Cervical cancer differential diagnosis: Difference between revisions
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|- style="background: #4479BA; color: #FFFFFF; text-align: center;" | |- style="background: #4479BA; color: #FFFFFF; text-align: center;" | ||
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases | ! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases | ||
| colspan=" | | colspan="10" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Clinical manifestations''' | ||
! colspan="8" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para-clinical findings | ! colspan="8" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para-clinical findings | ||
| colspan="1" rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Gold standard''' | | colspan="1" rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Gold standard''' | ||
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Additional findings | ! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Additional findings | ||
|- | |- | ||
! colspan=" | ! colspan="9" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptoms | ||
! | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam | ||
! colspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings | ! colspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings | ||
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging | ! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging | ||
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology | ! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology | ||
|- | |- | ||
! style="background: #4479BA; color: #FFFFFF; text-align: center;" | | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Abnormal vaginal bleeding | ||
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Abnormal vaginal dyscharge | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Abnormal vaginal dyscharge | ||
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Pelvic pain or pressure | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Pelvic pain or pressure | ||
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! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Swollen lymph nodes | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Swollen lymph nodes | ||
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Weight loss | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Weight loss | ||
! style="background: #4479BA; color: #FFFFFF; text-align: center;" | | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gynecological examinations | ||
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |HPV | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |HPV | ||
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Pap smear | ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Pap smear | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervical cancer | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervical cancer | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | + | |||
| style="background: #F5F5F5; padding: 5px;" | + | |||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervical polyp | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervical polyp | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
* Postcoital bleeding | |||
* Intermenstrual bleeding | |||
* Postmenopausal bleeding | |||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| | |||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervical leiomyoma | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervical leiomyoma | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervical lymphoma | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervical lymphoma | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervical sarcoma | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervical sarcoma | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervical erosion(Ectropion) | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervical erosion(Ectropion) | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervicitis | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Cervicitis | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |IUD use | | style="background: #DCDCDC; padding: 5px; text-align: center;" |IUD use | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Pelvic inflammatory diseases | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Pelvic inflammatory diseases | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Endometriosis | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Endometriosis | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Adnemyosis | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Adnemyosis | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Postcoital bleeding | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Postcoital bleeding | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |DES exposure (Clear cell adenocarcinoma) | | style="background: #DCDCDC; padding: 5px; text-align: center;" |DES exposure (Clear cell adenocarcinoma) | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Paget's disease of vulva | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Paget's disease of vulva | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" |Vaginal cancer | | style="background: #DCDCDC; padding: 5px; text-align: center;" |Vaginal cancer | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | |
Revision as of 20:29, 24 January 2019
Cervical cancer Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Cervical cancer differential diagnosis On the Web |
American Roentgen Ray Society Images of Cervical cancer differential diagnosis |
Risk calculators and risk factors for Cervical cancer differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]
Overview
Cervical cancer must be differentiated from other diseases that cause abnormal vaginal bleeding, such as cervical polyp, cervical leiomyoma, invasion of the cervix from primary uterine malignancy, vaginal cancer, cervical lymphoma, metastases to cervix, and cervical ectopic pregnancy.
Cervical cancer differential diagnosis
- Cervical cancer must be differentiated from a mass involving the cervix, and causing abnormal vaginal bleeding:
- Cervical polyp
- Cervical leiomyoma
- Cervical lymphoma
- Cervical sarcoma
- Metastases to the cervix
- Cervical ectopic pregnancy
- Cervical polyp
- Cervicitis
- Cervical erosion ( Ectropion )
- IUD use
- Pelvic inflammatory disease
- Endometriosis
- Adenomyosis
- Postcoital bleeding
- Clear cell adenocarcinoma
Diseases | Clinical manifestations | Para-clinical findings | Gold standard | Additional findings | |||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Symptoms | Physical exam | Lab Findings | Imaging | Histopathology | |||||||||||||||||||||
Abnormal vaginal bleeding | Abnormal vaginal dyscharge | Pelvic pain or pressure | Itching or burning of the vulva | Vaginal/vulvar sores or change in color | Abdominal pain | Fever | Swollen lymph nodes | Weight loss | Gynecological examinations | HPV | Pap smear | STI Panel | Coagulation studies | Imaging 1 | Imaging 2 | Imaging 3 | |||||||||
Cervical cancer | + | + | |||||||||||||||||||||||
Cervical polyp |
|
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Cervical leiomyoma | |||||||||||||||||||||||||
Cervical lymphoma | |||||||||||||||||||||||||
Cervical sarcoma | |||||||||||||||||||||||||
Cervical erosion(Ectropion) | |||||||||||||||||||||||||
Cervicitis | |||||||||||||||||||||||||
IUD use | |||||||||||||||||||||||||
Pelvic inflammatory diseases | |||||||||||||||||||||||||
Endometriosis | |||||||||||||||||||||||||
Adnemyosis | |||||||||||||||||||||||||
Postcoital bleeding | |||||||||||||||||||||||||
DES exposure (Clear cell adenocarcinoma) | |||||||||||||||||||||||||
Paget's disease of vulva | |||||||||||||||||||||||||
Vaginal cancer |