Rhabdomyosarcoma risk factors: Difference between revisions
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** Low socio-economic situations | ** Low socio-economic situations | ||
** Anti-biotic therapy soon after birth | ** Anti-biotic therapy soon after birth | ||
** In children whose parents took recreational drugs during pregnancy<ref name="pmid8318638">{{cite journal| author=Grufferman S, Schwartz AG, Ruymann FB, Maurer HM| title=Parents' use of cocaine and marijuana and increased risk of rhabdomyosarcoma in their children. | journal=Cancer Causes Control | year= 1993 | volume= 4 | issue= 3 | pages= 217-24 | pmid=8318638 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8318638 }} </ref> | ** In children whose parents took recreational drugs such as [[cocaine]] and [[marijuana]]during pregnancy<ref name="pmid8318638">{{cite journal| author=Grufferman S, Schwartz AG, Ruymann FB, Maurer HM| title=Parents' use of cocaine and marijuana and increased risk of rhabdomyosarcoma in their children. | journal=Cancer Causes Control | year= 1993 | volume= 4 | issue= 3 | pages= 217-24 | pmid=8318638 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8318638 }} </ref> | ||
**Accelerated growth in utero | **Accelerated growth in utero | ||
*Rhabdomyosarcomamay be associated with following familial syndroms:<ref name="pmid5360287">{{cite journal| author=Li FP, Fraumeni JF| title=Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome? | journal=Ann Intern Med | year= 1969 | volume= 71 | issue= 4 | pages= 747-52 | pmid=5360287 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=5360287 }} </ref><ref name="pmid3155239">{{cite journal| author=Hartley AL, Birch JM, Marsden HB, Harris M, Blair V| title=Neurofibromatosis in children with soft tissue sarcoma. | journal=Pediatr Hematol Oncol | year= 1988 | volume= 5 | issue= 1 | pages= 7-16 | pmid=3155239 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3155239 }} </ref><ref name="pmid9544889">{{cite journal| author=DeBaun MR, Tucker MA| title=Risk of cancer during the first four years of life in children from The Beckwith-Wiedemann Syndrome Registry. | journal=J Pediatr | year= 1998 | volume= 132 | issue= 3 Pt 1 | pages= 398-400 | pmid=9544889 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9544889 }} </ref> | |||
*[[Beckwith-Wiedemann syndrome]] | **[[Beckwith-Wiedemann syndrome]]<ref name="pmid11826361">{{cite journal| author=Smith AC, Squire JA, Thorner P, Zielenska M, Shuman C, Grant R et al.| title=Association of alveolar rhabdomyosarcoma with the Beckwith-Wiedemann syndrome. | journal=Pediatr Dev Pathol | year= 2001 | volume= 4 | issue= 6 | pages= 550-8 | pmid=11826361 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11826361 }} </ref> | ||
*[[Li-Fraumeni syndrome]] | **[[Li-Fraumeni syndrome]] | ||
*[[Costello syndrome]] | **[[Costello syndrome]]<ref name="pmid18025929">{{cite journal| author=Quezada E, Gripp KW| title=Costello syndrome and related disorders. | journal=Curr Opin Pediatr | year= 2007 | volume= 19 | issue= 6 | pages= 636-44 | pmid=18025929 | doi=10.1097/MOP.0b013e3282f161dc | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18025929 }} </ref> | ||
* | ** Neurofibromatosis<ref name="pmid8402499">{{cite journal| author=Matsui I, Tanimura M, Kobayashi N, Sawada T, Nagahara N, Akatsuka J| title=Neurofibromatosis type 1 and childhood cancer. | journal=Cancer | year= 1993 | volume= 72 | issue= 9 | pages= 2746-54 | pmid=8402499 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8402499 }} </ref> | ||
* | |||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
The common risk factors in the development of rhabdomyosarcoma are Beckwith-Wiedemann syndrome, Li-Fraumeni syndrome, Costello syndrome, and Noonan syndrome.
Risk Factors
- The same as all other childhood cancers, the particular risk factors of rhabdomyosarcoma is not exactly known.[1]
- Higher incidence of rhabdomyosarcoma is reported among following individuals:[2][3][4]
- Exposure to radiation in utero
- Low socio-economic situations
- Anti-biotic therapy soon after birth
- In children whose parents took recreational drugs such as cocaine and marijuanaduring pregnancy[5]
- Accelerated growth in utero
- Rhabdomyosarcomamay be associated with following familial syndroms:[6][7][8]
- Beckwith-Wiedemann syndrome[9]
- Li-Fraumeni syndrome
- Costello syndrome[10]
- Neurofibromatosis[11]
References
- ↑ Grufferman S, Wang HH, DeLong ER, Kimm SY, Delzell ES, Falletta JM (1982). "Environmental factors in the etiology of rhabdomyosarcoma in childhood". J Natl Cancer Inst. 68 (1): 107–13. PMID 6948120.
- ↑ Magnani C, Pastore G, Luzzatto L, Carli M, Lubrano P, Terracini B (1989). "Risk factors for soft tissue sarcomas in childhood: a case-control study". Tumori. 75 (4): 396–400. PMID 2815346.
- ↑ Hartley AL, Birch JM, McKinney PA, Teare MD, Blair V, Carrette J; et al. (1988). "The Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC): case control study of children with bone and soft tissue sarcomas". Br J Cancer. 58 (6): 838–42. PMC 2246858. PMID 3224086.
- ↑ Ognjanovic S, Carozza SE, Chow EJ, Fox EE, Horel S, McLaughlin CC; et al. (2010). "Birth characteristics and the risk of childhood rhabdomyosarcoma based on histological subtype". Br J Cancer. 102 (1): 227–31. doi:10.1038/sj.bjc.6605484. PMC 2813761. PMID 19997102.
- ↑ Grufferman S, Schwartz AG, Ruymann FB, Maurer HM (1993). "Parents' use of cocaine and marijuana and increased risk of rhabdomyosarcoma in their children". Cancer Causes Control. 4 (3): 217–24. PMID 8318638.
- ↑ Li FP, Fraumeni JF (1969). "Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome?". Ann Intern Med. 71 (4): 747–52. PMID 5360287.
- ↑ Hartley AL, Birch JM, Marsden HB, Harris M, Blair V (1988). "Neurofibromatosis in children with soft tissue sarcoma". Pediatr Hematol Oncol. 5 (1): 7–16. PMID 3155239.
- ↑ DeBaun MR, Tucker MA (1998). "Risk of cancer during the first four years of life in children from The Beckwith-Wiedemann Syndrome Registry". J Pediatr. 132 (3 Pt 1): 398–400. PMID 9544889.
- ↑ Smith AC, Squire JA, Thorner P, Zielenska M, Shuman C, Grant R; et al. (2001). "Association of alveolar rhabdomyosarcoma with the Beckwith-Wiedemann syndrome". Pediatr Dev Pathol. 4 (6): 550–8. PMID 11826361.
- ↑ Quezada E, Gripp KW (2007). "Costello syndrome and related disorders". Curr Opin Pediatr. 19 (6): 636–44. doi:10.1097/MOP.0b013e3282f161dc. PMID 18025929.
- ↑ Matsui I, Tanimura M, Kobayashi N, Sawada T, Nagahara N, Akatsuka J (1993). "Neurofibromatosis type 1 and childhood cancer". Cancer. 72 (9): 2746–54. PMID 8402499.