Phosphomevalonate kinase: Difference between revisions
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'''Phosphomevalonate kinase''' is an enzyme ({{EC number|2.7.4.2}}) in the mevalonate pathway.<ref>{{cite journal | | '''Phosphomevalonate kinase''' is an enzyme ({{EC number|2.7.4.2}}) in the mevalonate pathway.<ref>{{cite journal | vauthors = Bloch K, Chaykin S, Phillips AH, De Waard A | title = Mevalonic acid pyrophosphate and isopentenylpyrophosphate | journal = The Journal of Biological Chemistry | volume = 234 | pages = 2595–604 | date = October 1959 | pmid = 13801508 }}</ref><ref>{{cite journal | vauthors = Henning U, Moslein EM, Lynen F | title = Biosynthesis of terpenes. V. Formation of 5-pyrophosphomevalonic acid by phosphomevalonic kinase | journal = Archives of Biochemistry and Biophysics | volume = 83 | issue = 1 | pages = 259–67 | date = July 1959 | pmid = 13662013 | doi = 10.1016/0003-9861(59)90031-1 }}</ref><ref>{{cite journal | vauthors = Levy HR, Popjak G | title = Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver | journal = The Biochemical Journal | volume = 75 | pages = 417–28 | date = June 1960 | pmid = 14416398 | pmc = 1204488 | doi = 10.1042/bj0750417 }}</ref> | ||
[[Image:Mevalonate_pathway.png|350px|thumb|center|[[Mevalonate pathway]]]] | [[Image:Mevalonate_pathway.png|350px|thumb|center|[[Mevalonate pathway]]]] | ||
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==External links== | == External links == | ||
* {{MeshName|Phosphomevalonate+kinase}} | * {{MeshName|Phosphomevalonate+kinase}} | ||
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[[Category:EC 2.7.4]] | [[Category:EC 2.7.4]] | ||
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Latest revision as of 18:23, 10 February 2018
| Phosphomevalonate kinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.7.4.2 | ||||||||
| CAS number | 9026-46-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
| Phosphomevalonate kinase | |
|---|---|
| Identifiers | |
| Symbol | PMVK |
| Entrez | 10654 |
| HUGO | 9141 |
| OMIM | 607622 |
| RefSeq | NM_006556 |
| UniProt | Q15126 |
| Other data | |
| EC number | 2.7.4.2 |
| Locus | Chr. 1 p13-q23 |
Phosphomevalonate kinase is an enzyme (EC 2.7.4.2) in the mevalonate pathway.[1][2][3]
References
- ↑ Bloch K, Chaykin S, Phillips AH, De Waard A (October 1959). "Mevalonic acid pyrophosphate and isopentenylpyrophosphate". The Journal of Biological Chemistry. 234: 2595–604. PMID 13801508.
- ↑ Henning U, Moslein EM, Lynen F (July 1959). "Biosynthesis of terpenes. V. Formation of 5-pyrophosphomevalonic acid by phosphomevalonic kinase". Archives of Biochemistry and Biophysics. 83 (1): 259–67. doi:10.1016/0003-9861(59)90031-1. PMID 13662013.
- ↑ Levy HR, Popjak G (June 1960). "Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver". The Biochemical Journal. 75: 417–28. doi:10.1042/bj0750417. PMC 1204488. PMID 14416398.
External links
- Phosphomevalonate+kinase at the US National Library of Medicine Medical Subject Headings (MeSH)
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