Renal agenesis physical examination: Difference between revisions
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== Physical Examination == | == Physical Examination == | ||
Patients with unilateral renal agenesis (URA) have an increased risk for [[proteinuria]], [[hypertension]], and [[renal insufficiency]]. Therefore, patients, even those with normal solitary kidney, should be followed up with:<ref name="pmid1457321">{{cite journal| author=Argueso LR, Ritchey ML, Boyle ET, Milliner DS, Bergstralh EJ, Kramer SA| title=Prognosis of patients with unilateral renal agenesis. | journal=Pediatr Nephrol | year= 1992 | volume= 6 | issue= 5 | pages= 412-6 | pmid=1457321 | doi=10.1007/BF00873996 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1457321 }} </ref><ref name="pmid30734167">{{cite journal| author=Xu Q, Wu H, Zhou L, Xie J, Zhang W, Yu H | display-authors=etal| title=The clinical characteristics of Chinese patients with unilateral renal agenesis. | journal=Clin Exp Nephrol | year= 2019 | volume= 23 | issue= 6 | pages= 792-798 | pmid=30734167 | doi=10.1007/s10157-019-01704-x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30734167 }} </ref> | |||
*[[Blood pressure]] | *[[Blood pressure]] | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]
Overview
Follow up with checking of blood pressure (for hypertension) and urinalysis (for proteinuria and renal insufficiency) should be considered in patients with unilateral renal agenesis (URA). Checking for other contralateral congenital anomaly of kidney or urinary tract (CAKUT) such as VUR (vesicoureteral reflux) and PUJO (pelviureteric junction obstruction), extra-renal anomalies in different organs (such as cardiac, lung, gastrointestinal, genital, skeleton, and vertebral) , and associated syndromes and sequences (such as VACTERL, CHARGE and Trisomy 18) should be considered when URA is diagnosed.
Physical Examination
Patients with unilateral renal agenesis (URA) have an increased risk for proteinuria, hypertension, and renal insufficiency. Therefore, patients, even those with normal solitary kidney, should be followed up with:[1][2]
- Blood pressure
- Check for hypertension
- Urinalysis
URA may be isolated or associated with other anomalies and malformations. Therefore, screening and checking for other contralateral congenital anomaly of kidney or urinary tract (CAKUT), extra-renal anomalies, and associated syndromes and sequences (such as VACTERL, CHARGE and Trisomy 18) should be considered when URA is diagnosed. Some of the findings that may be important to consider in the physical exam of URA include:[3][4]
- Urinary tract
- Associated CAKUT
- VUR (vesicoureteral reflux)
- PUJO (pelviureteric junction obstruction)
- PUV (posterior urethral valves)
- Duplex kidney
- Ureterocele
- Megaureter
- Urinary tract infection
- Associated CAKUT
- Associated extra-renal anomalies
- Skull
- Dysraphism parieto-occipital
- Macrocephaly
- Anencephaly
- Spine
- Spina bifida
- Hemivertebra
- Coccygeal congenital fistula
- Caudal regression
- Skeleton
- Face
- Thorax
- Diaphragmatic hernia
- Thoracic haemangioma
- Heart
- Lung
- Congenital lung cyst
- Agenesis of lung
- Gastrointestinal tract
- Genital system
- Female tract anomalies
- Unicornate uterus
- Developmental ovarian cyst
- Hypospadias
- Epispadias
- Ambiguous genitalia
- Female tract anomalies
- Skull
References
- ↑ Argueso LR, Ritchey ML, Boyle ET, Milliner DS, Bergstralh EJ, Kramer SA (1992). "Prognosis of patients with unilateral renal agenesis". Pediatr Nephrol. 6 (5): 412–6. doi:10.1007/BF00873996. PMID 1457321.
- ↑ Xu Q, Wu H, Zhou L, Xie J, Zhang W, Yu H; et al. (2019). "The clinical characteristics of Chinese patients with unilateral renal agenesis". Clin Exp Nephrol. 23 (6): 792–798. doi:10.1007/s10157-019-01704-x. PMID 30734167.
- ↑ Laurichesse Delmas H, Kohler M, Doray B, Lémery D, Francannet C, Quistrebert J; et al. (2017). "Congenital unilateral renal agenesis: Prevalence, prenatal diagnosis, associated anomalies. Data from two birth-defect registries". Birth Defects Res. 109 (15): 1204–1211. doi:10.1002/bdr2.1065. PMID 28722320.
- ↑ Westland R, Schreuder MF, Ket JC, van Wijk JA (2013). "Unilateral renal agenesis: a systematic review on associated anomalies and renal injury". Nephrol Dial Transplant. 28 (7): 1844–55. doi:10.1093/ndt/gft012. PMID 23449343.