Guillain-Barré syndrome diagnostic study of choice: Difference between revisions
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=== Diagnostic Criteria === | === Diagnostic Criteria === | ||
* There is no single diagnostic study of choice for Guillain Barre syndrome, though GBS may be diagnosed based on NINDS criteria established by National Institute of Neurological Disorders and Stroke:<ref name="pmid2194422">{{cite journal |vauthors=Asbury AK, Cornblath DR |title=Assessment of current diagnostic criteria for Guillain-Barré syndrome |journal=Ann. Neurol. |volume=27 Suppl |issue= |pages=S21–4 |date=1990 |pmid=2194422 |doi= |url=}}</ref> | * There is no single diagnostic study of choice for Guillain Barre syndrome, though GBS may be diagnosed based on NINDS criteria established by National Institute of Neurological Disorders and Stroke:<ref name="pmid2194422">{{cite journal |vauthors=Asbury AK, Cornblath DR |title=Assessment of current diagnostic criteria for Guillain-Barré syndrome |journal=Ann. Neurol. |volume=27 Suppl |issue= |pages=S21–4 |date=1990 |pmid=2194422 |doi= |url=}}</ref><ref name="pmid677829">{{cite journal |vauthors= |title=Criteria for diagnosis of Guillain-Barré syndrome |journal=Ann. Neurol. |volume=3 |issue=6 |pages=565–6 |date=June 1978 |pmid=677829 |doi=10.1002/ana.410030628 |url=}}</ref> | ||
** Progressive ascending weakness or paralysis usually starting from legs, involving are 4 limbs, the trunk, bulbar and facial muscles, and external ocular muscles. | ** Progressive ascending weakness or paralysis usually starting from legs, involving are 4 limbs, the trunk, bulbar and facial muscles, and external ocular muscles. | ||
** Areflexia or decreased reflexes in affected limbs. | ** Areflexia or decreased reflexes in affected limbs. | ||
Revision as of 18:50, 18 December 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.
Overview
Diagnostic Study of Choice
Diagnostic Criteria
- There is no single diagnostic study of choice for Guillain Barre syndrome, though GBS may be diagnosed based on NINDS criteria established by National Institute of Neurological Disorders and Stroke:[1][2]
- Progressive ascending weakness or paralysis usually starting from legs, involving are 4 limbs, the trunk, bulbar and facial muscles, and external ocular muscles.
- Areflexia or decreased reflexes in affected limbs.
- these findings can make the GBS diagnosis even more possible:
- Progression of symptoms over days to four weeks
- Relative symmetry
- Sensory abnormalities
- Cranial nerve involvement, especially bilateral facial nerve weakness
- Recovery starting two to four weeks after progression stops
- Autonomic disturbance
- Pain
- absence of fever in the acute phase
- Elevated CSF protein level
- CSF cell count ≤50/mm3
- Electrodiagnostic abnormalities consistent with GBS