Cervical cancer differential diagnosis: Difference between revisions

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|- style="background: #4479BA; color: #FFFFFF; text-align: center;"
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
| colspan="10" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Clinical manifestations'''
| colspan="11" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Clinical manifestations'''
! colspan="8" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para-clinical findings
! colspan="8" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para-clinical findings
| colspan="1" rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Gold standard'''
| colspan="1" rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Gold standard'''
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Additional findings
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Additional findings
|-
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! colspan="9" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptoms
! colspan="10" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptoms
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam
! colspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings
! colspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings
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! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Itching or burning of the vulva
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Itching or burning of the vulva
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Vaginal/vulvar sores or change in color  
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Vaginal/vulvar sores or change in color  
!Genitourinary symptoms
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Abdominal pain
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Abdominal pain
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
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* Dysuria
* Difficulty urinating
* Pain during sex
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Revision as of 15:33, 25 January 2019

Cervical cancer Microchapters

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Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Cervical Cancer from other Diseases

Epidemiology and Demographics

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Diagnostic Study of Choice

History and Symptoms

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Cervical Cancer During Pregnancy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]

Overview

Cervical cancer must be differentiated from other diseases that cause abnormal vaginal bleeding, such as cervical polyp, cervical leiomyoma, invasion of the cervix from primary uterine malignancy, vaginal cancer, cervical lymphoma, metastases to cervix, and cervical ectopic pregnancy.

Cervical cancer differential diagnosis

  • Cervical cancer must be differentiated from a mass involving the cervix, and causing abnormal vaginal bleeding:
  • Metastases to the cervix
  • Cervical ectopic pregnancy
  • Cervical polyp
  • Cervicitis
  • Cervical erosion ( Ectropion )
  • IUD use
  • Pelvic inflammatory disease
  • Endometriosis
  • Adenomyosis
  • Postcoital bleeding
  • Clear cell adenocarcinoma
Diseases Clinical manifestations Para-clinical findings Gold standard Additional findings
Symptoms Physical exam Lab Findings Imaging Histopathology
Abnormal vaginal bleeding Abnormal vaginal dyscharge Pelvic pain or pressure Itching or burning of the vulva Vaginal/vulvar sores or change in color Genitourinary symptoms Abdominal pain Fever Swollen lymph nodes Weight loss Gynecological examinations HPV Pap smear STI Panel Coagulation studies Imaging 1 Imaging 2 Imaging 3
Cervical cancer
  • Postmenopausal
  • Intermenstrual
  • Postcoital
  • Bleeding after pelvic exam
 + + + −
  • Dysuria
  • Difficulty urinating
  • Pain during sex

+

+ + +
Cervical polyp
  • Postcoital
  • Intermenstrual
  • Postmenopausal
  • Bleeding after exam
Cervical leiomyoma[1]
  • Heavy/prolonged menstrual bleeding
  • Intermenstrual bleeding
Cervical lymphoma[2]
  • Postmenopausal bleeding
Cervical sarcoma[3]
  • Intermentrual
  • Postmenopausal
Cervical erosion(Ectropion)
  • Light bleeding after pelvic exam
  • Spotting
Cervicitis
IUD use
Pelvic inflammatory diseases
Endometriosis
Adnemyosis
Postcoital bleeding
DES exposure (Clear cell adenocarcinoma)
Paget's disease of vulva
Vaginal cancer

References

  1. ↑ Al-Habib A, Elgamal EA, Aldhahri S, Alokaili R, AlShamrani R, Abobotain A, AlRaddadi K, Alkhalidi H (November 2016). "Large primary leiomyoma causing progressive cervical deformity". J Surg Case Rep. 2016 (11). doi:10.1093/jscr/rjw190. PMC 5159177. PMID 27887011.
  2. ↑ Grace A, O'Connell N, Byrne P, Prendiville W, O'Donnell R, Royston D, Walsh CB, Leader M, Kay E (1999). "Malignant lymphoma of the cervix. An unusual presentation and a rare disease". Eur. J. Gynaecol. Oncol. 20 (1): 26–8. PMID 10422676.
  3. ↑ Wright JD, Rosenblum K, Huettner PC, Mutch DG, Rader JS, Powell MA, Gibb RK (November 2005). "Cervical sarcomas: an analysis of incidence and outcome". Gynecol. Oncol. 99 (2): 348–51. doi:10.1016/j.ygyno.2005.06.021. PMID 16051326.

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