Beriberi differential diagnosis: Difference between revisions
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==Overview== | ==Overview== | ||
Beriberi should be differentiated from other causes of cardiac dysfunction (wet beriberi), peripheral neuropathy (dry beriberi), delirium (WKS), and other disorders caused by excessive alcohol drinking. However, the differential diagnosis is broad due to the non-specific symptoms of cardiac and neural involvement associated with the condition. | |||
==Differentiating Beriberi from other | ==Differentiating Beriberi from other Diseases== | ||
Beriberi should be differentiated from other causes of cardiac dysfunction (wet beriberi), peripheral neuropathy (dry beriberi), delirium (WKS), and other disorders caused by excessive alcohol drinking. However, the differential diagnosis is broad due to the non-specific symptoms of cardiac and neural involvement associated with the condition. | Beriberi should be differentiated from other causes of cardiac dysfunction (wet beriberi), peripheral neuropathy (dry beriberi), delirium (WKS), and other disorders caused by excessive alcohol drinking. However, the differential diagnosis is broad due to the non-specific symptoms of cardiac and neural involvement associated with the condition. | ||
{| class="wikitable" | {| class="wikitable" | ||
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* Dyspnea/Orthopnea | * Dyspnea/Orthopnea | ||
* Edema | * Edema | ||
* [[Syncope]] | *[[Syncope]] | ||
* Palpitations | * Palpitations | ||
| | | | ||
* [[Hyponatremia]] | *[[Hyponatremia]] | ||
* Elevated [[brain natriuretic peptide]] | * Elevated [[brain natriuretic peptide]] | ||
* Elevated [[troponin]] (in ischemia) | * Elevated [[troponin]] (in ischemia) | ||
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|Delirium and delusional disorders | |Delirium and delusional disorders | ||
| | | | ||
* [[Acute liver failure]] | |||
* Acute metabolic and electrolyte disturbances | |||
* Infections/sepsis | |||
* Toxins/drug overdose | |||
| | | | ||
* Disturbed attention | |||
* Poor cognition | |||
* Impaired psychomotor activity | |||
* Emotional instability | |||
| | | | ||
* [[Arterial blood gas|Arterial blood gases]] | |||
* CBC: [[Leukocytosis|Leucocytosis]] | |||
* [[Blood culture]] | |||
* Glucose and electrolyte levels | |||
|- | |- | ||
|Nerve entrapment disorders | |Nerve entrapment disorders | ||
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|Within the distribution of the affected nerve, the patient may complain of: | |Within the distribution of the affected nerve, the patient may complain of: | ||
* [[Paresthesia|Parasthesia]] | *[[Paresthesia|Parasthesia]] | ||
* Sensory loss | * Sensory loss | ||
* Pain | * Pain | ||
* [[Muscle weakness]] | *[[Muscle weakness]] | ||
* [[Muscle atrophy]] | *[[Muscle atrophy]] | ||
* | * | ||
| Line 74: | Line 86: | ||
* Poor insulin compliance | * Poor insulin compliance | ||
* Infections/sepsis | * Infections/[[sepsis]] | ||
* Stress | * Stress | ||
* Idiopathic | * Idiopathic | ||
| | | | ||
* Early: [[Polydipsia]] and [[polyuria]] | * Early: [[Polydipsia]] and [[polyuria]] | ||
* [[Anorexia]] | *[[Anorexia]] | ||
* Nausea and vomiting | * Nausea and vomiting | ||
* Abdominal tenderness | * Abdominal tenderness | ||
* Late: Disturbed consciousness | * Late: Disturbed consciousness | ||
| | | | ||
* Hyperglycemia | *[[Hyperglycemia]] | ||
* Lower PH and bicarbonate levels | * Lower PH and bicarbonate levels | ||
* Ketonemia and ketonuria | * Ketonemia and [[ketonuria]] | ||
* Electrolyte disturbances | * Electrolyte disturbances | ||
* Impaired renal function | * Impaired renal function | ||
|- | |- | ||
|Hyperthyroidism | |Hyperthyroidism | ||
| | | | ||
* Primary: Grave's disease, toxic thyroid nodules and adenoma | * Primary: [[Graves' disease|Grave's disease]], toxic thyroid nodules and adenoma | ||
* Secondary: Pituitary | * Secondary: [[Pituitary adenoma]]<nowiki/>s and intracranial tumors | ||
* Tertiary:Intracranial tumors involving the hypothalamus | * Tertiary:Intracranial tumors involving the [[hypothalamus]] | ||
| | | | ||
* [[Goiter]] | *[[Goiter]] | ||
* [[Palpitations]] | *[[Palpitations]] | ||
* [[Anxiety]] | *[[Anxiety]] | ||
* Heat intolerance | * Heat intolerance | ||
* [[Insomnia]] | *[[Insomnia]] | ||
* [[Weight loss]] | *[[Weight loss]] | ||
* [[Diarrhea]] | *[[Diarrhea]] | ||
* [[Exophthalmos|Exophthalmus]] | *[[Exophthalmos|Exophthalmus]] | ||
| | | | ||
* Elevated T3 and T4 hormones | * Elevated T3 and T4 hormones | ||
* TSH: Reduced in 1ry and Elevated in 2ry hyperthyroidism. | *[[Thyroid-stimulating hormone|TSH]]: Reduced in 1ry and Elevated in 2ry hyperthyroidism. | ||
* Thyroid stimulating antibodies: Elevated only in Grave's disease | * Thyroid stimulating antibodies: Elevated only in Grave's disease | ||
|- | |- | ||
|Folic acid deficiency | |Folic acid deficiency | ||
| | | | ||
* [[Malnutrition]] | *[[Malnutrition]] | ||
* Intestinal bacterial overgrowth | * Intestinal bacterial overgrowth | ||
* [[Celiac disease|Celiac]] disease | *[[Celiac disease|Celiac]] disease | ||
* [[Blind loop syndrome]] | *[[Blind loop syndrome]] | ||
* [[Inflammatory bowel disease]] | *[[Inflammatory bowel disease]] | ||
* Pregnancy | * Pregnancy | ||
* Vegetarians | * Vegetarians | ||
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| | | | ||
* Low serum folate <2.5ng/ml | * Low serum folate <2.5ng/ml | ||
* CBC: Macrocytic anemia and low correlated reticulocyte count | * CBC: [[Macrocytic anemia]] and low correlated reticulocyte count | ||
* Peripheral blood smear: Neutrophil granulocytes and anisocytosis | * Peripheral blood smear: Neutrophil granulocytes and [[anisocytosis]] | ||
|} | |} | ||
Revision as of 20:34, 6 November 2019
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Beriberi Microchapters |
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Beriberi differential diagnosis On the Web |
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American Roentgen Ray Society Images of Beriberi differential diagnosis |
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Risk calculators and risk factors for Beriberi differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdelrahman Ibrahim Abushouk, MD[2]
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Overview
Beriberi should be differentiated from other causes of cardiac dysfunction (wet beriberi), peripheral neuropathy (dry beriberi), delirium (WKS), and other disorders caused by excessive alcohol drinking. However, the differential diagnosis is broad due to the non-specific symptoms of cardiac and neural involvement associated with the condition.
Differentiating Beriberi from other Diseases
Beriberi should be differentiated from other causes of cardiac dysfunction (wet beriberi), peripheral neuropathy (dry beriberi), delirium (WKS), and other disorders caused by excessive alcohol drinking. However, the differential diagnosis is broad due to the non-specific symptoms of cardiac and neural involvement associated with the condition.
| Disorders | Etiology | Clinical Presentation | Laboratory findings |
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| Cardiomyopathy due to other causes as alcohol or DM |
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| Delirium and delusional disorders |
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| Nerve entrapment disorders | Chronic injuries to nerves as they pass between bones and ligaments:
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Within the distribution of the affected nerve, the patient may complain of:
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| Alcoholic hepatitis |
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| Diabetic ketoacidosis | In patients with type 1 DM, exposed to:
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| Hyperthyroidism |
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| Folic acid deficiency |
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