Analgesic nephropathy history and symptoms: Difference between revisions
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==History and Symptoms== | ==History and Symptoms== | ||
History, symptoms and and clinical findings in patients with analgesic nephropathy includes: | History, symptoms and and clinical findings in patients with analgesic nephropathy includes:<ref name="pmid7002190">{{cite journal| author=Nanra RS| title=Clinical and pathological aspects of analgesic nephropathy. | journal=Br J Clin Pharmacol | year= 1980 | volume= 10 Suppl 2 | issue= | pages= 359S-368S | pmid=7002190 | doi=10.1111/j.1365-2125.1980.tb01824.x | pmc=1430193 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7002190 }} </ref><ref name="pmid362034">{{cite journal| author=Nanra RS, Stuart-Taylor J, de Leon AH, White KH| title=Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia. | journal=Kidney Int | year= 1978 | volume= 13 | issue= 1 | pages= 79-92 | pmid=362034 | doi=10.1038/ki.1978.11 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=362034 }} </ref> | ||
* [[Headache]] | * [[Headache]] | ||
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* [[Anemia]] (60%) | * [[Anemia]] (60%) | ||
* [[Mental disorder|Psychiatric disorder]] | * [[Mental disorder|Psychiatric disorder]] | ||
* [[Urinary tract infection|Urinary tract infections]] (15-60%) | * [[Urinary tract infection|Urinary tract infections]] (15-60%) | ||
* Sterile [[pyuria]] (95%) | * Sterile [[pyuria]] (95%) | ||
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* [[Acidosis]] | * [[Acidosis]] | ||
* Passage of papillae | * Passage of papillae | ||
* [[Flanks|Flank]] or [[Abdomen|abdominal]] pain | * [[Flanks|Flank]] or [[Abdomen|abdominal]] pain | ||
==References== | ==References== | ||
Revision as of 12:29, 6 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
History and Symptoms
| Finding | Proportion affected |
|---|---|
| Headache | 35-100% |
| Pyuria | 50-100% |
| Anemia | 60-90% |
| Hypertension | 15-70% |
| Gastrointestinal symptoms | 40-60% |
| Urinary tract infection | 30-60% |
Common findings in patients with analgesic nephropathy include headache, anemia, high blood pressure (hypertension), and white blood cells in the urine (pyuria).[1] Some individuals with analgesic nephropathy may also have protein in their urine (proteinuria).[2]
Overview
Common findings in patients with analgesic nephropathy include: headache, upper gastrointestinal disease (such as peptic ulcer), anemia, urinary tract infections, pyuria and hypertension.
History and Symptoms
History, symptoms and and clinical findings in patients with analgesic nephropathy includes:[3][2]
- Headache
- Upper gastrointestinal disease (such as peptic ulcer)
- Anemia (60%)
- Psychiatric disorder
- Urinary tract infections (15-60%)
- Sterile pyuria (95%)
- Hypertension (15-70%)
- Tubular epithelial celluria
- Microscopic hematuria (35%)
- Significant proteinuria (greater than 0.3 gr daily (40%)
- Transitional cell tumours of the urothelium (in abuse of analgesics containing phenacetin)
- Renal papillary carcinoma
- Varying degrees of renal failure (over 85%)
- Clinical gout (5%)
- Acidosis
- Passage of papillae
- Flank or abdominal pain
References
- ↑ 1.0 1.1 Murray TG, Goldberg M (1978). "Analgesic-associated nephropathy in the U.S.A.: epidemiologic, clinical and pathogenetic features". Kidney Int. 13 (1): 64–71. PMID 713270. Unknown parameter
|month=ignored (help) - ↑ 2.0 2.1 Nanra RS, Stuart-Taylor J, de Leon AH, White KH (1978). "Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia". Kidney Int. 13 (1): 79–92. PMID 362034. Unknown parameter
|month=ignored (help) - ↑ Nanra RS (1980). "Clinical and pathological aspects of analgesic nephropathy". Br J Clin Pharmacol. 10 Suppl 2: 359S–368S. doi:10.1111/j.1365-2125.1980.tb01824.x. PMC 1430193. PMID 7002190.