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| ==Medical Therapy== | | ==Medical Therapy== |
| The optimal therapy for laryngeal cancer depends on the stage at the time of diagnosis. | | The medical therapy combined with [[radiation]] has largely replaced the surgical cure for [[laryngeal cancer]] depends on the stage at the time of [[diagnosis]].<ref name="pmid17453448">{{cite journal |vauthors=Tamura Y, Tanaka S, Asato R, Hirano S, Yamashita M, Tamaki H, Ito J |title=Therapeutic outcomes of laryngeal cancer at Kyoto University Hospital for 10 years |journal=Acta Otolaryngol Suppl |volume= |issue=557 |pages=62–5 |date=February 2007 |pmid=17453448 |doi=10.1080/00016480601067990 |url=}}</ref> |
| Treatment according to stages is as follows:<ref name=aaa>Treatment of laryngeal cancer according to stages. http://www.cancer.gov/types/head-and-neck/patient/laryngeal-treatment-pdq#section/_84</ref>
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| {| style="border: 0px; font-size: 90%; margin: 3px; width: 800px" align=center
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| |valign=top|
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| ! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Stage}}
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| ! style="background: #4479BA; width: 800px;" | {{fontcolor|#FFF|Treatment}}
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| | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center |
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| Stage 1
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| | style="padding: 5px 5px; background: #F5F5F5;" |
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| *If cancer is in the '''supraglottis''', treatment may include the following:
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| :*[[Radiation therapy]]
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| :*Supraglottic [[laryngectomy]]
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| *If cancer is in the '''glottis''', treatment may include the following:
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| :*Radiation therapy
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| :*Cordectomy
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| :*Partial laryngectomy, hemilaryngectomy, or total laryngectomy
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| :*Laser surgery
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| | |
| *If cancer is in the '''subglottis''', treatment may include the following:
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| :*Radiation therapy with or without surgery
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| :*Surgery alone
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| |- | |
| | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" align=center |
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| Stage 2
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| | style="padding: 5px 5px; background: #F5F5F5;" |
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| *If cancer is in the '''supraglottis''', treatment may include the following:
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| :*Radiation therapy
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| :*Supraglottic laryngectomy or total laryngectomy with or without radiation therapy
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| | |
| *If cancer is in the '''glottis''', treatment may include the following:
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| :*Radiation therapy
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| :*Partial laryngectomy, hemilaryngectomy, or total laryngectomy
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| :*Laser surgery
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| :*A clinical trial of radiation therapy
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| :*A clinical trial of chemoprevention
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| | |
| *If cancer is in the '''subglottis''', treatment may include the following:
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| :*Radiation therapy with or without surgery
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| :*Surgery alone
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| :*A clinical trial of radiation therapy
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| :*A clinical trial of chemoprevention
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| |- | |
| | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center| | |
| Stage 3
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| | style="padding: 5px 5px; background: #F5F5F5;" | | |
| *If cancer is in the '''supraglottis''' or '''glottis''', treatment may include the following:
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| :*Chemotherapy and radiation therapy given together
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| :*Chemotherapy followed by chemotherapy and radiation therapy given together
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| :*Laryngectomy may be done if cancer remains
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| :*Radiation therapy for patients who cannot be treated with chemotherapy and surgery
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| :*For tumors that do not respond to radiation, total laryngectomy may be done
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| :*Surgery, which may be followed by radiation therapy
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| :*A clinical trial of radiation therapy
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| :*A clinical trial of chemotherapy, radiosensitizers, or radiation therapy
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| :*A clinical trial of chemoprevention
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| | |
| *If cancer is in the '''subglottis''', treatment may include the following:
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| :*Laryngectomy plus total thyroidectomy and removal of lymph nodes in the throat, usually followed by radiation therapy
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| :*Radiation therapy with or without surgery
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| :*A clinical trial of chemotherapy, radiosensitizers, or radiation therapy
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| :*A clinical trial of chemoprevention
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| |- | |
| | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center|
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| Stage 4
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| | style="padding: 5px 5px; background: #F5F5F5;" | | |
| *If cancer is in the '''supraglottis''' or '''glottis''', treatment may include the following:
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| :*Chemotherapy and radiation therapy given together
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| :*Chemotherapy followed by chemotherapy and radiation therapy given together
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| :*Laryngectomy may be done if cancer remains
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| :*Radiation therapy for patients who cannot be treated with chemotherapy and surgery
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| :*For tumors that do not respond to radiation, total laryngectomy may be done
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| :*Surgery followed by radiation therapy
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| :*Chemotherapy may be given with the radiation therapy
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| :*A clinical trial of radiation therapy
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| :*A clinical trial of chemotherapy, radiosensitizers, or radiation therapy
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| :*A clinical trial of chemoprevention
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| | |
| *If cancer is in the '''subglottis''', treatment may include the following:
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| :*Laryngectomy plus total thyroidectomy and removal of lymph nodes in the throat, usually with radiation therapy
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| :*Radiation therapy
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| :*A clinical trial of radiation therapy
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| :*A clinical trial of chemotherapy, radiosensitizers, or radiation therapy
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| :*A clinical trial of chemoprevention
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| |-
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| |}
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| ==Supportive Treatment== | | ==Supportive Treatment== |
| Many patients also need swallowing rehabilitation after treatment to help them adjust to the changes in the structure of the throat. | | Many patients also need swallowing rehabilitation after treatment to help them adjust to the changes in the structure of the throat. |