Kaposi's sarcoma classification: Difference between revisions
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| rowspan="1;" style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" |Classic Kaposi's sarcoma <ref name="pmid25889316">{{cite journal| author=Vincenzi B, D'Onofrio L, Frezza AM, Grasso RF, Fausti V, Santini D et al.| title=Classic Kaposi Sarcoma: to treat or not to treat? | journal=BMC Res Notes | year= 2015 | volume= 8 | issue= | pages= 138 | pmid=25889316 | doi=10.1186/s13104-015-1076-1 | pmc=4395989 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25889316 }}</ref> | | rowspan="1;" style="padding: 5px 5px; background: #DCDCDC; font-weight: bold;" |Classic Kaposi's sarcoma <ref name="pmid25889316">{{cite journal| author=Vincenzi B, D'Onofrio L, Frezza AM, Grasso RF, Fausti V, Santini D et al.| title=Classic Kaposi Sarcoma: to treat or not to treat? | journal=BMC Res Notes | year= 2015 | volume= 8 | issue= | pages= 138 | pmid=25889316 | doi=10.1186/s13104-015-1076-1 | pmc=4395989 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25889316 }}</ref> | ||
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* | * Vascular sarcoma | ||
* | * Common in Mediterranean elderly men | ||
* | *Indolent clinical behavior | ||
* | *Pigmented macular–papular lesions on mucocutaneous surface | ||
* | *Typically appears as dark blue or purple | ||
*Lesions may present as solitary nodules or plaques and tumors to a size of several centimeters | *Lesions may present as solitary nodules or plaques and tumors to a size of several centimeters | ||
* | *Usually, present in the skin of the lower extremities and progresses very slowly | ||
*Mucous membranes of the mouth and GI tract and regional lymph nodes | *Mucous membranes of the mouth and GI tract and regional lymph nodes could be affected | ||
*Factors that affect the selection of local therapy are the extent and location of the lesions and the rapidity of clinical change | *Factors that affect the selection of local therapy are the extent and location of the lesions and the rapidity of clinical change | ||
*Local therapy includes surgery, intra-lesional injection of vinblastine, topical retinoid, radiotherapy and cryotherapy. | *Local therapy includes surgery, intra-lesional injection of vinblastine, topical retinoid, radiotherapy and cryotherapy. | ||
* | *Radiotherapy is a treatment option for the multifocal but relatively localized KS. <br /> | ||
* | * | ||
* | * | ||
Revision as of 21:30, 14 October 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2] Huda A. Karman, M.D.
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Kaposi's sarcoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Kaposi's sarcoma classification On the Web |
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American Roentgen Ray Society Images of Kaposi's sarcoma classification |
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Risk calculators and risk factors for Kaposi's sarcoma classification |
Overview
Kaposi's sarcoma may be classified according to the clinical setting of the disease into five subtypes include Classic Kaposi's sarcoma, African cutaneous Kaposi's sarcoma, African lymphadenopathic Kaposi's sarcoma, Immunosuppression-associated Kaposi's sarcoma, and AIDS-associated Kaposi's sarcoma.
Classification
- According to the clinical setting of the disease, clinical presentation, epidemiology, and prognosis Kaposi's sarcoma may be classified into five different subtypes which include:[1][2][3]
- Classic Kaposi's sarcoma
- African cutaneous Kaposi's sarcoma
- African lymphadenopathic Kaposi's sarcoma
- Iatrogenic Kaposi's sarcoma (immunosuppression-associated Kaposi's sarcoma)
- AIDS-associated Kaposi's sarcoma
- African cutaneous Kaposi's sarcoma and African lymphadenopathic Kaposi's sarcoma could be classified under the term of endemic Kaposi's sarcomas.
| Types | Characteristics |
|---|---|
| Classic Kaposi's sarcoma [4] |
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| African cutaneous Kaposi's sarcoma |
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| African lymphadenopathic Kaposi's sarcoma |
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| Iatrogenic Kaposi's sarcoma (immunosuppression-associated Kaposi's sarcoma) |
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| AIDS-associated Kaposi's sarcoma |
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References
- ↑ Uldrick TS, Whitby D (June 2011). "Update on KSHV epidemiology, Kaposi Sarcoma pathogenesis, and treatment of Kaposi Sarcoma". Cancer Lett. 305 (2): 150–62. doi:10.1016/j.canlet.2011.02.006. PMID 21377267.
- ↑ Krigel RL, Laubenstein LJ, Muggia FM (June 1983). "Kaposi's sarcoma: a new staging classification". Cancer Treat Rep. 67 (6): 531–4. PMID 6861160.
- ↑ Grayson W, Pantanowitz L (July 2008). "Histological variants of cutaneous Kaposi sarcoma". Diagn Pathol. 3: 31. doi:10.1186/1746-1596-3-31. PMC 2526984. PMID 18655700.
- ↑ Vincenzi B, D'Onofrio L, Frezza AM, Grasso RF, Fausti V, Santini D; et al. (2015). "Classic Kaposi Sarcoma: to treat or not to treat?". BMC Res Notes. 8: 138. doi:10.1186/s13104-015-1076-1. PMC 4395989. PMID 25889316.