Mantle cell lymphoma other diagnostic studies: Difference between revisions
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{{ Mantle cell lymphoma }} | {{Mantle cell lymphoma }} | ||
{{CMG}}; {{AE}} {{AS}} | {{CMG}}; {{AE}} {{AS}} | ||
==Overview== | ==Overview== | ||
Other diagnostic studies for the diagnosis of mantle cell lymphoma include [[bone marrow aspiration]], [[lumbar puncture]], [[colonoscopy]], [[upper endoscopy]], [[laparoscopy]], and [[laparotomy]]. | Other [[diagnostic]] studies for the [[diagnosis]] of [[mantle cell lymphoma]] include [[bone marrow aspiration]], [[lumbar puncture]], [[colonoscopy]], [[upper endoscopy]], [[laparoscopy]], and [[laparotomy]]. | ||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
Other diagnostic studies for the diagnosis of mantle cell lymphoma include: | Other [[diagnostic]] studies for the [[diagnosis]] of [[mantle cell lymphoma]] include: | ||
* [[Bone marrow aspiration]] | * [[Bone marrow aspiration]] | ||
* [[Lumbar puncture]] | * [[Lumbar puncture]] | ||
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* [[Laparotomy]] (rarely performed) | * [[Laparotomy]] (rarely performed) | ||
===Bone Marrow Aspiration=== | ===Bone Marrow Aspiration=== | ||
Mantle cell lymphoma is a systemic disease with frequent involvement of the bone marrow and the peripheral blood. There is also a not-uncommon leukemic phase, marked by presence in the blood. For this reason, both the peripheral blood and bone marrow are evaluated for the presence of malignant cells.<ref>{{Cite journal | [[Mantle cell lymphoma]] is a systemic disease with frequent involvement of the [[bone marrow]] and the [[peripheral blood]]. There is also a not-uncommon leukemic phase, marked by presence in the [[blood]]. For this reason, both the [[peripheral blood]] and [[bone marrow]] are evaluated for the presence of [[malignant]] cells.<ref>{{Cite journal | ||
| author = [[Daniel A. Arber]] & [[Tracy I. George]] | | author = [[Daniel A. Arber]] & [[Tracy I. George]] | ||
| title = Bone marrow biopsy involvement by non-Hodgkin's lymphoma: frequency of lymphoma types, patterns, blood involvement, and discordance with other sites in 450 specimens | | title = Bone marrow biopsy involvement by non-Hodgkin's lymphoma: frequency of lymphoma types, patterns, blood involvement, and discordance with other sites in 450 specimens | ||
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}}</ref> | }}</ref> | ||
===Lumbar Puncture=== | ===Lumbar Puncture=== | ||
In some patients with the blastic variant, lumbar puncture is done to evaluate the spinal fluid for CNS involvement.<ref>https://www.nccn.org/professionals/physician_gls/pdf/b-cell.pdf</ref> | In some patients with the blastic variant, [[lumbar puncture]] is done to evaluate the [[spinal fluid]] for [[CNS]] involvement.<ref>https://www.nccn.org/professionals/physician_gls/pdf/b-cell.pdf</ref> | ||
===Colonoscopy=== | ===Colonoscopy=== | ||
Since mantle cell lymphoma may present a lymphomatous polyposis coli and colon involvement is common, colonoscopy can be helpful in the diagnosis of MCL.<ref>https://www.nccn.org/professionals/physician_gls/pdf/b-cell.pdf</ref> | Since mantle cell lymphoma may present a lymphomatous polyposis coli and colon involvement is common, colonoscopy can be helpful in the diagnosis of MCL.<ref>https://www.nccn.org/professionals/physician_gls/pdf/b-cell.pdf</ref> | ||
===Upper Endoscopy=== | ===Upper Endoscopy=== | ||
Upper endoscopy may be helpful in selected cases. | [[Upper endoscopy]] may be helpful in selected cases. | ||
==References== | ==References== |
Revision as of 21:38, 18 December 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Other diagnostic studies for the diagnosis of mantle cell lymphoma include bone marrow aspiration, lumbar puncture, colonoscopy, upper endoscopy, laparoscopy, and laparotomy.
Other Diagnostic Studies
Other diagnostic studies for the diagnosis of mantle cell lymphoma include:
- Bone marrow aspiration
- Lumbar puncture
- Colonoscopy
- Upper endoscopy
- Laparoscopy (rarely performed)
- Laparotomy (rarely performed)
Bone Marrow Aspiration
Mantle cell lymphoma is a systemic disease with frequent involvement of the bone marrow and the peripheral blood. There is also a not-uncommon leukemic phase, marked by presence in the blood. For this reason, both the peripheral blood and bone marrow are evaluated for the presence of malignant cells.[1]
Lumbar Puncture
In some patients with the blastic variant, lumbar puncture is done to evaluate the spinal fluid for CNS involvement.[2]
Colonoscopy
Since mantle cell lymphoma may present a lymphomatous polyposis coli and colon involvement is common, colonoscopy can be helpful in the diagnosis of MCL.[3]
Upper Endoscopy
Upper endoscopy may be helpful in selected cases.
References
- ↑ Daniel A. Arber & Tracy I. George (2005). "Bone marrow biopsy involvement by non-Hodgkin's lymphoma: frequency of lymphoma types, patterns, blood involvement, and discordance with other sites in 450 specimens". The American journal of surgical pathology. 29 (12): 1549–1557. PMID 16327427. Unknown parameter
|month=
ignored (help) - ↑ https://www.nccn.org/professionals/physician_gls/pdf/b-cell.pdf
- ↑ https://www.nccn.org/professionals/physician_gls/pdf/b-cell.pdf