: Difference between revisions
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== | == MRI == | ||
[[Magnetic resonance imaging]] (MRI) is also a more sensitive way to identify thymomas, and are generally done for this reason. | * MRI may be helpful in the diagnosis of myasthenia gravis. | ||
* [[Magnetic resonance imaging]] (MRI) is also a more sensitive way to identify thymomas, and are generally done for this reason. Findings on MRI suggestive of MG are mostly thymic masses. So many studies suggested a relationship between myasthenia gravis and thymus. This disease mostly occurs in patients with thymic hyperplasia and thymoma and the removal of thymus can reduce the clinical symptom of the patients. Based on this fact, detection of these thymic masses is very important in management of myasthenia gravis.<ref name="pmid7423369">{{cite journal |vauthors=Wechsler AS, Olanow CW |title=Myasthenia gravis |journal=Surg. Clin. North Am. |volume=60 |issue=4 |pages=931–45 |date=August 1980 |pmid=7423369 |doi= |url=}}</ref><ref name="pmid89275">{{cite journal |vauthors=Elias SB, Appel SH |title=Current concepts of pathogenesis and treatment of myasthenia gravis |journal=Med. Clin. North Am. |volume=63 |issue=4 |pages=745–57 |date=July 1979 |pmid=89275 |doi= |url=}}</ref><ref name="pmid7457692">{{cite journal |vauthors=Mintz S, Petersen SR, MacFarland D, Petajan J, Richards RC |title=The current role of thymectomy for myasthenia gravis |journal=Am. J. Surg. |volume=140 |issue=6 |pages=734–7 |date=December 1980 |pmid=7457692 |doi= |url=}}</ref><ref name="pmid4421048">{{cite journal |vauthors=Cohn HE, Solit RW, Schatz NJ, Schlezinger N |title=Surgical treatment in myasthenia gravis. A 27 year experience |journal=J. Thorac. Cardiovasc. Surg. |volume=68 |issue=6 |pages=876–85 |date=December 1974 |pmid=4421048 |doi= |url=}}</ref><ref name="pmid647191">{{cite journal |vauthors=Fraser K, Simpson JA, Crawford J |title=The place of surgery in the treatment of myasthenia gravis |journal=Br J Surg |volume=65 |issue=5 |pages=301–4 |date=May 1978 |pmid=647191 |doi= |url=}}</ref> | |||
* It is suggested that MRI is more accurate than CT scan in differentiating thymic masses.<ref name="pmid26774127">{{cite journal |vauthors=Priola AM, Priola SM, Gned D, Giraudo MT, Fornari A, Veltri A |title=Comparison of CT and chemical-shift MRI for differentiating thymoma from non-thymomatous conditions in myasthenia gravis: value of qualitative and quantitative assessment |journal=Clin Radiol |volume=71 |issue=3 |pages=e157–69 |date=March 2016 |pmid=26774127 |doi=10.1016/j.crad.2015.12.009 |url=}}</ref> | |||
* In a case report done by Vasiliki Zouvelou and colleagues, based on MRI findings it was suggested that MG patients with anti-MuSK antibodies are more prone to have facial and bulbar muscle atrophy.<ref name="pmid22341149">{{cite journal |vauthors=Zouvelou V, Rentzos M, Toulas P, Evdokimidis I |title=AchR-positive myasthenia gravis with MRI evidence of early muscle atrophy |journal=J Clin Neurosci |volume=19 |issue=6 |pages=918–9 |date=June 2012 |pmid=22341149 |doi=10.1016/j.jocn.2011.09.022 |url=}}</ref> | |||
In a case report done by Vasiliki Zouvelou and colleagues, based on MRI findings it was suggested that MG patients with anti-MuSK antibodies are more prone to have facial and bulbar muscle atrophy.<ref name="pmid22341149">{{cite journal |vauthors=Zouvelou V, Rentzos M, Toulas P, Evdokimidis I |title=AchR-positive myasthenia gravis with MRI evidence of early muscle atrophy |journal=J Clin Neurosci |volume=19 |issue=6 |pages=918–9 |date=June 2012 |pmid=22341149 |doi=10.1016/j.jocn.2011.09.022 |url=}}</ref> | |||
==References== | ==References== | ||
Revision as of 16:20, 28 November 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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MRI
- MRI may be helpful in the diagnosis of myasthenia gravis.
- Magnetic resonance imaging (MRI) is also a more sensitive way to identify thymomas, and are generally done for this reason. Findings on MRI suggestive of MG are mostly thymic masses. So many studies suggested a relationship between myasthenia gravis and thymus. This disease mostly occurs in patients with thymic hyperplasia and thymoma and the removal of thymus can reduce the clinical symptom of the patients. Based on this fact, detection of these thymic masses is very important in management of myasthenia gravis.[1][2][3][4][5]
- It is suggested that MRI is more accurate than CT scan in differentiating thymic masses.[6]
- In a case report done by Vasiliki Zouvelou and colleagues, based on MRI findings it was suggested that MG patients with anti-MuSK antibodies are more prone to have facial and bulbar muscle atrophy.[7]
References
- ↑ Wechsler AS, Olanow CW (August 1980). "Myasthenia gravis". Surg. Clin. North Am. 60 (4): 931–45. PMID 7423369.
- ↑ Elias SB, Appel SH (July 1979). "Current concepts of pathogenesis and treatment of myasthenia gravis". Med. Clin. North Am. 63 (4): 745–57. PMID 89275.
- ↑ Mintz S, Petersen SR, MacFarland D, Petajan J, Richards RC (December 1980). "The current role of thymectomy for myasthenia gravis". Am. J. Surg. 140 (6): 734–7. PMID 7457692.
- ↑ Cohn HE, Solit RW, Schatz NJ, Schlezinger N (December 1974). "Surgical treatment in myasthenia gravis. A 27 year experience". J. Thorac. Cardiovasc. Surg. 68 (6): 876–85. PMID 4421048.
- ↑ Fraser K, Simpson JA, Crawford J (May 1978). "The place of surgery in the treatment of myasthenia gravis". Br J Surg. 65 (5): 301–4. PMID 647191.
- ↑ Priola AM, Priola SM, Gned D, Giraudo MT, Fornari A, Veltri A (March 2016). "Comparison of CT and chemical-shift MRI for differentiating thymoma from non-thymomatous conditions in myasthenia gravis: value of qualitative and quantitative assessment". Clin Radiol. 71 (3): e157–69. doi:10.1016/j.crad.2015.12.009. PMID 26774127.
- ↑ Zouvelou V, Rentzos M, Toulas P, Evdokimidis I (June 2012). "AchR-positive myasthenia gravis with MRI evidence of early muscle atrophy". J Clin Neurosci. 19 (6): 918–9. doi:10.1016/j.jocn.2011.09.022. PMID 22341149.