Epithelial ovarian tumors classification: Difference between revisions
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! colspan="6" style="background:#4479BA; color: #FFFFFF;" align="center" +|Ovarian epithelial tumors | ! colspan="6" style="background:#4479BA; color: #FFFFFF;" align="center" + |Ovarian epithelial tumors | ||
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!style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Serous tumors''' | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Serous tumors''' | ||
!style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Mucinous tumors''' | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Mucinous tumors''' | ||
!style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Endometrioid tumors''' | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Endometrioid tumors''' | ||
!style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Clear cell tumors''' | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Clear cell tumors''' | ||
!style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Transitional cell tumors''' | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Transitional cell tumors''' | ||
!style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Epithelial-stromal''' | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |'''Epithelial-stromal''' | ||
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! style="background:#4479BA; color: #FFFFFF;" align="center" + |Sex-cord stromal | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |Sex-cord stromal | ||
! style="background:#4479BA; color: #FFFFFF;" align="center" + |Germ cell | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |Germ cell | ||
! style="background:#4479BA; color: #FFFFFF;" align="center" + | | ! style="background:#4479BA; color: #FFFFFF;" align="center" + |Others | ||
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* '''Mixed germ cell tumors tumors''' | * '''Mixed germ cell tumors tumors''' | ||
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* Gonadoblastoma | |||
* Germ cell sex cord-stromal tumor of nongonadoblastoma type | |||
* Tumors of rete ovarii | |||
* Mesothelial tumors | |||
* Tumors of uncertain origin and miscellaneous tumors | |||
* Gestational trophoblastic diseases | |||
* Soft tissue tumors not specific to ovary | |||
* Malignant lymphomas leukemias, and plasmacytomas | |||
* Unclassified tumors | |||
* Secondary (metastatic) tumors | |||
* Tumor-like lesions | |||
|} | |} | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 18:56, 13 February 2019
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Epithelial ovarian tumors Microchapters |
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Differentiating Epithelial Ovarian Tumors from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Epithelial ovarian tumors classification On the Web |
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American Roentgen Ray Society Images of Epithelial ovarian tumors classification |
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Risk calculators and risk factors for Epithelial ovarian tumors classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Hannan Javed, M.D.[2]
Overview
Classification
General Classification
- Epithelial ovarian tumors can broadly be classified on the bases of histopathology and clinical behavior as:[1][2][3][4]
- Benign
- Borderline
- Malignant tumors
- Table below provides a summary of this classification:
| Epithelial ovarian tumors | ||
|---|---|---|
| Benign | Borderline | Malignant |
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WHO Classification of Ovarian Epithelial Tumors
- WHO classifies epithelial ovarian tumors on the basis of histology as follows:
- Serous tumors:
- Benign (cystadenoma)
- Borderline tumors (serous borderline tumor)
- Malignant (serous adenocarcinoma)
- Mucinous tumors:
- Benign (cystadenoma)
- Borderline tumors (mucinous borderline tumor)
- Malignant (mucinous adenocarcinoma)
- Endometrioid tumors:
- Benign (cystadenoma)
- Borderline tumors (endometrioid borderline tumor)
- Malignant (endometrioid adenocarcinoma)
- Clear cell tumors:
- Benign
- Borderline tumors
- Malignant (clear cell adenocarcinoma)
- Transitional cell tumors:
- Brenner tumor
- Brenner tumor of borderline malignancy
- Malignant Brenner tumor
- Transitional cell carcinoma (non-Brenner type)
- Epithelial-stromal:
- Adenosarcoma
- Carcinosarcoma (formerly mixed Müllerian tumors)
- Serous tumors:
| Ovarian epithelial tumors | |||||
|---|---|---|---|---|---|
| Serous tumors | Mucinous tumors | Endometrioid tumors | Clear cell tumors | Transitional cell tumors | Epithelial-stromal |
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Epithelial Ovarian Cancer Classification Based on Clinicopathologic and Molecular Evidence
- Recent advances in histopathology and a better understanding of clinicopathologic characteristics have led to a classification system that correlates histology and clinical characteristics;
- This classification subdivides malignant ovarian tumors in two types.
- Type I tumors generally arise from endometriosis or fallopian tubal related serous epithelium. They exhibit less aggressive clinical course and a different genetic profile relative to Type II.
- Type II tumors generally arise from fallopian tubal epithelium. They exhibit more aggressive clinical course and a different genetic profile relative to Type I.
| Epithelial Ovarian Cancer | |
|---|---|
| Type I | Type II |
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WHO Classification of Ovarian Tumors
| Ovarian Cancer | |||
|---|---|---|---|
| Epithelial | Sex-cord stromal | Germ cell | Others |
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References
- ↑ Rojas V, Hirshfield KM, Ganesan S, Rodriguez-Rodriguez L (December 2016). "Molecular Characterization of Epithelial Ovarian Cancer: Implications for Diagnosis and Treatment". Int J Mol Sci. 17 (12). doi:10.3390/ijms17122113. PMC 5187913. PMID 27983698.
- ↑ Horta M, Cunha TM (2015). "Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists". Diagn Interv Radiol. 21 (4): 277–86. doi:10.5152/dir.2015.34414. PMC 4498422. PMID 26054417.
- ↑ McCluggage WG (August 2011). "Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis". Pathology. 43 (5): 420–32. doi:10.1097/PAT.0b013e328348a6e7. PMID 21716157.
- ↑ Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J (April 2016). "The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications". Arch. Gynecol. Obstet. 293 (4): 695–700. doi:10.1007/s00404-016-4035-8. PMID 26894303.