Folate deficiency classification: Difference between revisions
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==Overview== | ==Overview== | ||
There is no established system for the classification of Folate deficiency. However | There is no established system for the classification of Folate deficiency. However, it can be classified into different categories,based on the causative factors. | ||
==Classification== | ==Classification== | ||
Folate deficiency can be classified as follows : | There is no established system for the classification of Folate deficiency. However, it can be classified as follows : | ||
=== | ===Folate deficiency related to increased requirement:=== | ||
Some situations that increase the need for folate may lead to folate deficiency in the body. These include: | Some situations that increase the need for folate, may lead to folate deficiency in the body. These include: | ||
*Hemorrhage | *Hemorrhage | ||
*Kidney dialysis | *Kidney dialysis | ||
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*Pregnancy and lactation | *Pregnancy and lactation | ||
*Alcohol consumption | *Alcohol consumption | ||
=== | ===Medication induced Folate Deficiency:=== | ||
Medications can interfere with folate utilization, including: | Medications can interfere with folate utilization, including: | ||
*Anticonvulsant medications e.g phenytoin | *Anticonvulsant medications e.g phenytoin | ||
| Line 24: | Line 24: | ||
*Sulfasalazine, used in Inflammatory bowel syndrome | *Sulfasalazine, used in Inflammatory bowel syndrome | ||
*Birth control pills | *Birth control pills | ||
=== | ===Genetic or Metabolic disorder:=== | ||
*Defects in folate metabolism | *Defects in folate metabolism | ||
*Defects in folate absorption | *Defects in folate absorption | ||
=== Dietary Deficiency: === | |||
* A diet low in fresh fruits, vegetables, and fortified cereals | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 03:45, 12 February 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
There is no established system for the classification of Folate deficiency. However, it can be classified into different categories,based on the causative factors.
Classification
There is no established system for the classification of Folate deficiency. However, it can be classified as follows :
Some situations that increase the need for folate, may lead to folate deficiency in the body. These include:
- Hemorrhage
- Kidney dialysis
- Liver disease
- Malabsorption e.g. celiac disease
- Pregnancy and lactation
- Alcohol consumption
Medication induced Folate Deficiency:
Medications can interfere with folate utilization, including:
- Anticonvulsant medications e.g phenytoin
- Metformin
- Methotrexate, an anti-cancer drug also used as an anti-inflammatory
- Sulfasalazine, used in Inflammatory bowel syndrome
- Birth control pills
Genetic or Metabolic disorder:
- Defects in folate metabolism
- Defects in folate absorption
Dietary Deficiency:
- A diet low in fresh fruits, vegetables, and fortified cereals