Rhabdomyosarcoma other diagnostic studies: Difference between revisions
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===Biopsy=== | ===Biopsy=== | ||
* Tissue biopsy considered as most commonly diagnosis in rhabdomyosarcoma.<ref name="pmid19418540">{{cite journal| author=Chowdhury T, Barnacle A, Haque S, Sebire N, Gibson S, Anderson J et al.| title=Ultrasound-guided core needle biopsy for the diagnosis of rhabdomyosarcoma in childhood. | journal=Pediatr Blood Cancer | year= 2009 | volume= 53 | issue= 3 | pages= 356-60 | pmid=19418540 | doi=10.1002/pbc.22059 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19418540 }} </ref> | * Tissue biopsy considered as most commonly diagnosis in rhabdomyosarcoma.<ref name="pmid19418540">{{cite journal| author=Chowdhury T, Barnacle A, Haque S, Sebire N, Gibson S, Anderson J et al.| title=Ultrasound-guided core needle biopsy for the diagnosis of rhabdomyosarcoma in childhood. | journal=Pediatr Blood Cancer | year= 2009 | volume= 53 | issue= 3 | pages= 356-60 | pmid=19418540 | doi=10.1002/pbc.22059 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19418540 }} </ref> | ||
* There are several ways of taking biopsies which depends on following criteria:<ref name="pmid24599626">{{cite journal| author=Nunez AL, Elgin JN, Fatima H| title=Fine-needle aspiration biopsy of alveolar rhabdomyosarcoma of Stensen's duct: a case report and review of the literature. | journal=Diagn Cytopathol | year= 2014 | volume= 42 | issue= 12 | pages= 1069-74 | pmid=24599626 | doi=10.1002/dc.23084 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24599626 }} </ref><ref>Kaseb H, Babiker HM. Cancer, Rhabdomyosarcoma. [Updated 2018 Oct 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507721/</ref> | * There are several ways of taking biopsies which depends on following criteria:<ref name="pmid24599626">{{cite journal| author=Nunez AL, Elgin JN, Fatima H| title=Fine-needle aspiration biopsy of alveolar rhabdomyosarcoma of Stensen's duct: a case report and review of the literature. | journal=Diagn Cytopathol | year= 2014 | volume= 42 | issue= 12 | pages= 1069-74 | pmid=24599626 | doi=10.1002/dc.23084 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24599626 }} </ref><ref name=":0">Kaseb H, Babiker HM. Cancer, Rhabdomyosarcoma. [Updated 2018 Oct 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507721/</ref> | ||
** Patients's age | ** Patients's age | ||
** Primary site of tumor | ** Primary site of tumor | ||
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* Also may be considered as a diagnostic study in rhabdomyosarcomas with meningeal involvement. | * Also may be considered as a diagnostic study in rhabdomyosarcomas with meningeal involvement. | ||
=== Bone marrow aspiration and biopsy=== | === Bone marrow aspiration and biopsy=== | ||
* Bone marrow aspiration is usually performed for evaluation of bone marrow involvement due to metastases. | * Bone marrow aspiration is usually performed for evaluation of bone marrow involvement due to metastases.<ref name=":0" /><ref name="pmid23940218" /> | ||
* The samples are taken from pelvic bones. | * The samples are taken from pelvic bones. | ||
* It is considered as low yield diagnostic study. | * It is considered as low yield diagnostic study. | ||
Revision as of 16:51, 8 February 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]
Overview
No additional tests are recommended for the diagnosis of rhabdomyosarcoma.
Other Diagnostic Tests
Biopsy
- Tissue biopsy considered as most commonly diagnosis in rhabdomyosarcoma.[1]
- There are several ways of taking biopsies which depends on following criteria:[2][3]
- Patients's age
- Primary site of tumor
- Open surgical biopsy is considered as a recommended method to obtaining tissues and proper diagnosis.[4]
- Needle biopsies are considered as less invasive way of taking biopsies.
- Core-needle biopsy
- Fine- needle biopsy
Lumbar puncture
- Lumbar puncture is considered as unnecessary procedure in rhabdomyosarcoma diagnosis.[5]
- Lumbar puncture is usually done in parameningeal rhabdomyosarcoma.
- Also may be considered as a diagnostic study in rhabdomyosarcomas with meningeal involvement.
Bone marrow aspiration and biopsy
- Bone marrow aspiration is usually performed for evaluation of bone marrow involvement due to metastases.[3][5]
- The samples are taken from pelvic bones.
- It is considered as low yield diagnostic study.
References
- ↑ Chowdhury T, Barnacle A, Haque S, Sebire N, Gibson S, Anderson J; et al. (2009). "Ultrasound-guided core needle biopsy for the diagnosis of rhabdomyosarcoma in childhood". Pediatr Blood Cancer. 53 (3): 356–60. doi:10.1002/pbc.22059. PMID 19418540.
- ↑ Nunez AL, Elgin JN, Fatima H (2014). "Fine-needle aspiration biopsy of alveolar rhabdomyosarcoma of Stensen's duct: a case report and review of the literature". Diagn Cytopathol. 42 (12): 1069–74. doi:10.1002/dc.23084. PMID 24599626.
- ↑ 3.0 3.1 Kaseb H, Babiker HM. Cancer, Rhabdomyosarcoma. [Updated 2018 Oct 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507721/
- ↑ PDQ Pediatric Treatment Editorial Board. Childhood Rhabdomyosarcoma Treatment (PDQ®): Patient Version. 2019 Jan 30. In: PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK65839/
- ↑ 5.0 5.1 Weiss AR, Lyden ER, Anderson JR, Hawkins DS, Spunt SL, Walterhouse DO; et al. (2013). "Histologic and clinical characteristics can guide staging evaluations for children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee". J Clin Oncol. 31 (26): 3226–32. doi:10.1200/JCO.2012.44.6476. PMC 3757291. PMID 23940218.