Analgesic nephropathy history and symptoms: Difference between revisions
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{{Analgesic nephropathy}} | {{Analgesic nephropathy}} | ||
{{CMG}} {{AE}} {{SHA}} | {{CMG}} {{AE}} {{SHA}} | ||
==Overview== | ==<s>Overview</s>== | ||
==History and Symptoms== | ==<s>History and Symptoms</s>== | ||
{| class="wikitable" style="float:center; margin:10px" | {| class="wikitable" style="float:center; margin:10px" | ||
|+Clinical findings in analgesic nephropathy<ref name="pmid713270" /> | |+<s>Clinical findings in analgesic nephropathy<ref name="pmid713270" /></s> | ||
|- | |- | ||
! Finding | !<s>Finding</s> | ||
! Proportion affected | !<s>Proportion affected</s> | ||
|- | |- | ||
| Headache | |<s>Headache</s> | ||
| 35-100% | |<s>35-100%</s> | ||
|- | |- | ||
| Pyuria | |<s>Pyuria</s> | ||
| 50-100% | |<s>50-100%</s> | ||
|- | |- | ||
| Anemia | |<s>Anemia</s> | ||
| 60-90% | |<s>60-90%</s> | ||
|- | |- | ||
| Hypertension | |<s>Hypertension</s> | ||
| 15-70% | |<s>15-70%</s> | ||
|- | |- | ||
| Gastrointestinal symptoms | |<s>Gastrointestinal symptoms</s> | ||
| 40-60% | |<s>40-60%</s> | ||
|- | |- | ||
| Urinary tract infection | |<s>Urinary tract infection</s> | ||
| 30-60% | |<s>30-60%</s> | ||
|} | |} | ||
Common findings in patients with analgesic nephropathy include [[headache]], [[anemia]], high blood pressure ([[hypertension]]), and white blood cells in the urine ([[pyuria]]).<ref name="pmid713270">{{cite journal |author=Murray TG, Goldberg M |title=Analgesic-associated nephropathy in the U.S.A.: epidemiologic, clinical and pathogenetic features |journal=Kidney Int. |volume=13 |issue=1 |pages=64–71 |year=1978 |month=January |pmid=713270 |doi= |url=}}</ref> Some individuals with analgesic nephropathy may also have protein in their urine ([[proteinuria]]).<ref name="pmid362034">{{cite journal |author=Nanra RS, Stuart-Taylor J, de Leon AH, White KH |title=Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia |journal=Kidney Int. |volume=13 |issue=1 |pages=79–92 |year=1978 |month=January |pmid=362034 |doi= |url=}}</ref> | <s>Common findings in patients with analgesic nephropathy include [[headache]], [[anemia]], high blood pressure ([[hypertension]]), and white blood cells in the urine ([[pyuria]]).<ref name="pmid713270">{{cite journal |author=Murray TG, Goldberg M |title=Analgesic-associated nephropathy in the U.S.A.: epidemiologic, clinical and pathogenetic features |journal=Kidney Int. |volume=13 |issue=1 |pages=64–71 |year=1978 |month=January |pmid=713270 |doi= |url=}}</ref> Some individuals with analgesic nephropathy may also have protein in their urine ([[proteinuria]]).<ref name="pmid362034">{{cite journal |author=Nanra RS, Stuart-Taylor J, de Leon AH, White KH |title=Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia |journal=Kidney Int. |volume=13 |issue=1 |pages=79–92 |year=1978 |month=January |pmid=362034 |doi= |url=}}</ref></s> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]
Overview
History and Symptoms
Common findings in patients with analgesic nephropathy include headache, anemia, high blood pressure (hypertension), and white blood cells in the urine (pyuria).[1] Some individuals with analgesic nephropathy may also have protein in their urine (proteinuria).[2]
Overview
Common findings in patients with analgesic nephropathy include: headache, upper gastrointestinal disease (such as peptic ulcer), anemia, urinary tract infections, pyuria and hypertension.
History and Symptoms
History, symptoms and and clinical findings in patients with analgesic nephropathy includes:[3][2]
- Headache
- Upper gastrointestinal disease (such as peptic ulcer)
- Anemia (60%)
- Psychiatric disorder
- Urinary tract infections (15-60%)
- Sterile pyuria (95%)
- Hypertension (15-70%)
- Tubular epithelial celluria
- Microscopic hematuria (35%)
- Significant proteinuria (greater than 0.3 gr daily (40%)
- Transitional cell tumours of the urothelium (in abuse of analgesics containing phenacetin)
- Renal papillary carcinoma
- Varying degrees of renal failure (over 85%)
- Clinical gout (5%)
- Acidosis
- Passage of papillae
- Flank or abdominal pain
References
- ↑ 1.0 1.1 Murray TG, Goldberg M (1978). "Analgesic-associated nephropathy in the U.S.A.: epidemiologic, clinical and pathogenetic features". Kidney Int. 13 (1): 64–71. PMID 713270. Unknown parameter
|month=ignored (help) - ↑ 2.0 2.1 Nanra RS, Stuart-Taylor J, de Leon AH, White KH (1978). "Analgesic nephropathy: etiology, clinical syndrome, and clinicopathologic correlations in Australia". Kidney Int. 13 (1): 79–92. PMID 362034. Unknown parameter
|month=ignored (help) - ↑ Nanra RS (1980). "Clinical and pathological aspects of analgesic nephropathy". Br J Clin Pharmacol. 10 Suppl 2: 359S–368S. doi:10.1111/j.1365-2125.1980.tb01824.x. PMC 1430193. PMID 7002190.