Central pontine myelinolysis primary prevention: Difference between revisions
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To prevent central pontine myelinolysis in patients with [[hyponatremia]], the [[hyponatremia]] should be corrected at a rate not exceeding 10 mmol/L/24 h or 0.5 mEq/L/h; or 18 mEq/L/48hrs to minimize the risk of this condition developing from the overly rapid reversal of [[hyponatremia]], thus avoiding [[demyelination]].<ref name="pmid24569125">{{cite journal| author=Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D et al.| title=Clinical practice guideline on diagnosis and treatment of hyponatraemia. | journal=Eur J Endocrinol | year= 2014 | volume= 170 | issue= 3 | pages= G1-47 | pmid=24569125 | doi=10.1530/EJE-13-1020 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24569125 }} </ref> | |||
Effective measures for the primary prevention of | |||
Effective measures for the primary prevention of central pontine myelinolysis include: | |||
*[Measure1] | *[Measure1] | ||
*[Measure2] | *[Measure2] | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Primary Prevention
To prevent central pontine myelinolysis in patients with hyponatremia, the hyponatremia should be corrected at a rate not exceeding 10 mmol/L/24 h or 0.5 mEq/L/h; or 18 mEq/L/48hrs to minimize the risk of this condition developing from the overly rapid reversal of hyponatremia, thus avoiding demyelination.[1]
Effective measures for the primary prevention of central pontine myelinolysis include:
- [Measure1]
- [Measure2]
- [Measure3]
References
- ↑ Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D; et al. (2014). "Clinical practice guideline on diagnosis and treatment of hyponatraemia". Eur J Endocrinol. 170 (3): G1–47. doi:10.1530/EJE-13-1020. PMID 24569125.