Chest pain laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Aisha Adigun, B.Sc., M.D.[2]

Overview

Serial troponins and CK-MB should be ordered. Additional laboratory tests include serum electrolytes, a complete blood count, renal function tests, and liver function tests.

Laboratory Findings

On the basis of the above, a number of tests may be ordered:

Cardiac Markers

• Troponin I or T are now cardiac marker of choice and are preferred over creatine kinase.
• No one marker gives accurate diagnosis so commonly two markers are used for instance Troponin I or T with creatine kinase (and CK-MB fraction in many hospitals)

Blood Tests

• D-dimer (when suspicion for pulmonary embolism, aortic dissection)
• Complete blood count may be elevated in infectious causes of chest pain such as pericarditis, pneumonia, mediastinitis.
• BNP and NT-proBNP may help recognize or eliminate heart failure as a cause of chest pain in a presenting patient.
• Arterial blood gas may be done if pulmonary embolism is a differential diagnosis in a patient presenting with chest pain.
• Electrolytes
• Renal function (creatinine)
• Liver function tests

Overview

An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].

OR

Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].

OR

[Test] is usually normal for patients with [disease name].

OR

Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].

OR

There are no diagnostic laboratory findings associated with [disease name].

Laboratory Findings

There are no diagnostic laboratory findings associated with [disease name].

OR

An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].

OR

[Test] is usually normal among patients with [disease name].

OR

Laboratory findings consistent with the diagnosis of [disease name] include:

• [Abnormal test 1]
• [Abnormal test 2]
• [Abnormal test 3]

OR

Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].