Scrotal mass pathophysiology: Difference between revisions
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===Physiology=== | ===Physiology=== | ||
Scrotal is extention of abdominal wall contains testis , tunica vaginalis ,spermatic cord,epididimysis and appendix testis.Testis has seminiferous tubules that has germ cells,sertoli cells, and leydig cells .Germ cells develop into spermatogenesis and produce gametes.Sertoli secrete inhibin and leydig cell produce testostrone.<ref name="pmid24598113">{{cite journal| author=Djureinovic D, Fagerberg L, Hallström B, Danielsson A, Lindskog C, Uhlén M et al.| title=The human testis-specific proteome defined by transcriptomics and antibody-based profiling. | journal=Mol Hum Reprod | year= 2014 | volume= 20 | issue= 6 | pages= 476-88 | pmid=24598113 | doi=10.1093/molehr/gau018 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24598113 }} </ref>The normal physiology of germ cells is production of gametes which are reproductive cells.After migration of these cells to gonads, they udergo meiosis to produce gametes.<ref name="pmid18295574">{{cite journal| author=Cinalli RM, Rangan P, Lehmann R| title=Germ cells are forever. | journal=Cell | year= 2008 | volume= 132 | issue= 4 | pages= 559-62 | pmid=18295574 | doi=10.1016/j.cell.2008.02.003 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18295574 }} </ref> | [[Scrotal swelling|Scrotal]] is extention of [[abdominal wall]] contains [[Testis cords|testis]] , [[tunica vaginalis]] ,[[spermatic cord]],[[Ewald sphere|epididimysis]] and [[appendix testis]].Testis has [[Seminiferous epithelium|seminiferous]] [[Tubule|tubules]] that has [[germ cells]],[[Sertoli cell|sertoli cells]], and [[leydig cells]] .[[Germ cells]] develop into [[spermatogenesis]] and produce [[gametes]].[[Sertoli-Leydig cell tumour|Sertoli]] secrete [[inhibin]] and [[leydig cell]] produce [[Testosterone (injection)|testostrone.]]<ref name="pmid24598113">{{cite journal| author=Djureinovic D, Fagerberg L, Hallström B, Danielsson A, Lindskog C, Uhlén M et al.| title=The human testis-specific proteome defined by transcriptomics and antibody-based profiling. | journal=Mol Hum Reprod | year= 2014 | volume= 20 | issue= 6 | pages= 476-88 | pmid=24598113 | doi=10.1093/molehr/gau018 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24598113 }} </ref>The normal [[physiology]] of [[Germ cell|germ cells]] is production of [[Gamete|gametes]] which are [[Reproductive cloning|reproductive cells]].After migration of these cells to [[gonads]], they udergo [[meiosis]] to produce [[Gamete|gametes]].<ref name="pmid18295574">{{cite journal| author=Cinalli RM, Rangan P, Lehmann R| title=Germ cells are forever. | journal=Cell | year= 2008 | volume= 132 | issue= 4 | pages= 559-62 | pmid=18295574 | doi=10.1016/j.cell.2008.02.003 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18295574 }} </ref> | ||
===Phatogenesis=== | ===Phatogenesis=== | ||
Revision as of 15:51, 31 October 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Niloofarsadaat Eshaghhosseiny, MD[2]
Overview
Deponds on the causes phatophysiology is different.Inadequate fixation of the lower pole of the testis to the tunica vaginalis causes testicular tortion . If fixation is absent , the testis may torse (twist) on the spermatic cord, lead to produceischemia from reduced arterial inflow and venous outflow obstruction . Testicular torsion etiology include (eg, trauma, vigorous physical activity) or spontaneously. Acquired hernias due loss of mechanical integrity of the abdominal wall muscles and tendons . primary hernia due Genetic or systemic extracellular matrix disorders and defective wound healing after laparotomy and hernia repairs may predispose to incisional hernias.
Pathophisiology
Physiology
Scrotal is extention of abdominal wall contains testis , tunica vaginalis ,spermatic cord,epididimysis and appendix testis.Testis has seminiferous tubules that has germ cells,sertoli cells, and leydig cells .Germ cells develop into spermatogenesis and produce gametes.Sertoli secrete inhibin and leydig cell produce testostrone.[1]The normal physiology of germ cells is production of gametes which are reproductive cells.After migration of these cells to gonads, they udergo meiosis to produce gametes.[2]
Phatogenesis
Genetics
Associated Conditions
Gros Pathology
Microscopic Pathology
Refrences
References
- ↑ Djureinovic D, Fagerberg L, Hallström B, Danielsson A, Lindskog C, Uhlén M; et al. (2014). "The human testis-specific proteome defined by transcriptomics and antibody-based profiling". Mol Hum Reprod. 20 (6): 476–88. doi:10.1093/molehr/gau018. PMID 24598113.
- ↑ Cinalli RM, Rangan P, Lehmann R (2008). "Germ cells are forever". Cell. 132 (4): 559–62. doi:10.1016/j.cell.2008.02.003. PMID 18295574.