Guillain-Barré syndrome epidemiology and demographics: Difference between revisions
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'''Guillain-Barré syndrome''' ('''GBS''') is an acute, autoimmune, [[neuropathy|polyradiculoneuropathy]] affecting the [[peripheral nervous system]], usually triggered by an acute infectious process. The incidence is approximately 1.2 - 3 / 100,000 persons per year across the world. It is commoner in males compared to female and has two peaks (15-35 years and 50-75 years). Incidence is similar across different races. | '''Guillain-Barré syndrome''' ('''GBS''') is an acute, autoimmune, [[neuropathy|polyradiculoneuropathy]] affecting the [[peripheral nervous system]], usually triggered by an acute infectious process. The incidence is approximately 1.2 - 3 / 100,000 persons per year across the world. It is commoner in males compared to female and has two peaks (15-35 years and 50-75 years). Incidence is similar across different races. | ||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
=== | ===Incidence=== | ||
* It is the commonest cause of acute, flaccid paralysis in USA. | * It is the commonest cause of acute, flaccid paralysis in USA. | ||
* Incidence- 1.2 - 3 / 100,000 persons <ref name="pmid1741839">{{cite journal |author=Day N |title=AIDS and insurer discretion |journal=[[Ohio Medicine : Journal of the Ohio State Medical Association]] |volume=87 |issue=5 |pages=226 |year=1991 |month=May |pmid=1741839 |doi= |url= |accessdate=2012-02-17}}</ref><ref name="pmid1187127">{{cite journal |author=Romhányi I |title=[Letter: The concept of "caucasian race"] |language=Hungarian |journal=[[Orvosi Hetilap]] |volume=116 |issue=41 |pages=2449 |year=1975 |month=October |pmid=1187127 |doi= |url= |accessdate=2012-02-17}}</ref> | * Incidence- 1.2 - 3 / 100,000 persons <ref name="pmid1741839">{{cite journal |author=Day N |title=AIDS and insurer discretion |journal=[[Ohio Medicine : Journal of the Ohio State Medical Association]] |volume=87 |issue=5 |pages=226 |year=1991 |month=May |pmid=1741839 |doi= |url= |accessdate=2012-02-17}}</ref><ref name="pmid1187127">{{cite journal |author=Romhányi I |title=[Letter: The concept of "caucasian race"] |language=Hungarian |journal=[[Orvosi Hetilap]] |volume=116 |issue=41 |pages=2449 |year=1975 |month=October |pmid=1187127 |doi= |url= |accessdate=2012-02-17}}</ref> | ||
* It has been reported all over the world. | * It has been reported all over the world. | ||
* The incidence is around 1.5 - 3 / 100,000 persons | * The incidence is around 1.5 - 3 / 100,000 persons | ||
* The antecedence of [[Campylobacter jejuni]] is commoner in Japan and other Asian countries. Whereas, in American continents and European nations an antecedence of [[cytomegalovirus]] is common. | * The antecedence of [[Campylobacter jejuni]] is commoner in Japan and other Asian countries. Whereas, in American continents and European nations an antecedence of [[cytomegalovirus]] is common. | ||
=== Case mortality rate === | |||
===Age=== | ===Age=== | ||
Revision as of 20:00, 13 December 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Priyamvada Singh, MBBS [2]
Overview
Guillain-Barré syndrome (GBS) is an acute, autoimmune, polyradiculoneuropathy affecting the peripheral nervous system, usually triggered by an acute infectious process. The incidence is approximately 1.2 - 3 / 100,000 persons per year across the world. It is commoner in males compared to female and has two peaks (15-35 years and 50-75 years). Incidence is similar across different races.
Epidemiology and Demographics
Incidence
- It is the commonest cause of acute, flaccid paralysis in USA.
- Incidence- 1.2 - 3 / 100,000 persons [1][2]
- It has been reported all over the world.
- The incidence is around 1.5 - 3 / 100,000 persons
- The antecedence of Campylobacter jejuni is commoner in Japan and other Asian countries. Whereas, in American continents and European nations an antecedence of cytomegalovirus is common.
Case mortality rate
Age
- Incidence increases with age.
- Bimodal distribution - First peak during 15 - 35 yrs and second during old age [3].
- New-borns and infants have the least risks of development of GBS
Races
- Incidence is similar across different races.
Gender
- It occurs more commonly in males compared to females. Male to female ratio 1.5:1
- The incidence has been found to increase post-partum and decreases during pregnancy [4]
References
- ↑ Day N (1991). "AIDS and insurer discretion". Ohio Medicine : Journal of the Ohio State Medical Association. 87 (5): 226. PMID 1741839. Unknown parameter
|month=ignored (help);|access-date=requires|url=(help) - ↑ Romhányi I (1975). "[Letter: The concept of "caucasian race"]". Orvosi Hetilap (in Hungarian). 116 (41): 2449. PMID 1187127. Unknown parameter
|month=ignored (help);|access-date=requires|url=(help) - ↑ Prevots DR, Sutter RW (1997). "Assessment of Guillain-Barré syndrome mortality and morbidity in the United States: implications for acute flaccid paralysis surveillance". The Journal of Infectious Diseases. 175 Suppl 1: S151–5. PMID 9203708. Retrieved 2012-02-17. Unknown parameter
|month=ignored (help) - ↑ Jiang GX, de Pedro-Cuesta J, Strigård K, Olsson T, Link H (1996). "Pregnancy and Guillain-Barré syndrome: a nationwide register cohort study". Neuroepidemiology. 15 (4): 192–200. PMID 8817501.
|access-date=requires|url=(help)