Guillain-Barré syndrome laboratory tests: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
* Laboratory findings consistent with the diagnosis of Guillain Barre syndrome include:<ref name="pmid22694000">{{cite journal |vauthors=Yuki N, Hartung HP |title=Guillain-Barré syndrome |journal=N. Engl. J. Med. |volume=366 |issue=24 |pages=2294–304 |date=June 2012 |pmid=22694000 |doi=10.1056/NEJMra1114525 |url=}}</ref><ref name="pmid14975602">{{cite journal |vauthors=Nishimoto Y, Odaka M, Hirata K, Yuki N |title=Usefulness of anti-GQ1b IgG antibody testing in Fisher syndrome compared with cerebrospinal fluid examination |journal=J. Neuroimmunol. |volume=148 |issue=1-2 |pages=200–5 |date=March 2004 |pmid=14975602 |doi=10.1016/j.jneuroim.2003.11.017 |url=}}</ref><ref name="pmid24163275">{{cite journal |vauthors=Fokke C, van den Berg B, Drenthen J, Walgaard C, van Doorn PA, Jacobs BC |title=Diagnosis of Guillain-Barré syndrome and validation of Brighton criteria |journal=Brain |volume=137 |issue=Pt 1 |pages=33–43 |date=January 2014 |pmid=24163275 |doi=10.1093/brain/awt285 |url=}}</ref><ref name="pmid8413947">{{cite journal |vauthors=Chiba A, Kusunoki S, Obata H, Machinami R, Kanazawa I |title=Serum anti-GQ1b IgG antibody is associated with ophthalmoplegia in Miller Fisher syndrome and Guillain-Barré syndrome: clinical and immunohistochemical studies |journal=Neurology |volume=43 |issue=10 |pages=1911–7 |date=October 1993 |pmid=8413947 |doi= |url=}}</ref> | * Laboratory findings consistent with the diagnosis of Guillain Barre syndrome include:<ref name="pmid22694000">{{cite journal |vauthors=Yuki N, Hartung HP |title=Guillain-Barré syndrome |journal=N. Engl. J. Med. |volume=366 |issue=24 |pages=2294–304 |date=June 2012 |pmid=22694000 |doi=10.1056/NEJMra1114525 |url=}}</ref><ref name="pmid14975602">{{cite journal |vauthors=Nishimoto Y, Odaka M, Hirata K, Yuki N |title=Usefulness of anti-GQ1b IgG antibody testing in Fisher syndrome compared with cerebrospinal fluid examination |journal=J. Neuroimmunol. |volume=148 |issue=1-2 |pages=200–5 |date=March 2004 |pmid=14975602 |doi=10.1016/j.jneuroim.2003.11.017 |url=}}</ref><ref name="pmid24163275">{{cite journal |vauthors=Fokke C, van den Berg B, Drenthen J, Walgaard C, van Doorn PA, Jacobs BC |title=Diagnosis of Guillain-Barré syndrome and validation of Brighton criteria |journal=Brain |volume=137 |issue=Pt 1 |pages=33–43 |date=January 2014 |pmid=24163275 |doi=10.1093/brain/awt285 |url=}}</ref><ref name="pmid8413947">{{cite journal |vauthors=Chiba A, Kusunoki S, Obata H, Machinami R, Kanazawa I |title=Serum anti-GQ1b IgG antibody is associated with ophthalmoplegia in Miller Fisher syndrome and Guillain-Barré syndrome: clinical and immunohistochemical studies |journal=Neurology |volume=43 |issue=10 |pages=1911–7 |date=October 1993 |pmid=8413947 |doi= |url=}}</ref> | ||
** Elevated CSF protein level. | ** Elevated [[CSF]] [[protein]] level. | ||
** Normal CSF WBC count. | ** Normal [[CSF]] [[WBC]] count. | ||
** Normal CSF cell count (in some cases there is mildly elevated cell count) | ** Normal [[CSF]] cell count (in some cases there is mildly elevated cell count) | ||
** Serum IgG antibody to GQ1b in Miller Fisher syndrome. | ** Serum [[Immunoglobulin G|IgG antibody]] to GQ1b in [[Miller Fisher syndrome]]. | ||
==References== | ==References== | ||
Revision as of 15:19, 27 December 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Priyamvada Singh, MBBS [2]
Overview
Laboratory Findings
- Laboratory findings consistent with the diagnosis of Guillain Barre syndrome include:[1][2][3][4]
- Elevated CSF protein level.
- Normal CSF WBC count.
- Normal CSF cell count (in some cases there is mildly elevated cell count)
- Serum IgG antibody to GQ1b in Miller Fisher syndrome.
References
- ↑ Yuki N, Hartung HP (June 2012). "Guillain-Barré syndrome". N. Engl. J. Med. 366 (24): 2294–304. doi:10.1056/NEJMra1114525. PMID 22694000.
- ↑ Nishimoto Y, Odaka M, Hirata K, Yuki N (March 2004). "Usefulness of anti-GQ1b IgG antibody testing in Fisher syndrome compared with cerebrospinal fluid examination". J. Neuroimmunol. 148 (1–2): 200–5. doi:10.1016/j.jneuroim.2003.11.017. PMID 14975602.
- ↑ Fokke C, van den Berg B, Drenthen J, Walgaard C, van Doorn PA, Jacobs BC (January 2014). "Diagnosis of Guillain-Barré syndrome and validation of Brighton criteria". Brain. 137 (Pt 1): 33–43. doi:10.1093/brain/awt285. PMID 24163275.
- ↑ Chiba A, Kusunoki S, Obata H, Machinami R, Kanazawa I (October 1993). "Serum anti-GQ1b IgG antibody is associated with ophthalmoplegia in Miller Fisher syndrome and Guillain-Barré syndrome: clinical and immunohistochemical studies". Neurology. 43 (10): 1911–7. PMID 8413947.