Sarcomatoid carcinoma of the lung historical perspective: Difference between revisions
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===Discovery=== | ===Discovery=== | ||
* | *Sarcomatoid carcinoma was first described by Virchow in 1865 as a “biphasic” lesion of [[Adenocarcinoma|adenocarcinomatous]] or [[squamous cell carcinoma]] with spindle cell or giant cell component.<ref>{{cite book |last=Virchow |first=Rudolf |date=1863 |title=Die KRANKHAFTEN GESCHWÜLSTE |volume=2 |url=https://collections.nlm.nih.gov/catalog/nlm:nlmuid-62231840R-mvset |access-date=1864}}</ref> | ||
*In 1981, World Health Organization (WHO) classification on lung cancers, mentioned pleomorphic carcinomas showing a prevalence of spindle or giant cells as morphologic variants of squamous cell carcinomas and large-cell carcinomas, respectively, and defined carcinosarcomas as biphasic tumors consisting of an intimate admixture of carcinoma and sarcoma.<ref name="pmid6978190">{{cite journal |vauthors=Sobin LH |title=The international histological classification of tumours |journal=Bull. World Health Organ. |volume=59 |issue=6 |pages=813–9 |date=1981 |pmid=6978190 |pmc=2396133 |doi= |url=}}</ref> | |||
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==Landmark Events in the Development of Treatment Strategies== | ==Landmark Events in the Development of Treatment Strategies== |
Revision as of 15:24, 31 December 2018
Sarcomatoid Carcinoma of the Lung Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Historical Perspective
Discovery
- Sarcomatoid carcinoma was first described by Virchow in 1865 as a “biphasic” lesion of adenocarcinomatous or squamous cell carcinoma with spindle cell or giant cell component.[1]
- In 1981, World Health Organization (WHO) classification on lung cancers, mentioned pleomorphic carcinomas showing a prevalence of spindle or giant cells as morphologic variants of squamous cell carcinomas and large-cell carcinomas, respectively, and defined carcinosarcomas as biphasic tumors consisting of an intimate admixture of carcinoma and sarcoma.[2]
Landmark Events in the Development of Treatment Strategies
Impact on Cultural History
Famous Cases
The following are a few famous cases of [disease name]:
References
- ↑ Virchow, Rudolf (1863). Die KRANKHAFTEN GESCHWÜLSTE. 2. Retrieved 1864. Check date values in:
|access-date=
(help) - ↑ Sobin LH (1981). "The international histological classification of tumours". Bull. World Health Organ. 59 (6): 813–9. PMC 2396133. PMID 6978190.