Hemophilia history and symptoms: Difference between revisions
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Patients with hemophilia may have a positive history of: | Patients with hemophilia may have a positive history of: | ||
*Easy bruising<ref name="pmid30129541">{{cite journal |vauthors=Sachdeva A, Gunasekaran V, Ramya HN, Dass J, Kotwal J, Seth T, Das S, Garg K, Kalra M, Sirisha RS, Prakash A |title=Consensus Statement of the Indian Academy of Pediatrics in Diagnosis and Management of Hemophilia |journal=Indian Pediatr |volume=55 |issue=7 |pages=582–590 |date=July 2018 |pmid=30129541 |doi= |url=}}</ref> | *Easy bruising<ref name="pmid30129541">{{cite journal |vauthors=Sachdeva A, Gunasekaran V, Ramya HN, Dass J, Kotwal J, Seth T, Das S, Garg K, Kalra M, Sirisha RS, Prakash A |title=Consensus Statement of the Indian Academy of Pediatrics in Diagnosis and Management of Hemophilia |journal=Indian Pediatr |volume=55 |issue=7 |pages=582–590 |date=July 2018 |pmid=30129541 |doi= |url=}}</ref> | ||
*Prolonged excessive bleeds following surgery or trauma<ref name="pmid30129541">{{cite journal |vauthors=Sachdeva A, Gunasekaran V, Ramya HN, Dass J, Kotwal J, Seth T, Das S, Garg K, Kalra M, Sirisha RS, Prakash A |title=Consensus Statement of the Indian Academy of Pediatrics in Diagnosis and Management of Hemophilia |journal=Indian Pediatr |volume=55 |issue=7 |pages=582–590 |date=July 2018 |pmid=30129541 |doi= |url=}}</ref> | |||
*Unprovoked deep-seated bleeds<ref name="pmid30129541">{{cite journal |vauthors=Sachdeva A, Gunasekaran V, Ramya HN, Dass J, Kotwal J, Seth T, Das S, Garg K, Kalra M, Sirisha RS, Prakash A |title=Consensus Statement of the Indian Academy of Pediatrics in Diagnosis and Management of Hemophilia |journal=Indian Pediatr |volume=55 |issue=7 |pages=582–590 |date=July 2018 |pmid=30129541 |doi= |url=}}</ref> | *Unprovoked deep-seated bleeds<ref name="pmid30129541">{{cite journal |vauthors=Sachdeva A, Gunasekaran V, Ramya HN, Dass J, Kotwal J, Seth T, Das S, Garg K, Kalra M, Sirisha RS, Prakash A |title=Consensus Statement of the Indian Academy of Pediatrics in Diagnosis and Management of Hemophilia |journal=Indian Pediatr |volume=55 |issue=7 |pages=582–590 |date=July 2018 |pmid=30129541 |doi= |url=}}</ref> | ||
* | *Patients with hemarthroses can present with: | ||
* | :*Joint motion limitation<ref name="BerntorpShapiro2012">{{cite journal|last1=Berntorp|first1=Erik|last2=Shapiro|first2=Amy D|title=Modern haemophilia care|journal=The Lancet|volume=379|issue=9824|year=2012|pages=1447–1456|issn=01406736|doi=10.1016/S0140-6736(11)61139-2}}</ref> | ||
:*Pain, and discomfort<ref name="BerntorpShapiro2012">{{cite journal|last1=Berntorp|first1=Erik|last2=Shapiro|first2=Amy D|title=Modern haemophilia care|journal=The Lancet|volume=379|issue=9824|year=2012|pages=1447–1456|issn=01406736|doi=10.1016/S0140-6736(11)61139-2}}</ref><ref name="FranchiniMannucci2013">{{cite journal|last1=Franchini|first1=Massimo|last2=Mannucci|first2=Pier Mannuccio|title=Hemophilia A in the third millennium|journal=Blood Reviews|volume=27|issue=4|year=2013|pages=179–184|issn=0268960X|doi=10.1016/j.blre.2013.06.002}}</ref> | |||
:*Cutaneous warmth<ref name="FranchiniMannucci2013">{{cite journal|last1=Franchini|first1=Massimo|last2=Mannucci|first2=Pier Mannuccio|title=Hemophilia A in the third millennium|journal=Blood Reviews|volume=27|issue=4|year=2013|pages=179–184|issn=0268960X|doi=10.1016/j.blre.2013.06.002}}</ref> | |||
:*Joint swelling<ref name="FranchiniMannucci2013">{{cite journal|last1=Franchini|first1=Massimo|last2=Mannucci|first2=Pier Mannuccio|title=Hemophilia A in the third millennium|journal=Blood Reviews|volume=27|issue=4|year=2013|pages=179–184|issn=0268960X|doi=10.1016/j.blre.2013.06.002}}</ref> | |||
==References== | ==References== | ||
Revision as of 15:20, 18 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Patients with hemophilia can present with a history of excessive bleeding after minor injuries or spontaneous bleeding. They can also report family history of hemophilia. Hemophilia when mild, can be asymptomatic. Common symptoms, when present, include epistaxis, oral mucosal bleeding, joint pain and swelling, lethargy and fatigue, excessive bleeding after dental procedures, prolonged bleeding after circumcision and muscle hematoma after vaccination.
History and Symptoms
Patients with hemophilia may have a positive history of:
- Easy bruising[1]
- Prolonged excessive bleeds following surgery or trauma[1]
- Unprovoked deep-seated bleeds[1]
- Patients with hemarthroses can present with:
References
- ↑ 1.0 1.1 1.2 Sachdeva A, Gunasekaran V, Ramya HN, Dass J, Kotwal J, Seth T, Das S, Garg K, Kalra M, Sirisha RS, Prakash A (July 2018). "Consensus Statement of the Indian Academy of Pediatrics in Diagnosis and Management of Hemophilia". Indian Pediatr. 55 (7): 582–590. PMID 30129541.
- ↑ 2.0 2.1 Berntorp, Erik; Shapiro, Amy D (2012). "Modern haemophilia care". The Lancet. 379 (9824): 1447–1456. doi:10.1016/S0140-6736(11)61139-2. ISSN 0140-6736.
- ↑ 3.0 3.1 3.2 Franchini, Massimo; Mannucci, Pier Mannuccio (2013). "Hemophilia A in the third millennium". Blood Reviews. 27 (4): 179–184. doi:10.1016/j.blre.2013.06.002. ISSN 0268-960X.