Leiomyosarcoma surgery: Difference between revisions
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==Overview== | ==Overview== | ||
Patients with [[leiomyosarcoma]] have many treatment options but surgery is considered the mainstay of treatment for all soft tissue sarcomas. The selection depends on the stage of the tumor. The options are surgery, radiation therapy, chemotherapy, or a combination of these methods. | Patients with [[leiomyosarcoma]] have many treatment options but surgery is considered the mainstay of treatment for all soft tissue sarcomas. The selection depends on the stage of the tumor. The options are surgery, radiation therapy, chemotherapy, or a combination of these methods. Treatment options are not chosen by the histological subtype of sarcoma but by tumor grade, size, and location of primary or metastatic disease. | ||
==Surgery== | ==Surgery== | ||
Revision as of 14:41, 5 March 2019
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Leiomyosarcoma Microchapters |
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Treatment |
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Case Studies |
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Leiomyosarcoma surgery On the Web |
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American Roentgen Ray Society Images of Leiomyosarcoma surgery |
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Risk calculators and risk factors for Leiomyosarcoma surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]
Overview
Patients with leiomyosarcoma have many treatment options but surgery is considered the mainstay of treatment for all soft tissue sarcomas. The selection depends on the stage of the tumor. The options are surgery, radiation therapy, chemotherapy, or a combination of these methods. Treatment options are not chosen by the histological subtype of sarcoma but by tumor grade, size, and location of primary or metastatic disease.
Surgery
- Surgery has been the main effective way of treating the leiomyosarcoma,regardless of the location of the tumor in the body.
- The goal of surgery is to remove the tumor and some surrounding tissue to cure leiomyosarcoma and to prevent the local recurrence.[1]
- Lymphadenectomy is generally not required as the tumor usually metastasize hematogenously and rarely through the lymph nodes.[2][3]
| Established Dx with CT/US and core biopsy reviewed by expert pathologist | |||||||||||||||||||||||||||||||||||||
| Established stage MRI of extremity and CXR/CT Chest | |||||||||||||||||||||||||||||||||||||
| Stage 1 low grade tumors | Stage 2 less than 5 cm high grade tumor | Stage 3 more than 5 cm high grade tumor or nodal disease | Stage 4 distant metastasis | ||||||||||||||||||||||||||||||||||
| Surgical resection | surgical resection with or without radiation | surgical resection with radiation with or without chemotherapy | chemotherapy with or without surgical resection | ||||||||||||||||||||||||||||||||||
References
- ↑ Nassar OA, Abdul Moaty SB, Khalil el-SA, El-Taher MM, El Najjar M (2010) Outcome and prognostic factors of uterine sarcoma in 59 patients: single institutional results. J Egypt Natl Canc Inst 22 (2):113-22. PMID: 21860468
- ↑ Park JY, Kim DY, Suh DS, Kim JH, Kim YM, Kim YT et al. (2008) Prognostic factors and treatment outcomes of patients with uterine sarcoma: analysis of 127 patients at a single institution, 1989-2007. J Cancer Res Clin Oncol 134 (12):1277-87. DOI:10.1007/s00432-008-0422-2 PMID: 18506484
- ↑ Leitao MM, Sonoda Y, Brennan MF, Barakat RR, Chi DS (2003) Incidence of lymph node and ovarian metastases in leiomyosarcoma of the uterus. Gynecol Oncol 91 (1):209-12. PMID: 14529683