Transposition of the great vessels causes: Difference between revisions
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*The etiology for transposition of the great arteries is unknown and is presumed to be multifactorial.<ref name="Praagh2010">{{cite journal|last1=Praagh|first1=Richard Van|title=Normally and Abnormally Related Great Arteries|journal=World Journal for Pediatric and Congenital Heart Surgery|volume=1|issue=3|year=2010|pages=364–385|issn=2150-1351|doi=10.1177/2150135110380239}}</ref> | *The etiology for transposition of the great arteries is unknown and is presumed to be multifactorial.<ref name="Praagh2010">{{cite journal|last1=Praagh|first1=Richard Van|title=Normally and Abnormally Related Great Arteries|journal=World Journal for Pediatric and Congenital Heart Surgery|volume=1|issue=3|year=2010|pages=364–385|issn=2150-1351|doi=10.1177/2150135110380239}}</ref> | ||
*The embryology likely involves abnormal persistence of the subaortic conus with resorption or underdevelopment of the | *The embryology likely involves abnormal persistence of the subaortic conus with resorption or underdevelopment of the infundibulum. This abnormality aligns the [[aorta]] anterior and superior with the [[right ventricle]] during development. | ||
*Generally, TGA is not known to be associated with any specific single gene defect, but some studies have shown possible genetic association in some cases of TGA, involving deletions of chromosome 22q11. | *Generally, TGA is not known to be associated with any specific single gene defect, but some studies have shown possible genetic association in some cases of TGA, involving deletions of chromosome 22q11. | ||
Latest revision as of 17:01, 25 February 2020
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Transposition of the great vessels Microchapters |
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Classification |
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Differentiating Transposition of the great vessels from other Diseases |
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Diagnosis |
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Treatment |
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Surgery |
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Case Studies |
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Transposition of the great vessels causes On the Web |
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American Roentgen Ray Society Images of Transposition of the great vessels causes |
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Risk calculators and risk factors for Transposition of the great vessels causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4];Kristin Feeney, B.S. [5]
Overview
The causes for transposition of the great arteries is unknown and is presumed to be multifactorial. The embryology likely involves abnormal persistence of the subaortic conus with resorption or underdevelopment of the subpulmonary conus (infundibulum). This abnormality aligns the aorta anterior and superior with the right ventricle during development.
Causes
- The etiology for transposition of the great arteries is unknown and is presumed to be multifactorial.[1]
- The embryology likely involves abnormal persistence of the subaortic conus with resorption or underdevelopment of the infundibulum. This abnormality aligns the aorta anterior and superior with the right ventricle during development.
- Generally, TGA is not known to be associated with any specific single gene defect, but some studies have shown possible genetic association in some cases of TGA, involving deletions of chromosome 22q11.
References
- ↑ Praagh, Richard Van (2010). "Normally and Abnormally Related Great Arteries". World Journal for Pediatric and Congenital Heart Surgery. 1 (3): 364–385. doi:10.1177/2150135110380239. ISSN 2150-1351.