Glioblastoma multiforme classification: Difference between revisions
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==Overview== | ==Overview== |
Revision as of 18:03, 19 February 2019
Glioblastoma multiforme Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Marjan Khan M.B.B.S.[2]
Overview
Glioblastoma multiforme may be classified into several subtypes based on the origin (primary and secondary) and molecular alterations (classic, proneural, mesenchymal, and neural).[1][2]
Classification
Based on the origin
Glioblastoma multiforme may be classified according to the origin into two subtypes: Primary and secondary.[1]
Subtype of Glioblastoma multiforme | Characteristic features |
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Based on the molecular alterations
Glioblastoma multiforme may be classified according to the molecular alterations into four subtypes:[2]
- Classic
- Proneural
- Mesenchymal
- Neural
References
- ↑ 1.0 1.1 Classification of Glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/Glioblastoma
- ↑ 2.0 2.1 Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD; et al. (2010). "Integrated genomic analysis identifies clinically relevant subtypes of Glioblastoma multiforme characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1". Cancer Cell. 17 (1): 98–110. doi:10.1016/j.ccr.2009.12.020. PMC 2818769. PMID 20129251.