Dysplastic nevus risk factors: Difference between revisions
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==Risk Factors== | ==Risk Factors== | ||
Common risk factors for the development of dysplastic nevi are: | Common risk factors for the development of dysplastic nevi are:<ref name="pmid28077359">{{cite journal |vauthors=Ghiasvand R, Rueegg CS, Weiderpass E, Green AC, Lund E, Veierød MB |title=Indoor Tanning and Melanoma Risk: Long-Term Evidence From a Prospective Population-Based Cohort Study |journal=Am. J. Epidemiol. |volume=185 |issue=3 |pages=147–156 |date=February 2017 |pmid=28077359 |doi=10.1093/aje/kww148 |url=}}</ref><ref name="pmid18348450">{{cite journal |vauthors=Leiter U, Garbe C |title=Epidemiology of melanoma and nonmelanoma skin cancer--the role of sunlight |journal=Adv. Exp. Med. Biol. |volume=624 |issue= |pages=89–103 |date=2008 |pmid=18348450 |doi=10.1007/978-0-387-77574-6_8 |url=}}</ref><ref name="pmid30548854">{{cite journal |vauthors=Matas-Nadal C, Malvehy J, Ferreres JR, Boada A, Bodet D, Segura S, Salleras M, Azon A, Bel-Pla S, Bigata X, Campoy A, Curcó N, Dalmau J, Formigon M, Gonzalez A, Just M, Llistosella E, Nogues ME, Pedragosa R, Pujol JA, Sabat M, Smandia JA, Zaballos P, Puig S, Martí RM |title=Increasing incidence of lentigo maligna and lentigo maligna melanoma in Catalonia |journal=Int. J. Dermatol. |volume= |issue= |pages= |date=December 2018 |pmid=30548854 |doi=10.1111/ijd.14334 |url=}}</ref><ref name="pmid10630172">{{cite journal |vauthors=Greene MH |title=The genetics of hereditary melanoma and nevi. 1998 update |journal=Cancer |volume=86 |issue=11 Suppl |pages=2464–77 |date=December 1999 |pmid=10630172 |doi= |url=}}</ref><ref name="pmid30060076">{{cite journal |vauthors=Gu F, Chen TH, Pfeiffer RM, Fargnoli MC, Calista D, Ghiorzo P, Peris K, Puig S, Menin C, De Nicolo A, Rodolfo M, Pellegrini C, Pastorino L, Evangelou E, Zhang T, Hua X, DellaValle CT, Timothy Bishop D, MacGregor S, Iles MI, Law MH, Cust A, Brown KM, Stratigos AJ, Nagore E, Chanock S, Shi J, Consortium MM, Consortium M, Landi MT |title=Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma |journal=Hum. Mol. Genet. |volume=27 |issue=23 |pages=4145–4156 |date=December 2018 |pmid=30060076 |doi=10.1093/hmg/ddy282 |url=}}</ref><ref name="pmid30566178">{{cite journal |vauthors=Müller C, Wendt J, Rauscher S, Sunder-Plassmann R, Richtig E, Fae I, Fischer G, Okamoto I |title=Risk Factors of Subsequent Primary Melanomas in Austria |journal=JAMA Dermatol |volume= |issue= |pages= |date=December 2018 |pmid=30566178 |doi=10.1001/jamadermatol.2018.4645 |url=}}</ref> | ||
*Having more than 50 common moles | *Having more than 50 common moles | ||
*Sunlight: Sunlight is a source of UV radiation, which causes skin damage that can lead to melanoma and other skin cancers.Severe, blistering sunburns: People who have had at least one severe, blistering sunburn have an increased chance of melanoma. Although people who burn easily are more likely to have had sunburns as a child, sunburns during adulthood also increase the chance of melanoma. | *Sunlight: Sunlight is a source of UV radiation, which causes skin damage that can lead to melanoma and other skin cancers.Severe, blistering sunburns: People who have had at least one severe, blistering sunburn have an increased chance of melanoma. Although people who burn easily are more likely to have had sunburns as a child, sunburns during adulthood also increase the chance of melanoma. | ||
Revision as of 05:09, 4 June 2019
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Dysplastic nevus Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Dysplastic nevus risk factors On the Web |
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American Roentgen Ray Society Images of Dysplastic nevus risk factors |
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Risk calculators and risk factors for Dysplastic nevus risk factors |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Sunlight exposure is the most important risk factor for the development of dysplastic nevus.
Risk Factors
Common risk factors for the development of dysplastic nevi are:[1][2][3][4][5][6]
- Having more than 50 common moles
- Sunlight: Sunlight is a source of UV radiation, which causes skin damage that can lead to melanoma and other skin cancers.Severe, blistering sunburns: People who have had at least one severe, blistering sunburn have an increased chance of melanoma. Although people who burn easily are more likely to have had sunburns as a child, sunburns during adulthood also increase the chance of melanoma.
- Lifetime sun exposure: The greater the total amount of sun exposure over a lifetime, the greater the chance of melanoma.
- Tanning: Although having skin that tans well lowers the risk of sunburn, even people who tan well without sunburning increase their chance of melanoma by spending time in the sun without protection.
- Sunlight can be reflected by sand, water, snow, ice, and pavement. The sun's rays can get through clouds, windshields, windows, and light clothing. In the United States, skin cancer is more common where the sun exposure is more. For example, a larger proportion of people in Texas than Minnesota get skin cancer. Also, the sun exposure is more at higher elevations, such as in the mountains.
- Sunlamps and tanning booths: UV radiation from artificial sources, such as sunlamps and tanning booths, can cause skin damage and melanoma. Health care providers strongly encourage people, especially young people, to avoid using sunlamps and tanning booths. The risk of skin cancer is greatly increased by using sunlamps and tanning booths before age 30.
- Personal history: People who have had melanoma have an increased risk of developing other melanomas.
- Family history: Melanoma sometimes runs in families. People who have two or more close relatives (mother, father, sister, brother, or child) with melanoma have an increased chance of melanoma. In rare cases, members of a family will have an inherited disorder, such as xeroderma pigmentosum, that makes the skin extremely sensitive to the sun and greatly increases the chance of melanoma
- Skin that burns easily: People who have fair (pale) skin that burns easily in the sun, blue or gray eyes, red or blond hair, or many freckles have an increased chance of melanoma.
- Certain medical conditions or medicines: Medical conditions or medicines (such as some antibiotics, hormones, or antidepressants) that make skin more sensitive to the sun or that suppress the immune system increase the chance of melanoma.
|
Dysplastic nevus Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Dysplastic nevus risk factors On the Web |
|
American Roentgen Ray Society Images of Dysplastic nevus risk factors |
|
Risk calculators and risk factors for Dysplastic nevus risk factors |
References
- ↑ Ghiasvand R, Rueegg CS, Weiderpass E, Green AC, Lund E, Veierød MB (February 2017). "Indoor Tanning and Melanoma Risk: Long-Term Evidence From a Prospective Population-Based Cohort Study". Am. J. Epidemiol. 185 (3): 147–156. doi:10.1093/aje/kww148. PMID 28077359.
- ↑ Leiter U, Garbe C (2008). "Epidemiology of melanoma and nonmelanoma skin cancer--the role of sunlight". Adv. Exp. Med. Biol. 624: 89–103. doi:10.1007/978-0-387-77574-6_8. PMID 18348450.
- ↑ Matas-Nadal C, Malvehy J, Ferreres JR, Boada A, Bodet D, Segura S, Salleras M, Azon A, Bel-Pla S, Bigata X, Campoy A, Curcó N, Dalmau J, Formigon M, Gonzalez A, Just M, Llistosella E, Nogues ME, Pedragosa R, Pujol JA, Sabat M, Smandia JA, Zaballos P, Puig S, Martí RM (December 2018). "Increasing incidence of lentigo maligna and lentigo maligna melanoma in Catalonia". Int. J. Dermatol. doi:10.1111/ijd.14334. PMID 30548854.
- ↑ Greene MH (December 1999). "The genetics of hereditary melanoma and nevi. 1998 update". Cancer. 86 (11 Suppl): 2464–77. PMID 10630172.
- ↑ Gu F, Chen TH, Pfeiffer RM, Fargnoli MC, Calista D, Ghiorzo P, Peris K, Puig S, Menin C, De Nicolo A, Rodolfo M, Pellegrini C, Pastorino L, Evangelou E, Zhang T, Hua X, DellaValle CT, Timothy Bishop D, MacGregor S, Iles MI, Law MH, Cust A, Brown KM, Stratigos AJ, Nagore E, Chanock S, Shi J, Consortium MM, Consortium M, Landi MT (December 2018). "Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma". Hum. Mol. Genet. 27 (23): 4145–4156. doi:10.1093/hmg/ddy282. PMID 30060076.
- ↑ Müller C, Wendt J, Rauscher S, Sunder-Plassmann R, Richtig E, Fae I, Fischer G, Okamoto I (December 2018). "Risk Factors of Subsequent Primary Melanomas in Austria". JAMA Dermatol. doi:10.1001/jamadermatol.2018.4645. PMID 30566178.