Impaired wound healing

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2] Luke Rusowicz-Orazem, B.S.

Causes

Life Threatening Causes

• Adrenal Cancer 
• Adrenal incidentaloma 
• Adrenocortical carcinoma 
• Cancer
• Chronic renal failure
• Cirrhosis of liver
• Congestive cardiac failure
• Functioning pancreatic endocrine tumor 
• Pituitary cancer
• Pituitary tumors

Common Causes

• Alcohol
• Aluminum chloride
• Chemotherapeutics
• Chlorhexidine
• Chronic renal failure
• Chronic suppuration
• Diabetes mellitus
• Drugs- Cyclophosphamide
• Hepatitis
• Immunosuppresives
• Influenza
• Leukemia
• Peripheral vascular disease
• Protein depletion
• Topical antiseptics
• Topical petrolatum
• Topical hemostatic preparation
• Tumor cachexia
• Vitamin deficiency
• Weight loss
• Zinc deficiency

Causes by Organ System

Cardiovascular	Arterial occlusive disease, Chronic venous insufficiency, Congestive cardiac failure, Lymphedema, Peripheral vascular disease
Chemical/Poisoning	Alcohol, Aluminum chloride, Nicotine replacement therapy, Smoking, Topical petrolatum
Dental	No underlying causes
Dermatologic	Lymphedema
Drug Side Effect	Chemotherapy, Chlorhexidine, Cyclophosphamide, Immunosuppresives, Nicotine replacement therapy, Topical antiseptics
Ear Nose Throat	No underlying causes
Endocrine	Adrenal adenoma, Adrenal cancer , Adrenal cortex diseases, Adrenal gland hyperfunction , Adrenal incidentaloma , Adrenocortical carcinoma , Circulatory disorder , Complement component deficiency , Complement receptor deficiency , Functioning pancreatic endocrine tumor , Hyperadrenalism , Marasmus, Obesity, Pituitary cancer, Pituitary tumors, Weight loss
Environmental	No underlying causes
Gastroenterologic	Cirrhosis of liver, Marasmus
Genetic	Congenital disorder of glycosylation type x, Ehlers-danlos syndrome , Leukocyte adhesion defect , Mandibuloacral dysplasia
Hematologic	Diabetes mellitus, Factor xii deficiency , Factor xiii deficiency, Hypoalbuminemia, Hypoproteinemia, Lack of blood supply, Leukemia, Protein depletion, Sickle cell disease, Topical hemostatic preparation, Zinc deficiency
Iatrogenic	Chemotherapy, Radiation therapy, Topical antiseptics
Infectious Disease	Chronic suppuration, Fungal infection, Hepatitis, Hiv, Infection, Influenza
Musculoskeletal/Orthopedic	Spinal cord disease
Neurologic	Adrenal cortex diseases
Nutritional/Metabolic	Diabetes mellitus, Kwashiokar, Malnutrition, Obesity, Protein depletion, Vitamin deficiency, Weight loss, Zinc deficiency
Obstetric/Gynecologic	No underlying causes
Oncologic	Adrenal adenoma, Adrenal cancer , Adrenal incidentaloma , Adrenocortical carcinoma , Cancer, Functioning pancreatic endocrine tumor , Leukemia, Pituitary cancer, Pituitary tumors, Tumor cachexia
Ophthalmologic	No underlying causes
Overdose/Toxicity	Alcohol
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	Chronic renal failure
Rheumatology/Immunology/Allergy	No underlying causes
Sexual	Hiv
Trauma	Aging, Chronic ulcer, Cirrhosis of liver
Urologic	No underlying causes
Miscellaneous	No underlying causes

Cause in Alphabetical Order

• Adrenal Cancer 
• Adrenal Cortex Diseases
• Adrenal gland hyperfunction 
• Adrenal incidentaloma 
• Adrenocortical carcinoma 
• Aging
• Alcohol
• Aluminum chloride
• Arterial occlusive disease
• Cancer
• Chemotherapy
• Chlorhexidine
• Chronic renal failure
• Chronic suppuration
• Chronic ulcer
• Chronic venous insufficiency
• Circulatory disorder 
• Cirrhosis of liver
• Complement component deficiency 
• Complement receptor deficiency 
• Congenital disorder of glycosylation type X
• Congestive cardiac failure
• Cyclophosphamide
• Diabetes mellitus
• Ehlers-Danlos syndrome
• Factor XII Deficiency 
• Factor XIII Deficiency
• Functioning pancreatic endocrine tumor 
• Fungal infection
• Hepatitis
• HIV
• Hyperadrenalism 
• Hypoalbuminemia
• Hypoproteinemia
• Immunosuppresives
• Influenza
• Kwashiokar
• Lack of blood supply
• Leukemia
• Leukocyte Adhesion Defect 
• Lymphedema
• Malnutrition
• Mandibuloacral dysplasia 
• Marasmus
• Nicotine replacement therapy
• Obesity
• Peripheral artery disease
• Peripheral vascular disease
• Pituitary cancer
• Pituitary tumors
• Protein depletion
• Radiation therapy
• Sickle cell disease
• Smoking
• Spinal cord disease
• Topical antiseptics
• Topical hemostatic preparation
• Topical petrolatum
• Tumor cachexia
• Vitamin deficiency
• Weight loss
• Zinc deficiency

References

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