Melanocytic nevus pathophysiology: Difference between revisions
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===Congenital melanocytic nevi (CMN)=== | ===Congenital melanocytic nevi (CMN)=== | ||
Congenital melanocytic nevi (CMN) are hamartomas lesions. During embryogenesis clonal proliferations of benign melanocytes may give rise to melanocytic nevi. | Congenital melanocytic nevi (CMN) are hamartomas lesions. During embryogenesis clonal proliferations of benign melanocytes may give rise to melanocytic nevi.<ref name="pmid15692463">{{cite journal |vauthors=Tannous ZS, Mihm MC, Sober AJ, Duncan LM |title=Congenital melanocytic nevi: clinical and histopathologic features, risk of melanoma, and clinical management |journal=J. Am. Acad. Dermatol. |volume=52 |issue=2 |pages=197–203 |date=February 2005 |pmid=15692463 |doi=10.1016/j.jaad.2004.07.020 |url=}}</ref><ref name="pmid20541682">{{cite journal |vauthors=Price HN, Schaffer JV |title=Congenital melanocytic nevi-when to worry and how to treat: Facts and controversies |journal=Clin. Dermatol. |volume=28 |issue=3 |pages=293–302 |date=2010 |pmid=20541682 |doi=10.1016/j.clindermatol.2010.04.004 |url=}}</ref> | ||
===Gross Pathology=== | ===Gross Pathology=== | ||
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Editors-In-Chief: Martin I. Newman, M.D., FACS, Cleveland Clinic Florida, [1];Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2] Michel C. Samson, M.D., FRCSC, FACS [3]
Overview
Melanocytic nevus is a benign growth on the skin (usually tan, brown, or flesh-colored) that contains a cluster of melanocytes and surrounding supportive tissue.
Pathophysiology
Congenital melanocytic nevi (CMN)
Congenital melanocytic nevi (CMN) are hamartomas lesions. During embryogenesis clonal proliferations of benign melanocytes may give rise to melanocytic nevi.[1][2]
Gross Pathology
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References
- ↑ Tannous ZS, Mihm MC, Sober AJ, Duncan LM (February 2005). "Congenital melanocytic nevi: clinical and histopathologic features, risk of melanoma, and clinical management". J. Am. Acad. Dermatol. 52 (2): 197–203. doi:10.1016/j.jaad.2004.07.020. PMID 15692463.
- ↑ Price HN, Schaffer JV (2010). "Congenital melanocytic nevi-when to worry and how to treat: Facts and controversies". Clin. Dermatol. 28 (3): 293–302. doi:10.1016/j.clindermatol.2010.04.004. PMID 20541682.