Analgesic nephropathy physical examination: Difference between revisions
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{{Analgesic nephropathy}} | {{Analgesic nephropathy}} | ||
{{CMG}} {{AE}} {{SHA}} | |||
== Overview == | == Overview == | ||
Common findings in patients with analgesic nephropathy include: [[headache]], upper gastrointestinal disease (such as [[peptic ulcer]]), [[anemia]], [[Urinary tract infection|urinary tract infections]], [[pyuria]] and [[hypertension]]. | |||
== Physical Examination == | == Physical Examination == | ||
< | History, symptoms and and clinical findings in patients with analgesic nephropathy includes:<ref name="pmid7002190">{{cite journal| author=Nanra RS| title=Clinical and pathological aspects of analgesic nephropathy. | journal=Br J Clin Pharmacol | year= 1980 | volume= 10 Suppl 2 | issue= | pages= 359S-368S | pmid=7002190 | doi=10.1111/j.1365-2125.1980.tb01824.x | pmc=1430193 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7002190 }} </ref><ref name="pmid362034">{{cite journal| author=Nanra RS, Stuart-Taylor J, de Leon AH, White KH| title=Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia. | journal=Kidney Int | year= 1978 | volume= 13 | issue= 1 | pages= 79-92 | pmid=362034 | doi=10.1038/ki.1978.11 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=362034 }} </ref> | ||
* [[Headache]] | |||
* Upper gastrointestinal disease (such as [[peptic ulcer]]) | |||
* [[Anemia]] (60%) | |||
* [[Mental disorder|Psychiatric disorder]] | |||
* [[Urinary tract infection|Urinary tract infections]] (15-60%) | |||
* Sterile [[pyuria]] (95%) | |||
* [[Hypertension]] (15-70%) | |||
* Tubular epithelial celluria | |||
* Microscopic [[hematuria]] (35%) | |||
* Significant [[proteinuria]] (greater than 0.3 gr daily (40%) | |||
* [[Transitional cell carcinoma|Transitional cell tumours]] of the [[urothelium]] (in abuse of [[Analgesic|analgesics]] containing [[phenacetin]]) | |||
* Renal papillary carcinoma | |||
* Varying degrees of [[Renal insufficiency|renal failure]] (over 85%) | |||
* Clinical [[gout]] (5%) | |||
* [[Acidosis]] | |||
* Passage of papillae | |||
* [[Flanks|Flank]] or [[Abdomen|abdominal]] pain | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 12:33, 6 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]
Overview
Common findings in patients with analgesic nephropathy include: headache, upper gastrointestinal disease (such as peptic ulcer), anemia, urinary tract infections, pyuria and hypertension.
Physical Examination
History, symptoms and and clinical findings in patients with analgesic nephropathy includes:[1][2]
- Headache
- Upper gastrointestinal disease (such as peptic ulcer)
- Anemia (60%)
- Psychiatric disorder
- Urinary tract infections (15-60%)
- Sterile pyuria (95%)
- Hypertension (15-70%)
- Tubular epithelial celluria
- Microscopic hematuria (35%)
- Significant proteinuria (greater than 0.3 gr daily (40%)
- Transitional cell tumours of the urothelium (in abuse of analgesics containing phenacetin)
- Renal papillary carcinoma
- Varying degrees of renal failure (over 85%)
- Clinical gout (5%)
- Acidosis
- Passage of papillae
- Flank or abdominal pain
References
- ↑ Nanra RS (1980). "Clinical and pathological aspects of analgesic nephropathy". Br J Clin Pharmacol. 10 Suppl 2: 359S–368S. doi:10.1111/j.1365-2125.1980.tb01824.x. PMC 1430193. PMID 7002190.
- ↑ Nanra RS, Stuart-Taylor J, de Leon AH, White KH (1978). "Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia". Kidney Int. 13 (1): 79–92. doi:10.1038/ki.1978.11. PMID 362034.