Endocardial cushion defect medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]

Overview

The management of endocardial cushion defect depends upon the type of defect, underlying etiology and associated cardiac conditions. Surgical correction of defective valve holds the the mainstay of treatment for endocardial cushion. Medical management provides supportive care in preparing the patient for surgery.

Medical Therapy

The management of endocardial cushion defect depends upon the type of defect, underlying etiology and associated cardiac conditions. Surgical correction of defective valve holds the the mainstay of treatment for endocardial cushion. The goal of medical management is to improve cardiac function as a prerequisite for surgery.

Medical management of endocardial cushion defect includes:

Medications	Mechanism of Action	Drugs
Diuretics	To reduce volume overload and pulmonary congestion	Loop (eg, furosemide) Thiazide diuretics
Inotropic agents	To improve myocardial contractility	Digoxin
ACE inhibitors	To reduce afterload Decreasing left-to-right shunting	Lisinopril

Nutritional Support

• Caloric supplementation is often needed in patients with poor feeding and failure to thrive.