Paget's disease of the breast history and symptoms: Difference between revisions
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==History and symptoms== | ==History and symptoms== | ||
Symptoms of Paget's disease of the breast usually occur in one breast. Some patients have two or more symptoms at presentation, | A detailed history documenting the length of time the lesion along with any associated symptoms should be taken. | ||
*[[ | Symptoms of Paget's disease of the breast usually occur in one breast but can present bilaterally<ref name="pmid16174159">{{cite journal |vauthors=Franceschini G, Masetti R, D'Ugo D, Palumbo F, D'Alba P, Mulè A, Costantini M, Belli P, Picciocchi A |title=Synchronous bilateral Paget's disease of the nipple associated with bilateral breast carcinoma |journal=Breast J |volume=11 |issue=5 |pages=355–6 |date=2005 |pmid=16174159 |doi=10.1111/j.1075-122X.2005.21722.x |url=}}</ref>. Some patients have two or more or a combination of the below symptoms at presentation, they can also be asymptomatic.<ref name="GaspariRicci2013">{{cite journal|last1=Gaspari|first1=Eleonora|last2=Ricci|first2=Aurora|last3=Liberto|first3=Valeria|last4=Scarano|first4=Angela Lia|last5=Fornari|first5=Maria|last6=Simonetti|first6=Giovanni|title=An Unusual Case of Mammary Paget’s Disease Diagnosed Using Dynamic Contrast-Enhanced MRI|journal=Case Reports in Radiology|volume=2013|year=2013|pages=1–5|issn=2090-6862|doi=10.1155/2013/206235}}</ref> Symptoms of Paget's disease of the breast include:<ref name=NIH>Paget's disease of the breast. National cancer institute. http://www.cancer.gov/types/breast/paget-breast-fact-sheet</ref><ref name="pmid4318756">{{cite journal |vauthors=Ashikari R, Park K, Huvos AG, Urban JA |title=Paget's disease of the breast |journal=Cancer |volume=26 |issue=3 |pages=680–5 |date=September 1970 |pmid=4318756 |doi= |url=}}</ref> | ||
*[[Puritis]], tingling, or redness in the nipple and/or areola | |||
*Flaking, crusty, or thickened [[skin]] on or around the nipple | *Flaking, crusty, or thickened [[skin]] on or around the nipple | ||
*[[Erosion]] or [[ulceration]] of the nipple | *[[Erosion]] or [[ulceration]] of the nipple | ||
*A flattened or inverted nipple | *A flattened or inverted nipple | ||
*[[Discharge]] from the nipple that may be yellowish or bloody | *[[Discharge]] from the nipple that may be yellowish or bloody | ||
*A palpable breast mass is present in 50% of patients. | |||
*Underlying [[breast cancer]] is present in 85%- 88% of cases. | |||
==References== | ==References== | ||
Revision as of 20:11, 17 February 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Symptoms of Paget's disease of the breast include itching, redness, thickened skin, and ulceration of the nipple.
History and symptoms
A detailed history documenting the length of time the lesion along with any associated symptoms should be taken. Symptoms of Paget's disease of the breast usually occur in one breast but can present bilaterally[1]. Some patients have two or more or a combination of the below symptoms at presentation, they can also be asymptomatic.[2] Symptoms of Paget's disease of the breast include:[3][4]
- Puritis, tingling, or redness in the nipple and/or areola
- Flaking, crusty, or thickened skin on or around the nipple
- Erosion or ulceration of the nipple
- A flattened or inverted nipple
- Discharge from the nipple that may be yellowish or bloody
- A palpable breast mass is present in 50% of patients.
- Underlying breast cancer is present in 85%- 88% of cases.
References
- ↑ Franceschini G, Masetti R, D'Ugo D, Palumbo F, D'Alba P, Mulè A, Costantini M, Belli P, Picciocchi A (2005). "Synchronous bilateral Paget's disease of the nipple associated with bilateral breast carcinoma". Breast J. 11 (5): 355–6. doi:10.1111/j.1075-122X.2005.21722.x. PMID 16174159.
- ↑ Gaspari, Eleonora; Ricci, Aurora; Liberto, Valeria; Scarano, Angela Lia; Fornari, Maria; Simonetti, Giovanni (2013). "An Unusual Case of Mammary Paget's Disease Diagnosed Using Dynamic Contrast-Enhanced MRI". Case Reports in Radiology. 2013: 1–5. doi:10.1155/2013/206235. ISSN 2090-6862.
- ↑ Paget's disease of the breast. National cancer institute. http://www.cancer.gov/types/breast/paget-breast-fact-sheet
- ↑ Ashikari R, Park K, Huvos AG, Urban JA (September 1970). "Paget's disease of the breast". Cancer. 26 (3): 680–5. PMID 4318756.