Central pontine myelinolysis history and symptoms: Difference between revisions
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{{CMG}}; {{AE}} {{MMJ}} | {{CMG}}; {{AE}} {{MMJ}} | ||
==Overview== | ==Overview== | ||
<br /> | <br />spastic quadriparesis, dysarthria, pseudobulbar palsy, and altered mental status. In some patients, parkinsonian features, behavioral manifestations, and neuropsychological symptoms can also be present | ||
behavioral manifestations (personality changes, labile affect, disinhibition, poor judgment, paranoid delusions, emotional lability, delirium, hallucinations, and catatonia) | |||
==History and Symptoms== | ==History and Symptoms== | ||
===History=== | ===History=== | ||
Patients with [disease | Patients with central pontine myelinolysis may have a positive history of: | ||
*[ | *[[Malnutrition]] | ||
*[ | *[[Alcohol abuse|Alcohol use disorder]] | ||
*[ | *[[Chronic liver disease]] | ||
*[[Hyperemesis gravidarum]] | |||
These patients with central pontine myelinolysis most commonly have a history of rapid [[sodium]] correction, greater than 0.5-1.0 mEq/L per hour. | |||
The most susceptible patients are those with: | |||
*Chronic [[hyponatremia]] (>48 hours) | |||
*Severe [[hyponatremia]] (Na <120 mEq/L) | |||
*Both Chronic [[hyponatremia]] and severe [[hyponatremia]] | |||
===Common Symptoms=== | ===Common Symptoms=== |
Revision as of 00:15, 28 December 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
spastic quadriparesis, dysarthria, pseudobulbar palsy, and altered mental status. In some patients, parkinsonian features, behavioral manifestations, and neuropsychological symptoms can also be present
behavioral manifestations (personality changes, labile affect, disinhibition, poor judgment, paranoid delusions, emotional lability, delirium, hallucinations, and catatonia)
History and Symptoms
History
Patients with central pontine myelinolysis may have a positive history of:
These patients with central pontine myelinolysis most commonly have a history of rapid sodium correction, greater than 0.5-1.0 mEq/L per hour.
The most susceptible patients are those with:
- Chronic hyponatremia (>48 hours)
- Severe hyponatremia (Na <120 mEq/L)
- Both Chronic hyponatremia and severe hyponatremia
Common Symptoms
Common symptoms of [disease] include:
- [Symptom 1]
- [Symptom 2]
- [Symptom 3]
Less Common Symptoms
Less common symptoms of [disease name] include
- [Symptom 1]
- [Symptom 2]
- [Symptom 3]