Analgesic nephropathy diagnostic study of choice: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 12: | Line 12: | ||
* Renal biopsy is the diagnostic study of choice.<ref name="Keen Aeddula 2020 p. ">{{cite | last=Keen | first=MU | last2=Aeddula | first2=NR | title=Analgesic Nephropathy | chapter=article-17511 | publisher=StatPearls Publishing | publication-place=Treasure Island (FL) | year=2020 | pmid=31082145 | url=http://www.ncbi.nlm.nih.gov/books/NBK541101/ | access-date=2020-07-06 | page=}}</ref> | * Renal biopsy is the diagnostic study of choice.<ref name="Keen Aeddula 2020 p. ">{{cite | last=Keen | first=MU | last2=Aeddula | first2=NR | title=Analgesic Nephropathy | chapter=article-17511 | publisher=StatPearls Publishing | publication-place=Treasure Island (FL) | year=2020 | pmid=31082145 | url=http://www.ncbi.nlm.nih.gov/books/NBK541101/ | access-date=2020-07-06 | page=}}</ref> | ||
* However, renal biopsy is an invasive procedure and there is risk of complications, therefore CT scan without contrast of the abdomen is usually preferred.<ref name="Keen Aeddula 2020 p. ">{{cite | last=Keen | first=MU | last2=Aeddula | first2=NR | title=Analgesic Nephropathy | chapter=article-17511 | publisher=StatPearls Publishing | publication-place=Treasure Island (FL) | year=2020 | pmid=31082145 | url=http://www.ncbi.nlm.nih.gov/books/NBK541101/ | access-date=2020-07-06 | page=}}</ref><ref name="pmid9459649">{{cite journal |author=de Broe ME, Elseviers MM |title=Analgesic nephropathy |journal=N. Engl. J. Med. |volume=338 |issue=7 |pages=446–52 |year=1998 |month=February |pmid=9459649 |doi= |url=http://content.nejm.org/cgi/pmidlookup?view=short&pmid=9459649&promo=ONFLNS19}}</ref> | * However, renal biopsy is an invasive procedure and there is risk of complications, therefore CT scan without contrast of the abdomen is usually preferred.<ref name="Keen Aeddula 2020 p. ">{{cite | last=Keen | first=MU | last2=Aeddula | first2=NR | title=Analgesic Nephropathy | chapter=article-17511 | publisher=StatPearls Publishing | publication-place=Treasure Island (FL) | year=2020 | pmid=31082145 | url=http://www.ncbi.nlm.nih.gov/books/NBK541101/ | access-date=2020-07-06 | page=}}</ref><ref name="pmid9459649">{{cite journal |author=de Broe ME, Elseviers MM |title=Analgesic nephropathy |journal=N. Engl. J. Med. |volume=338 |issue=7 |pages=446–52 |year=1998 |month=February |pmid=9459649 |doi= |url=http://content.nejm.org/cgi/pmidlookup?view=short&pmid=9459649&promo=ONFLNS19}}</ref> | ||
* The pathology of classic analgesic nephropathy caused by phenacetin and phenacetin-containing analgesics was caused by capillary sclerosis in the renal medulla due to toxic metabolites of phenacetin which would lead to:<ref name="pmid6641031">{{cite journal| author=Mihatsch MJ, Hofer HO, Gudat F, Knüsli C, Torhorst J, Zollinger HU| title=Capillary sclerosis of the urinary tract and analgesic nephropathy. | journal=Clin Nephrol | year= 1983 | volume= 20 | issue= 6 | pages= 285-301 | pmid=6641031 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6641031 }} </ref><ref name="pmid16891638">{{cite journal| author=Mihatsch MJ, Khanlari B, Brunner FP| title=Obituary to analgesic nephropathy--an autopsy study. | journal=Nephrol Dial Transplant | year= 2006 | volume= 21 | issue= 11 | pages= 3139-45 | pmid=16891638 | doi=10.1093/ndt/gfl390 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16891638 }} </ref> | |||
** Papillary necrosis | |||
** Tubulointerstitial nephropathy | |||
** Cortical atrophy | |||
==References== | ==References== | ||
Revision as of 08:13, 6 July 2020
|
Analgesic nephropathy Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Analgesic nephropathy diagnostic study of choice On the Web |
|
American Roentgen Ray Society Images of Analgesic nephropathy diagnostic study of choice |
|
Analgesic nephropathy diagnostic study of choice in the news |
|
Risk calculators and risk factors for Analgesic nephropathy diagnostic study of choice |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]
Overview
Diagnostic Study of Choice
Renal Biopsy
- Renal biopsy is the diagnostic study of choice.[1]
- However, renal biopsy is an invasive procedure and there is risk of complications, therefore CT scan without contrast of the abdomen is usually preferred.[1][2]
- The pathology of classic analgesic nephropathy caused by phenacetin and phenacetin-containing analgesics was caused by capillary sclerosis in the renal medulla due to toxic metabolites of phenacetin which would lead to:[3][4]
- Papillary necrosis
- Tubulointerstitial nephropathy
- Cortical atrophy
References
- ↑ 1.0 1.1 Template:Cite
- ↑ de Broe ME, Elseviers MM (1998). "Analgesic nephropathy". N. Engl. J. Med. 338 (7): 446–52. PMID 9459649. Unknown parameter
|month=ignored (help) - ↑ Mihatsch MJ, Hofer HO, Gudat F, Knüsli C, Torhorst J, Zollinger HU (1983). "Capillary sclerosis of the urinary tract and analgesic nephropathy". Clin Nephrol. 20 (6): 285–301. PMID 6641031.
- ↑ Mihatsch MJ, Khanlari B, Brunner FP (2006). "Obituary to analgesic nephropathy--an autopsy study". Nephrol Dial Transplant. 21 (11): 3139–45. doi:10.1093/ndt/gfl390. PMID 16891638.