Folate deficiency history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
History plays an important role in folate deficiency as the signs and symptoms associated with it are subtle and non specific. | |||
==History and Symptoms== | ==History and Symptoms== |
Revision as of 03:58, 30 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
History plays an important role in folate deficiency as the signs and symptoms associated with it are subtle and non specific.
History and Symptoms
Late studies suggested an involvement in tumorogenesis (especially in colon) through demethylation/hypomethylation of fast replicating tissues.
History
History presents a pivotal role in determining the causative agent of the folate deficiency anemia.The patients of folate deficiency anemia may present with a positive history of:
- Pregnancy or Lactation
- Malabsorption
- Decreased dietary intake
- Chronic disease like history of chronic hemolytic anemia or Exfoliative dermatitis
- Excessive alcohol intake
- Use of certain medication like Methotrexate, Phenytoin and Sulphonamide,Trimethoprim
- history of chronic renal failure on hemodialysis
Common symptoms
- Sore tongue
- Anorexia
- Slow growth rate
- Depression
- Dementia
- premature and low birth weight infacts born to pregnant lady with folate deficiency
Less common symptoms
- Diarrhea
- Weight loss
- Nausea
- Vomiting
- Abdominal pain