Radiation proctitis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:

Overview

The laboratory findings in a patient with radiation proctitis include anemia, elevated white blood cell, deranged LFTs and electrolyte abnormalities

Laboratory Findings

There are no diagnostic laboratory findings associated with [disease name].

OR

An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].

OR

[Test] is usually normal among patients with [disease name].

OR

Laboratory findings consistent with the diagnosis of [disease name] include:

• [Abnormal test 1]
• [Abnormal test 2]
• [Abnormal test 3]

OR

Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].

The initial diagnostic workup for radiation proctitis includes the following:

• A complete blood count shows
  • Anemia, in case of chronic injury and rectal bleeding
• ESR
• Serum albumin
• Electrolyte studies and renal function tests are done, as chronic diarrhea may be associated with
  • Hypokalemia
  • Hypomagnesemia
  • Pre-renal failure
• Liver function tests
• Stool culture, to rule out parasites and infectious causes.
• Stool C. difficile toxin
• C-reactive protein can be measured, with an elevated level being an indication of inflammation.
• sexually transmitted infections testing, particularly in homosexual male or patients with severe rectal symptoms including urgency and tenesmus.